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> Protein (NX_Q9C0F1)
Protein (NX_Q9C0F1)
Protein
Gene SymbolCEP44 to neXtProt (NX_Q9C0F1)
DescriptionCentrosomal protein of 44 kDa
Chromosome4
Location4q34.1 (175204828 ~ 175254531) to Ensembl
Sequene Features : Isoforms 2, Variants 47, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .midbody
.centrosome
.cytoplasm
.spindle pole
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 47 2
2014-09-19protein level
2 39 2
2014-05-27protein level
2 39 2
2014-02-25protein level
2 38 2
2013-12-09protein level
2 29 2
2013-11-01protein level
2 28 2
2013-09-12protein level
2 28 2
2013-08-17protein level
2 28 2
2013-07-15protein level
2 21 2
2013-06-11protein level
2 21 2
2013-02-12protein level
2 13 2
2012-12-20protein level
2 12 2
2012-10-30protein level
2 15 2
2012-10-07protein level
2 15 1
2012-08-24protein level
2 15 1
2012-07-28protein level
2 15 1
2012-06-08protein level
2 15 1
2012-05-07protein level
2 13 1
2012-04-10protein level
2 13 1
2012-01-13protein level
2 8 1
2011-12-20protein level
2 8 1
2011-11-11protein level
2 8 1
2011-08-23protein level
2 8 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9C0F1-1
2 13 0 44111.2678
NX_Q9C0F1-2
2 13 0 44733.4733
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744115,EBI-357622 PSMD3  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 22 more...
.enzyme regulator activity .extracellular exosome
.proteasome accessory complex
.membrane
  + 6 more...
2 EBI-744115,EBI-6447217 HYPM  
  .N/A .N/A .N/A
3 EBI-744115,EBI-6393536 ERAL1  
  .ribosomal small subunit assembly .poly(A) RNA binding
.ribosomal small subunit binding
.rRNA binding
.GTP binding
.intermediate filament cytoskeleton
.actin cytoskeleton
.mitochondrial matrix
  + 3 more...
4 EBI-744115,EBI-8639312 LMO1  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.zinc ion binding .nucleus
5 EBI-744115,EBI-745213 AQP1  
  .cation transmembrane transport
.maintenance of symbiont-containing vacuole by host
.ammonium transmembrane transport
  + 60 more...
.carbon dioxide transmembrane transporter activity
.nitric oxide transmembrane transporter activity
.transmembrane transporter activity
  + 8 more...
.extracellular exosome
.apical part of cell
.axon terminus
  + 12 more...
6 EBI-744115,EBI-359793 TXLNA  
  .activation of mitophagy in response to mitochondrial depolarization
.B cell activation
.cell proliferation
.exocytosis
.high molecular weight B cell growth factor receptor binding
.cytokine activity
.membrane
.cytoplasm
.extracellular region
7 EBI-744115,EBI-747693 NAA10  
  .N-terminal peptidyl-glutamic acid acetylation
.N-terminal peptidyl-serine acetylation
.internal protein amino acid acetylation
  + 2 more...
.peptide-glutamate-N-acetyltransferase activity
.peptide-serine-N-acetyltransferase activity
.N-acetyltransferase activity
.NatA complex
.cytosolic ribosome
.membrane
  + 4 more...
8 EBI-744115,EBI-713568 MAPK9  
  .positive regulation of apoptotic signaling pathway
.cellular response to growth factor stimulus
.cellular response to tumor necrosis factor
  + 45 more...
.cysteine-type endopeptidase activator activity involved in apoptotic process
.transcription factor binding
.ATP binding
.JUN kinase activity
.cytosol
.mitochondrion
.nucleoplasm
9 EBI-744115,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
10 EBI-744115,EBI-358049 BYSL  
  .cell proliferation
.female pregnancy
.cell adhesion
  + 2 more...
.poly(A) RNA binding .apical part of cell
.intracellular membrane-bounded organelle
.membrane
  + 3 more...
11 EBI-744115,EBI-2564275 DIP2A  
  .regulation of apoptotic process
.negative regulation of gene expression
.multicellular organismal development
.catalytic activity .cell surface
.nucleus
12 EBI-744115,EBI-710310 TCEA2  
  .positive regulation of transcription from RNA polymerase II promoter
.regulation of DNA-templated transcription, elongation
.DNA-templated transcription, elongation
.zinc ion binding
.DNA binding
.transcription elongation factor complex
.centrosome
.nucleoplasm
13 EBI-744115,EBI-10240044 LRRFIP1  
  .negative regulation of transcription, DNA-templated
.innate immune response
.positive regulation of type I interferon production
  + 2 more...
.protein homodimerization activity
.double-stranded RNA binding
.DNA binding
.plasma membrane
.cytoskeleton
.cytosol
  + 2 more...
14 EBI-744115,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
15 EBI-744115,EBI-10247271 FAM74A6  
  .N/A .N/A .N/A
16 EBI-744115,EBI-1051531 DHX57  
  .RNA processing .metal ion binding
.poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
.mitochondrion
.nucleus
17 EBI-744115,EBI-10247802 CCDC146  
  .N/A .N/A .centriole
18 EBI-744115,EBI-10181988 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
19 EBI-744115,EBI-10181188 BEND7  
  .N/A .N/A .extracellular exosome
20 EBI-744115,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
21 EBI-744115,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
22 EBI-744115,EBI-725997 TRIM41  
  .protein ubiquitination .ligase activity
.zinc ion binding
.cytoplasm
.nucleolus
23 EBI-744115,EBI-488533 ING5  
  .positive regulation of apoptotic signaling pathway
.negative regulation of growth
.positive regulation of transcription, DNA-templated
  + 7 more...
.methylated histone binding
.zinc ion binding
.chromatin binding
.MOZ/MORF histone acetyltransferase complex
.nucleoplasm
.nucleus
24 EBI-744115,EBI-366525 POP5  
  .tRNA processing .ribonuclease P activity .nucleolar ribonuclease P complex
25 EBI-744115,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
26 EBI-744115,EBI-748896 MRFAP1L1  
  .N/A .identical protein binding .N/A
27 EBI-744115,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
28 EBI-744115,EBI-2514922 RBM15  
  .placenta blood vessel development
.ventricular septum morphogenesis
.spleen development
  + 4 more...
.poly(A) RNA binding
.nucleotide binding
.nuclear membrane
.nucleoplasm
29 EBI-744115,EBI-748391 SCNM1  
  .RNA splicing
.mRNA processing
.metal ion binding
.enzyme binding
.nuclear speck
.nucleolus
.nucleus
30 EBI-744115,EBI-744794 TSGA10  
  .cell projection assembly
.spermatogenesis
.N/A .neuron projection
.nuclear membrane
.motile cilium
.cytoplasm
31 EBI-744115,EBI-742388 PLEKHF2  
  .protein transport .metal ion binding .early endosome membrane
.transport vesicle
.endoplasmic reticulum
32 EBI-744115,EBI-742038 ABI3  
  .regulation of cell migration
.movement of cell or subcellular component
.N/A .lamellipodium
.membrane
.cytoplasm
.intracellular
33 EBI-744115,EBI-396137 CDC23  
  .protein K11-linked ubiquitination
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
.positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
  + 11 more...
.ubiquitin-protein transferase activity .cytosol
.anaphase-promoting complex
.nucleoplasm
.intracellular
34 EBI-744115,EBI-741528 CHIC2  
  .Golgi to plasma membrane transport .N/A .plasma membrane
.Golgi-associated vesicle
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
brain13
embryonic tissue23
eye4
heart22
intestine4
kidney37
liver24
lung41
lymph node33
mammary gland52
mouth15
muscle37
pancreas9
parathyroid48
placenta17
prostate26
stomach62
testis36
thymus25
thyroid42
trachea19
uterus38
vascular19
Health State
TissuesTPM*
normal21
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor8
gastrointestinal tumor50
germ cell tumor7
head and neck tumor14
kidney tumor14
liver tumor10
lung tumor9
non-neoplasia10
primitive neuroectodermal tumor of the CNS23
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult24
embryoid body42
blastocyst32
fetus19
infant85
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.9
adrenal gland10.3
appendix9.5
bone marrow5.5
cerebral cortex7
colon7.4
duodenum9.6
esophagus8.5
gallbladder8.7
heart muscle7.6
kidney6.4
liver4
lung8.5
lymph node11.8
ovary13.1
pancreas2.8
placenta11.6
prostate9.7
salivary gland8.3
skin13
small intestine9
spleen9
stomach9.1
testis15.1
thyroid gland11.3
urinary bladder9.9
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleLow
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverLow
lungLow
lymph nodeLow
nasopharynxHigh
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2High
testisMedium
thyroid glandHigh
tonsilLow
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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