|
| Protein |
|
| Gene Symbol | CIPC to neXtProt (NX_Q9C0C6) |
| Description | CLOCK-interacting pacemaker |
| Chromosome | 14 |
| Location | 14q24.3 (77564440 ~ 77583630) to Ensembl |
|
|
Sequene Features : Isoforms 1, Variants 9, PTMs 1 to neXtProt Sequence Features
|
|
Gene
Ontologies |
| GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
.rhythmic process
.negative regulation of transcription, DNA-templated
.negative regulation of circadian rhythm
.transcription, DNA-templated |
.N/A |
.nucleus |
|
|
| |
|
| Proteomic Evidences |
|
| |
|
| Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
|
| 2015-01-01 | | protein level | | | | | | | 1 |
| 9 |
| 1 |
|
| 2014-09-19 | | protein level | | | | | | | 1 |
| 28 |
| 1 |
|
| 2014-05-27 | | protein level | | | | | | | 1 |
| 28 |
| 1 |
|
| 2014-02-25 | | protein level | | | | | | | 1 |
| 28 |
| 1 |
|
| 2013-12-09 | | protein level | | | | | | | 1 |
| 23 |
| 1 |
|
| 2013-11-01 | | protein level | | | | | | | 1 |
| 19 |
| 1 |
|
| 2013-09-12 | | protein level | | | | | | | 1 |
| 19 |
| 1 |
|
| 2013-08-17 | | protein level | | | | | | | 1 |
| 19 |
| 1 |
|
| 2013-07-15 | | protein level | | | | | | | 1 |
| 13 |
| 1 |
|
| 2013-06-11 | | protein level | | | | | | | 1 |
| 13 |
| 1 |
|
| 2013-02-12 | | transcript level | | | | | | | 1 |
| 6 |
| 0 |
|
| 2012-12-20 | | transcript level | | | | | | | 1 |
| 6 |
| 0 |
|
| 2012-10-30 | | transcript level | | | | | | | 1 |
| 6 |
| 0 |
|
| 2012-10-07 | | transcript level | | | | | | | 1 |
| 6 |
| 0 |
|
| 2012-08-24 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
|
| 2012-07-28 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
|
| 2012-06-08 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
|
| 2012-05-07 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
|
| 2012-04-10 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
|
| 2012-01-13 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
| 2011-12-20 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
| 2011-11-11 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
| 2011-08-23 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
|
|
| |
|
| Protein Isoforms |
|
| |
| |
|
| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
|
|
| |
|
| Interacting Partners |
|
| |
|
| No. |
Exp. ref. |
Symbol |
|
PE |
Pr |
Ab |
Di |
|
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
| 1 |
EBI-5654244,EBI-913954 |
RABGEF1 |
|
| | | | |
.negative regulation of Kit signaling pathway
.negative regulation of interleukin-6 secretion
.regulation of Fc receptor mediated stimulatory signaling pathway
+ 9 more... |
.Rab GTPase binding
.Rab guanyl-nucleotide exchange factor activity
.zinc ion binding
+ 2 more... |
.recycling endosome
.vesicle
.early endosome |
|
|
| |
|
| EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
|
| |
|
| Body Sites | |
| Tissues | TPM* | |
|
| bladder | 33 | |
| blood | 8 | |
| bone | 27 | |
| bone marrow | 41 | |
| brain | 154 | |
| cervix | 20 | |
| connective tissue | 13 | |
| embryonic tissue | 23 | |
| esophagus | 99 | |
| eye | 23 | |
| heart | 22 | |
| intestine | 12 | |
| kidney | 9 | |
| larynx | 85 | |
| liver | 14 | |
| lung | 23 | |
| lymph | 22 | |
| mammary gland | 33 | |
| mouth | 75 | |
| muscle | 28 | |
| ovary | 9 | |
| pancreas | 23 | |
| parathyroid | 48 | |
| pharynx | 24 | |
| pituitary gland | 242 | |
| placenta | 7 | |
| prostate | 15 | |
| skin | 14 | |
| stomach | 83 | |
| testis | 25 | |
| thymus | 25 | |
| thyroid | 21 | |
| trachea | 135 | |
| uterus | 64 | |
| vascular | 19 | |
|
| Health State | |
| Tissues | TPM* | |
|
| normal | 57 | |
| breast (mammary gland) tumor | 32 | |
| cervical tumor | 28 | |
| chondrosarcoma | 24 | |
| colorectal tumor | 8 | |
| esophageal tumor | 115 | |
| gastrointestinal tumor | 67 | |
| germ cell tumor | 11 | |
| glioma | 9 | |
| head and neck tumor | 59 | |
| leukemia | 10 | |
| liver tumor | 20 | |
| lung tumor | 9 | |
| lymphoma | 13 | |
| non-neoplasia | 93 | |
| primitive neuroectodermal tumor of the CNS | 23 | |
| prostate cancer | 9 | |
| skin tumor | 7 | |
| soft tissue/muscle tissue tumor | 39 | |
| uterine tumor | 44 | |
|
| Developmental Stage | |
| Tissues | TPM* | |
|
| adult | 31 | |
| embryoid body | 14 | |
| blastocyst | 48 | |
| fetus | 48 | |
| infant | 42 | |
| juvenile | 17 | |
|
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
| |
|
| Expression level of Protein (ref. Human Protein Atlas) |
|
| |
|
| RNA-Seq. | |
| Tissues | FPKM | |
|
| adipose tissue | 10.9 | |
| adrenal gland | 9.6 | |
| appendix | 8.8 | |
| bone marrow | 2.3 | |
| cerebral cortex | 30.4 | |
| colon | 16.7 | |
| duodenum | 9.2 | |
| esophagus | 20.9 | |
| gallbladder | 9.3 | |
| heart muscle | 29.5 | |
| kidney | 11.5 | |
| liver | 7.4 | |
| lung | 10.6 | |
| lymph node | 7.6 | |
| ovary | 8 | |
| pancreas | 4.2 | |
| placenta | 8 | |
| prostate | 22.8 | |
| salivary gland | 14 | |
| skin | 9.1 | |
| small intestine | 9.7 | |
| spleen | 7.8 | |
| stomach | 8.9 | |
| testis | 12.1 | |
| thyroid gland | 19.9 | |
| urinary bladder | 14.6 | |
|
| Cancer | |
| Tumor | Number of patients and Staining levels | |
| breast cancer | |
| carcinoid | |
| cervical cancer | |
| colorectal cancer | |
| endometrial cancer | |
| glioma | |
| head and neck cancer | |
| liver cancer | |
| lung cancer | |
| lymphoma | |
| melanoma | |
| ovarian cancer | |
| pancreatic cancer | |
| prostate cancer | |
| renal cancer | |
| skin cancer | |
| stomach cancer | |
| testis cancer | |
| thyroid cancer | |
| urothelial cancer | |
|
| RNA-seq colour codes |
|
|
Highly expressed RNAs (FPKM >50) | |
|
Moderately expressed RNAs (50> FPKM >10) | |
|
Lower expressed RNAs (10> FPKM >1) | |
|
The lowest expressed RNAs (FPKM value of 0 or 1) |
|
| Staining level colour codes |
|
|
Highly expressed protein | |
|
Moderately expressed protein | |
|
Lower expressed protein | |
|
Not Detected |
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| |
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> Protein (NX_Q9C0C6)