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> Protein (NX_Q9H2B2)
Protein (NX_Q9H2B2)
Protein
Gene SymbolSYT4 to neXtProt (NX_Q9H2B2)
DescriptionSynaptotagmin-4
Chromosome18
Location18q12.3 (40847843 ~ 40857615) to Ensembl
Sequene Features : Isoforms 2, Variants 95, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of dendrite extension
.calcium ion-dependent exocytosis of neurotransmitter
.negative regulation of calcium ion-dependent exocytosis
  + 4 more...
.clathrin binding
.syntaxin binding
.calcium ion binding
.phosphatidylserine binding
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.neuron projection
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 95 0
2014-09-19protein level
1 67 0
2014-05-27protein level
1 67 0
2014-02-25protein level
1 65 0
2013-12-09protein level
1 60 0
2013-11-01protein level
1 53 0
2013-09-12protein level
1 53 0
2013-08-17protein level
1 53 0
2013-07-15protein level
1 44 0
2013-06-11protein level
1 44 0
2013-02-12protein level
1 17 0
2012-12-20protein level
1 18 0
2012-10-30protein level
1 19 0
2012-10-07protein level
1 19 0
2012-08-24protein level
1 11 0
2012-07-28protein level
1 11 0
2012-06-08protein level
1 11 0
2012-05-07protein level
1 10 0
2012-04-10protein level
1 10 0
2012-01-13protein level
1 3 0
2011-12-20protein level
1 3 0
2011-11-11protein level
1 3 0
2011-08-23protein level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H2B2-1
1 15 0 47927.8952
NX_Q9H2B2-2
1 15 0 46034.9079
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751132,EBI-347996 SGTA  
  .viral process .N/A .cytoplasm
2 EBI-751132,EBI-742698 NBR1  
  .protein oligomerization
.negative regulation of osteoblast differentiation
.regulation of stress-activated MAPK cascade
  + 2 more...
.mitogen-activated protein kinase binding
.ubiquitin binding
.zinc ion binding
.extracellular exosome
.M band
.cytoplasmic vesicle
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bone69
brain506
embryonic tissue9
eye14
kidney18
lung17
muscle65
nerve193
pancreas14
pituitary gland121
prostate31
stomach10
testis73
vascular19
Health State
TissuesTPM*
normal167
germ cell tumor151
kidney tumor58
lung tumor9
primitive neuroectodermal tumor of the CNS55
prostate cancer28
Developmental Stage
TissuesTPM*
adult31
embryoid body14
blastocyst16
fetus236
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland17.1
appendix1.7
cerebral cortex49.2
pancreas1.8
stomach4.4
testis1.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600103, gene) Synaptotagmin 4; SYT4OMIM


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