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> Protein (NX_Q9GZM8)
Protein (NX_Q9GZM8)
Protein
Gene SymbolNDEL1 to neXtProt (NX_Q9GZM8)
DescriptionNuclear distribution protein nudE-like 1
Chromosome17
Location17p13.1 (8316449 ~ 8393729) to Ensembl
Sequene Features : Isoforms 3, Variants 46, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.neuron projection extension
.neurofilament cytoskeleton organization
.centrosome localization
  + 20 more...
.oligopeptidase activity
.microtubule binding
.neurofilament cytoskeleton
.axon hillock
.cell leading edge
  + 10 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 46 8
2014-09-19protein level
3 38 8
2014-05-27protein level
3 38 8
2014-02-25protein level
3 38 8
2013-12-09protein level
3 30 8
2013-11-01protein level
3 29 8
2013-09-12protein level
3 29 8
2013-08-17protein level
3 29 8
2013-07-15protein level
2 20 8
2013-06-11protein level
2 20 8
2013-02-12protein level
2 14 18
2012-12-20protein level
2 14 18
2012-10-30protein level
2 18 18
2012-10-07protein level
2 18 9
2012-08-24protein level
2 16 9
2012-07-28protein level
2 16 9
2012-06-08protein level
2 31 9
2012-05-07protein level
2 27 9
2012-04-10protein level
2 27 9
2012-01-13protein level
2 21 9
2011-12-20protein level
2 21 9
2011-11-11protein level
2 21 8
2011-08-23protein level
2 21 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9GZM8-1
1 14 3 38351.3557
NX_Q9GZM8-2
4 14 3 40591.4453
NX_Q9GZM8-3
1 14 3 37016.7017
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-928842,EBI-715849 NDC80  
  .attachment of mitotic spindle microtubules to kinetochore
.cell division
.attachment of spindle microtubules to kinetochore
  + 7 more...
.identical protein binding
.structural constituent of cytoskeleton
.Ndc80 complex
.membrane
.cytosol
  + 5 more...
2 EBI-928842,EBI-740402 DTNB  
  .N/A .zinc ion binding .synapse
.cytoplasm
3 EBI-928842,EBI-743272 USP2  
  .regulation of proteasomal protein catabolic process
.protein stabilization
.positive regulation of skeletal muscle tissue development
  + 11 more...
.metal ion binding
.ubiquitin protein ligase binding
.cyclin binding
  + 2 more...
.perinuclear region of cytoplasm
.cell cortex
.centrosome
  + 2 more...
4 EBI-928842,EBI-749483 SNAPC5  
  .gene expression
.transcription initiation from RNA polymerase III promoter
.transcription from RNA polymerase III promoter
.transcription from RNA polymerase II promoter
.sequence-specific DNA binding transcription factor activity .nucleolus
.nucleoplasm
.nucleus
5 EBI-928842,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
6 EBI-928842,EBI-295222 XPA  
  .multicellular organism growth
.nucleotide-excision repair, DNA incision
.response to toxic substance
  + 6 more...
.metal ion binding
.protein homodimerization activity
.protein domain specific binding
.damaged DNA binding
.intercellular bridge
.Golgi apparatus
.cytoplasm
  + 2 more...
7 EBI-928842,EBI-2341576 BMI1  
  .positive regulation of ubiquitin-protein transferase activity
.positive regulation of fibroblast proliferation
.cellular protein metabolic process
  + 8 more...
.RING-like zinc finger domain binding
.zinc ion binding
.PRC1 complex
.PcG protein complex
.cytoplasm
  + 3 more...
8 EBI-928842,EBI-968343 CENPF  
  .DNA biosynthetic process
.regulation of cell cycle
.kinetochore assembly
  + 16 more...
.dynein binding
.protein homodimerization activity
.transcription factor binding
  + 2 more...
.perinuclear region of cytoplasm
.pronucleus
.midbody
  + 11 more...
9 EBI-928842,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
10 EBI-928842,EBI-10225757 ZNF844  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
11 EBI-928842,EBI-745226 AIMP2  
  .Type II pneumocyte differentiation
.positive regulation of protein ubiquitination
.gene expression
  + 3 more...
.N/A .membrane
.cytosol
.nucleus
12 EBI-928842,EBI-10241410 ZNF260  
  .multicellular organismal development
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytoplasm
.nucleoplasm
13 EBI-928842,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
14 EBI-928842,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
15 EBI-928842,EBI-2841978 ZNF544  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
16 EBI-928842,EBI-10257016 ZNF572  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
17 EBI-928842,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
18 EBI-928842,EBI-10175300 CCHCR1  
  .cell differentiation
.multicellular organismal development
.protein export from nucleus
.N/A .centriole
.cytoplasm
.nucleus
19 EBI-928842,EBI-8653994 ZNF599  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
20 EBI-928842,EBI-702235 PKP2  
  .regulation of tight junction assembly
.regulation of ventricular cardiac muscle cell action potential
.establishment of protein localization to plasma membrane
  + 19 more...
.cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
.alpha-catenin binding
.ion channel binding
  + 4 more...
.desmosome
.cell junction
.integral component of membrane
  + 7 more...
21 EBI-928842,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
22 EBI-928842,EBI-529989 DISC1  
  .positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.regulation of synapse maturation
.canonical Wnt signaling pathway
  + 10 more...
.N/A .postsynaptic membrane
.ciliary basal body
.cell junction
  + 4 more...
23 EBI-928842,EBI-10182361 MBIP  
  .histone H3 acetylation
.chromatin organization
.inactivation of MAPK activity involved in osmosensory signaling pathway
.identical protein binding
.protein kinase inhibitor activity
.cytoplasm
.nucleolus
.Ada2/Gcn5/Ada3 transcription activator complex
.nucleus
24 EBI-928842,EBI-10322527 ZNF180  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
25 EBI-928842,EBI-1105370 ZNF490  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
26 EBI-928842,EBI-765817 TRAF3IP3  
  .N/A .N/A .integral component of membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland242
ascites100
bladder66
blood171
bone111
bone marrow20
brain125
cervix20
connective tissue80
embryonic tissue4
eye57
heart111
intestine38
kidney104
larynx42
liver24
lung65
lymph node22
mammary gland33
mouth15
muscle9
nerve64
ovary59
pancreas18
placenta98
prostate47
salivary gland49
skin85
spleen131
stomach104
testis4
thymus37
thyroid85
trachea77
uterus68
vascular116
Health State
TissuesTPM*
normal95
breast (mammary gland) tumor42
cervical tumor28
chondrosarcoma72
colorectal tumor8
gastrointestinal tumor109
germ cell tumor3
glioma46
head and neck tumor7
kidney tumor145
leukemia10
liver tumor31
non-neoplasia124
ovarian tumor26
pancreatic tumor38
primitive neuroectodermal tumor of the CNS31
prostate cancer9
retinoblastoma43
skin tumor31
soft tissue/muscle tissue tumor39
uterine tumor11
Developmental Stage
TissuesTPM*
adult54
embryoid body14
blastocyst16
neonate225
fetus95
infant127
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue36.6
adrenal gland60.7
appendix39.2
bone marrow67
cerebral cortex33.5
colon25.5
duodenum18.2
esophagus44
gallbladder41.2
heart muscle14.9
kidney16.3
liver29.4
lung30.9
lymph node23.2
ovary26.3
pancreas13.3
placenta38.2
prostate23
salivary gland14.6
skin54.6
small intestine20
spleen23.6
stomach21.1
testis26.3
thyroid gland22.2
urinary bladder37
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607538, gene) Nde1-like 1; NDEL1OMIM


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