Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9GZV4)
Protein (NX_Q9GZV4)
Protein
Gene SymbolEIF5A2 to neXtProt (NX_Q9GZV4)
DescriptionEukaryotic translation initiation factor 5A-2
Chromosome3
Location3q26.2 (170606204 ~ 170626482) to Ensembl
Sequene Features : Isoforms 1, Variants 16, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mRNA transport
.positive regulation of translational termination
.positive regulation of translational elongation
  + 8 more...
.ribosome binding
.translation elongation factor activity
.cytosol
.endoplasmic reticulum membrane
.nuclear pore
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 16 2
2014-09-19protein level
1 13 2
2014-05-27protein level
1 13 11
2014-02-25protein level
1 13 12
2013-12-09protein level
1 12 12
2013-11-01protein level
1 12 11
2013-09-12protein level
1 12 10
2013-08-17protein level
1 12 10
2013-07-15protein level
1 6 5
2013-06-11protein level
1 6 5
2013-02-12protein level
1 2 7
2012-12-20protein level
1 2 7
2012-10-30protein level
1 2 7
2012-10-07protein level
1 2 7
2012-08-24protein level
1 2 7
2012-07-28protein level
1 2 7
2012-06-08protein level
1 2 7
2012-05-07protein level
1 2 7
2012-04-10protein level
1 2 7
2012-01-13protein level
1 1 7
2011-12-20protein level
1 1 7
2011-11-11protein level
1 1 5
2011-08-23protein level
1 1 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9GZV4-1
4 0 3 16782.1909
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-748028,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
2 EBI-748028,EBI-741925 DHPS  
  .protein homotetramerization
.deoxyhypusine biosynthetic process from spermidine
.cellular protein metabolic process
  + 6 more...
.deoxyhypusine synthase activity .cytosol
3 EBI-748028,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
4 EBI-748028,EBI-740897 NIF3L1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription, DNA-templated
.neuron differentiation
.identical protein binding
.transcription factor binding
.mitochondrion
.cytoplasm
.nucleus
5 EBI-748028,EBI-396137 CDC23  
  .protein K11-linked ubiquitination
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
.positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
  + 11 more...
.ubiquitin-protein transferase activity .cytosol
.anaphase-promoting complex
.nucleoplasm
.intracellular
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood32
bone27
brain21
connective tissue6
ear62
embryonic tissue4
eye14
kidney9
lung5
pancreas14
pharynx24
pituitary gland242
placenta24
prostate15
salivary gland49
skin28
stomach10
testis29
uterus25
vascular38
Health State
TissuesTPM*
normal18
germ cell tumor3
kidney tumor14
leukemia10
lung tumor9
non-neoplasia31
primitive neuroectodermal tumor of the CNS31
prostate cancer9
skin tumor47
soft tissue/muscle tissue tumor23
Developmental Stage
TissuesTPM*
adult14
fetus10
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.3
adrenal gland3.5
appendix4.2
bone marrow1.9
cerebral cortex3.9
colon2.7
duodenum2.5
esophagus2.1
gallbladder3.7
heart muscle4
kidney4.6
liver1.3
lung2.2
lymph node3.2
ovary4.8
pancreas2
placenta1.6
prostate3.1
salivary gland1.4
skin1.1
small intestine1.7
spleen2.2
stomach7.9
testis19.2
thyroid gland2.1
urinary bladder3.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605782, gene) Eukaryotic translation initiation factor 5a2; EIF5A2OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center