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> Protein (NX_Q9C0C6)
Protein (NX_Q9C0C6)
Protein
Gene SymbolCIPC to neXtProt (NX_Q9C0C6)
DescriptionCLOCK-interacting pacemaker
Chromosome14
Location14q24.3 (77564440 ~ 77583630) to Ensembl
Sequene Features : Isoforms 1, Variants 9, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.rhythmic process
.negative regulation of transcription, DNA-templated
.negative regulation of circadian rhythm
.transcription, DNA-templated
.N/A .nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 9 1
2014-09-19protein level
1 28 1
2014-05-27protein level
1 28 1
2014-02-25protein level
1 28 1
2013-12-09protein level
1 23 1
2013-11-01protein level
1 19 1
2013-09-12protein level
1 19 1
2013-08-17protein level
1 19 1
2013-07-15protein level
1 13 1
2013-06-11protein level
1 13 1
2013-02-12transcript level
1 6 0
2012-12-20transcript level
1 6 0
2012-10-30transcript level
1 6 0
2012-10-07transcript level
1 6 0
2012-08-24transcript level
1 4 0
2012-07-28transcript level
1 4 0
2012-06-08transcript level
1 4 0
2012-05-07transcript level
1 4 0
2012-04-10transcript level
1 4 0
2012-01-13transcript level
1 5 0
2011-12-20transcript level
1 5 0
2011-11-11transcript level
1 5 0
2011-08-23transcript level
1 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9C0C6-1
16 0 0 42665.5913
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5654244,EBI-913954 RABGEF1  
  .negative regulation of Kit signaling pathway
.negative regulation of interleukin-6 secretion
.regulation of Fc receptor mediated stimulatory signaling pathway
  + 9 more...
.Rab GTPase binding
.Rab guanyl-nucleotide exchange factor activity
.zinc ion binding
  + 2 more...
.recycling endosome
.vesicle
.early endosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood8
bone27
bone marrow41
brain154
cervix20
connective tissue13
embryonic tissue23
esophagus99
eye23
heart22
intestine12
kidney9
larynx85
liver14
lung23
lymph22
mammary gland33
mouth75
muscle28
ovary9
pancreas23
parathyroid48
pharynx24
pituitary gland242
placenta7
prostate15
skin14
stomach83
testis25
thymus25
thyroid21
trachea135
uterus64
vascular19
Health State
TissuesTPM*
normal57
breast (mammary gland) tumor32
cervical tumor28
chondrosarcoma24
colorectal tumor8
esophageal tumor115
gastrointestinal tumor67
germ cell tumor11
glioma9
head and neck tumor59
leukemia10
liver tumor20
lung tumor9
lymphoma13
non-neoplasia93
primitive neuroectodermal tumor of the CNS23
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor39
uterine tumor44
Developmental Stage
TissuesTPM*
adult31
embryoid body14
blastocyst48
fetus48
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.9
adrenal gland9.6
appendix8.8
bone marrow2.3
cerebral cortex30.4
colon16.7
duodenum9.2
esophagus20.9
gallbladder9.3
heart muscle29.5
kidney11.5
liver7.4
lung10.6
lymph node7.6
ovary8
pancreas4.2
placenta8
prostate22.8
salivary gland14
skin9.1
small intestine9.7
spleen7.8
stomach8.9
testis12.1
thyroid gland19.9
urinary bladder14.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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