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Protein |
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Gene Symbol | CIPC to neXtProt (NX_Q9C0C6) |
Description | CLOCK-interacting pacemaker |
Chromosome | 14 |
Location | 14q24.3 (77564440 ~ 77583630) to Ensembl |
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Sequene Features : Isoforms 1, Variants 9, PTMs 1 to neXtProt Sequence Features
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Gene Ontologies |
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
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.rhythmic process .negative regulation of transcription, DNA-templated .negative regulation of circadian rhythm .transcription, DNA-templated |
.N/A |
.nucleus |
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Proteomic Evidences |
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Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
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2015-01-01 | | protein level | | | | | | | 1 |
| 9 |
| 1 |
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2014-09-19 | | protein level | | | | | | | 1 |
| 28 |
| 1 |
|
2014-05-27 | | protein level | | | | | | | 1 |
| 28 |
| 1 |
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2014-02-25 | | protein level | | | | | | | 1 |
| 28 |
| 1 |
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2013-12-09 | | protein level | | | | | | | 1 |
| 23 |
| 1 |
|
2013-11-01 | | protein level | | | | | | | 1 |
| 19 |
| 1 |
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2013-09-12 | | protein level | | | | | | | 1 |
| 19 |
| 1 |
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2013-08-17 | | protein level | | | | | | | 1 |
| 19 |
| 1 |
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2013-07-15 | | protein level | | | | | | | 1 |
| 13 |
| 1 |
|
2013-06-11 | | protein level | | | | | | | 1 |
| 13 |
| 1 |
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2013-02-12 | | transcript level | | | | | | | 1 |
| 6 |
| 0 |
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2012-12-20 | | transcript level | | | | | | | 1 |
| 6 |
| 0 |
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2012-10-30 | | transcript level | | | | | | | 1 |
| 6 |
| 0 |
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2012-10-07 | | transcript level | | | | | | | 1 |
| 6 |
| 0 |
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2012-08-24 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
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2012-07-28 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
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2012-06-08 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
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2012-05-07 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
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2012-04-10 | | transcript level | | | | | | | 1 |
| 4 |
| 0 |
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2012-01-13 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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2011-12-20 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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2011-11-11 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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2011-08-23 | | transcript level | | | | | | | 1 |
| 5 |
| 0 |
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Protein Isoforms |
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| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
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Interacting Partners |
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No. |
Exp. ref. |
Symbol |
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PE |
Pr |
Ab |
Di |
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GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
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1 |
EBI-5654244,EBI-913954 |
RABGEF1 |
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| | | | |
.negative regulation of Kit signaling pathway .negative regulation of interleukin-6 secretion .regulation of Fc receptor mediated stimulatory signaling pathway + 9 more... |
.Rab GTPase binding .Rab guanyl-nucleotide exchange factor activity .zinc ion binding + 2 more... |
.recycling endosome .vesicle .early endosome |
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EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
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Body Sites | |
Tissues | TPM* | |
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bladder | 33 | |
blood | 8 | |
bone | 27 | |
bone marrow | 41 | |
brain | 154 | |
cervix | 20 | |
connective tissue | 13 | |
embryonic tissue | 23 | |
esophagus | 99 | |
eye | 23 | |
heart | 22 | |
intestine | 12 | |
kidney | 9 | |
larynx | 85 | |
liver | 14 | |
lung | 23 | |
lymph | 22 | |
mammary gland | 33 | |
mouth | 75 | |
muscle | 28 | |
ovary | 9 | |
pancreas | 23 | |
parathyroid | 48 | |
pharynx | 24 | |
pituitary gland | 242 | |
placenta | 7 | |
prostate | 15 | |
skin | 14 | |
stomach | 83 | |
testis | 25 | |
thymus | 25 | |
thyroid | 21 | |
trachea | 135 | |
uterus | 64 | |
vascular | 19 | |
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Health State | |
Tissues | TPM* | |
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normal | 57 | |
breast (mammary gland) tumor | 32 | |
cervical tumor | 28 | |
chondrosarcoma | 24 | |
colorectal tumor | 8 | |
esophageal tumor | 115 | |
gastrointestinal tumor | 67 | |
germ cell tumor | 11 | |
glioma | 9 | |
head and neck tumor | 59 | |
leukemia | 10 | |
liver tumor | 20 | |
lung tumor | 9 | |
lymphoma | 13 | |
non-neoplasia | 93 | |
primitive neuroectodermal tumor of the CNS | 23 | |
prostate cancer | 9 | |
skin tumor | 7 | |
soft tissue/muscle tissue tumor | 39 | |
uterine tumor | 44 | |
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Developmental Stage | |
Tissues | TPM* | |
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adult | 31 | |
embryoid body | 14 | |
blastocyst | 48 | |
fetus | 48 | |
infant | 42 | |
juvenile | 17 | |
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TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
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Expression level of Protein (ref. Human Protein Atlas) |
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RNA-Seq. | |
Tissues | FPKM | |
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adipose tissue | 10.9 | |
adrenal gland | 9.6 | |
appendix | 8.8 | |
bone marrow | 2.3 | |
cerebral cortex | 30.4 | |
colon | 16.7 | |
duodenum | 9.2 | |
esophagus | 20.9 | |
gallbladder | 9.3 | |
heart muscle | 29.5 | |
kidney | 11.5 | |
liver | 7.4 | |
lung | 10.6 | |
lymph node | 7.6 | |
ovary | 8 | |
pancreas | 4.2 | |
placenta | 8 | |
prostate | 22.8 | |
salivary gland | 14 | |
skin | 9.1 | |
small intestine | 9.7 | |
spleen | 7.8 | |
stomach | 8.9 | |
testis | 12.1 | |
thyroid gland | 19.9 | |
urinary bladder | 14.6 | |
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Cancer | |
Tumor | Number of patients and Staining levels | |
breast cancer | |
carcinoid | |
cervical cancer | |
colorectal cancer | |
endometrial cancer | |
glioma | |
head and neck cancer | |
liver cancer | |
lung cancer | |
lymphoma | |
melanoma | |
ovarian cancer | |
pancreatic cancer | |
prostate cancer | |
renal cancer | |
skin cancer | |
stomach cancer | |
testis cancer | |
thyroid cancer | |
urothelial cancer | |
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RNA-seq colour codes |
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Highly expressed RNAs (FPKM >50) |
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Moderately expressed RNAs (50> FPKM >10) |
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Lower expressed RNAs (10> FPKM >1) |
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The lowest expressed RNAs (FPKM value of 0 or 1) |
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Staining level colour codes |
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Highly expressed protein |
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Moderately expressed protein |
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Lower expressed protein |
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Not Detected |
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