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> Protein (NX_Q9H0L4)
Protein (NX_Q9H0L4)
Protein
Gene SymbolCSTF2T to neXtProt (NX_Q9H0L4)
DescriptionCleavage stimulation factor subunit 2 tau variant
Chromosome10
Location10q21.1 (53455247 ~ 53459355) to Ensembl
Sequene Features : Isoforms 1, Variants 78, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mRNA processing .poly(A) RNA binding
.nucleotide binding
.nucleus
.intracellular
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 78 7
2014-09-19protein level
1 61 7
2014-05-27protein level
1 61 7
2014-02-25protein level
1 60 5
2013-12-09protein level
1 50 5
2013-11-01protein level
1 49 4
2013-09-12protein level
1 49 4
2013-08-17protein level
1 49 4
2013-07-15protein level
1 32 2
2013-06-11protein level
1 32 2
2013-02-12protein level
1 15 3
2012-12-20protein level
1 14 3
2012-10-30protein level
1 16 3
2012-10-07protein level
1 16 3
2012-08-24protein level
1 7 3
2012-07-28protein level
1 7 3
2012-06-08protein level
1 9 3
2012-05-07protein level
1 9 3
2012-04-10protein level
1 9 3
2012-01-13protein level
1 10 3
2011-12-20protein level
1 10 3
2011-11-11protein level
1 10 3
2011-08-23protein level
1 10 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H0L4-1
17 0 8 64395.3277
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-747012,EBI-740220 HGS  
  .positive regulation of exosomal secretion
.protein localization to membrane
.membrane organization
  + 13 more...
.metal ion binding
.protein domain specific binding
.extracellular exosome
.intracellular membrane-bounded organelle
.multivesicular body membrane
  + 6 more...
2 EBI-747012,EBI-741480 UBQLN1  
  .regulation of autophagic vacuole assembly
.positive regulation of ER-associated ubiquitin-dependent protein catabolic process
.regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
  + 8 more...
.identical protein binding
.polyubiquitin binding
.kinase binding
.perinuclear region of cytoplasm
.protein complex
.aggresome
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
bladder33
blood32
bone27
bone marrow20
brain75
cervix61
connective tissue13
embryonic tissue28
esophagus49
eye33
heart44
intestine51
kidney52
liver19
lung14
lymph node22
mammary gland26
mouth45
ovary39
pancreas23
parathyroid145
pharynx24
placenta21
prostate15
skin23
spleen131
stomach41
testis16
thymus100
trachea19
uterus43
vascular96
Health State
TissuesTPM*
normal46
bladder carcinoma56
breast (mammary gland) tumor21
cervical tumor86
chondrosarcoma12
colorectal tumor71
esophageal tumor57
gastrointestinal tumor25
germ cell tumor15
glioma27
head and neck tumor22
kidney tumor29
leukemia31
liver tumor20
lung tumor9
lymphoma55
non-neoplasia20
ovarian tumor52
primitive neuroectodermal tumor of the CNS31
retinoblastoma43
skin tumor31
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult28
blastocyst32
neonate32
fetus68
infant42
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.5
adrenal gland12.6
appendix17.3
bone marrow8.4
cerebral cortex16.6
colon11
duodenum10.6
esophagus9.1
gallbladder11
heart muscle11.3
kidney11.1
liver6.7
lung9.2
lymph node18.8
ovary16.8
pancreas5.9
placenta10.7
prostate11
salivary gland7.8
skin9.2
small intestine10.3
spleen16.1
stomach10.7
testis10.7
thyroid gland12.2
urinary bladder12.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611968, gene) Cleavage stimulation factor, 3-prime pre-rna, subunit 2, 64-kd, tauOMIM


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