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> Protein (NX_Q9H115)
Protein (NX_Q9H115)
Protein
Gene SymbolNAPB to neXtProt (NX_Q9H115)
DescriptionBeta-soluble NSF attachment protein
Chromosome20
Location20p11.21 (23355159 ~ 23402125) to Ensembl
Sequene Features : Isoforms 3, Variants 29, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane fusion
.SNARE complex disassembly
.intracellular protein transport
.syntaxin binding
.soluble NSF attachment protein activity
.extracellular exosome
.SNARE complex
.vacuolar membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 29 0
2014-09-19protein level
3 23 0
2014-05-27protein level
1 22 1
2014-02-25protein level
1 22 1
2013-12-09protein level
1 20 1
2013-11-01protein level
1 19 1
2013-09-12protein level
1 19 1
2013-08-17protein level
1 19 1
2013-07-15protein level
1 12 0
2013-06-11protein level
1 12 0
2013-02-12protein level
1 7 1
2012-12-20protein level
1 6 1
2012-10-30protein level
1 8 1
2012-10-07protein level
1 8 1
2012-08-24protein level
1 5 1
2012-07-28protein level
1 5 1
2012-06-08protein level
1 5 1
2012-05-07protein level
1 5 1
2012-04-10protein level
1 5 1
2012-01-13protein level
1 3 1
2011-12-20protein level
1 3 1
2011-11-11protein level
1 3 1
2011-08-23protein level
1 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H115-1
4 10 3 33535.3986
NX_Q9H115-2
1 10 3 29434.4516
NX_Q9H115-3
1 7 3 23387.7744
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3921185,EBI-745000 SNAP23  
  .membrane fusion
.membrane organization
.synaptic vesicle fusion to presynaptic membrane
  + 5 more...
.syntaxin binding
.SNAP receptor activity
.extracellular exosome
.synapse
.neuron projection
  + 8 more...
2 EBI-3921185,EBI-2853548 STX16  
  .Golgi ribbon formation
.vesicle docking
.retrograde transport, endosome to Golgi
  + 3 more...
.syntaxin binding
.SNAP receptor activity
.SNARE binding
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.Golgi cisterna
  + 11 more...
3 EBI-3921185,EBI-3916574 TFEC  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription from RNA polymerase II promoter
.cellular response to heat
.transcription corepressor activity
.transcription coactivator activity
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.cytoplasm
.nucleoplasm
4 EBI-3921185,EBI-2695795 STX6  
  .Golgi ribbon formation
.Golgi vesicle transport
.retrograde transport, endosome to Golgi
  + 4 more...
.syntaxin binding
.SNAP receptor activity
.perinuclear region of cytoplasm
.trans-Golgi network membrane
.SNARE complex
  + 6 more...
5 EBI-3921185,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
6 EBI-3921185,EBI-714206 STX5  
  .regulation of Golgi organization
.Golgi disassembly
.vesicle fusion with Golgi apparatus
  + 7 more...
.protein N-terminus binding
.SNAP receptor activity
.SNARE binding
.endoplasmic reticulum-Golgi intermediate compartment membrane
.vesicle
.SNARE complex
  + 5 more...
7 EBI-3921185,EBI-1394295 STX3  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.long-term synaptic potentiation
  + 7 more...
.arachidonic acid binding
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.neuron projection
.azurophil granule
  + 11 more...
8 EBI-3921185,EBI-714543 ARL6IP1  
  .cotranslational protein targeting to membrane .N/A .integral component of membrane
.membrane
.cytosol
.Sec61 translocon complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder200
blood8
bone27
brain666
cervix41
connective tissue13
embryonic tissue14
eye162
heart55
intestine25
kidney71
liver9
lung65
lymph node33
mammary gland26
mouth75
muscle28
nerve128
pancreas46
pituitary gland60
placenta35
prostate21
skin4
spleen18
testis39
thymus62
trachea231
uterus17
vascular19
Health State
TissuesTPM*
normal234
bladder carcinoma284
cervical tumor28
chondrosarcoma12
colorectal tumor35
germ cell tumor49
glioma37
head and neck tumor44
kidney tumor116
leukemia10
lung tumor9
non-neoplasia41
pancreatic tumor28
primitive neuroectodermal tumor of the CNS7
retinoblastoma129
uterine tumor22
Developmental Stage
TissuesTPM*
adult45
fetus96
infant85
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.8
adrenal gland26.7
appendix6.2
bone marrow7.5
cerebral cortex161.2
colon5.5
duodenum5.1
esophagus5.7
gallbladder6.2
heart muscle4.1
kidney5.7
liver2.9
lung5.8
lymph node6.4
ovary9.5
pancreas3.2
placenta7.9
prostate6.2
salivary gland4.4
skin6.4
small intestine8.2
spleen7.2
stomach6.5
testis9.6
thyroid gland8.8
urinary bladder5.8
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastLow
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisMedium
esophagusLow
fallopian tubeMedium
gallbladderMedium
heart muscleLow
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
nasopharynxMedium
oral mucosaLow
ovaryMedium
pancreasMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandLow
seminal vesicleMedium
skeletal muscleLow
skin 1Low
skin 2Low
small intestineMedium
smooth muscleLow
soft tissue 1Medium
soft tissue 2Low
stomach 1High
stomach 2High
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611270, gene) N-ethylmaleimide-sensitive factor attachment protein, beta; NAPBOMIM


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