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> Protein (NX_Q9H2K8)
Protein (NX_Q9H2K8)
Protein
Gene SymbolTAOK3 to neXtProt (NX_Q9H2K8)
DescriptionSerine/threonine-protein kinase TAO3
Chromosome12
Location12q24.23 (118587606 ~ 118810750) to Ensembl
Sequene Features : Isoforms 1, Variants 109, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein autophosphorylation
.positive regulation of JNK cascade
.negative regulation of JNK cascade
  + 11 more...
.transferase activity
.ATP binding
.protein kinase inhibitor activity
  + 2 more...
.plasma membrane
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 109 6
2014-09-19protein level
1 85 6
2014-05-27protein level
1 85 6
2014-02-25protein level
1 84 5
2013-12-09protein level
1 71 5
2013-11-01protein level
1 67 5
2013-09-12protein level
1 67 7
2013-08-17protein level
1 67 7
2013-07-15protein level
1 46 5
2013-06-11protein level
1 46 5
2013-02-12protein level
1 19 6
2012-12-20protein level
1 18 6
2012-10-30protein level
1 22 6
2012-10-07protein level
1 22 6
2012-08-24protein level
1 14 6
2012-07-28protein level
1 14 6
2012-06-08protein level
1 22 6
2012-05-07protein level
1 22 6
2012-04-10protein level
1 22 6
2012-01-13protein level
1 19 6
2011-12-20protein level
1 19 6
2011-11-11protein level
1 19 7
2011-08-23protein level
1 17 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H2K8-1
30 0 4 105339.4219
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1384100,EBI-371750 ERN1  
  .peptidyl-serine trans-autophosphorylation
.insulin metabolic process
.positive regulation of endoplasmic reticulum unfolded protein response
  + 23 more...
.Hsp90 protein binding
.ADP binding
.protein homodimerization activity
  + 7 more...
.IRE1-RACK1-PP2A complex
.IRE1-TRAF2-ASK1 complex
.Ire1 complex
  + 6 more...
2 EBI-1384100,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites100
bladder33
blood81
bone marrow20
brain66
cervix61
connective tissue46
embryonic tissue14
eye57
heart44
intestine103
kidney56
larynx42
liver48
lung59
lymph node133
mammary gland52
mouth15
muscle37
nerve64
ovary19
pancreas42
parathyroid48
pharynx98
pituitary gland60
placenta24
prostate47
skin99
spleen93
stomach52
testis29
thymus138
thyroid42
tonsil117
uterus43
vascular19
Health State
TissuesTPM*
normal53
breast (mammary gland) tumor75
cervical tumor86
chondrosarcoma48
colorectal tumor133
gastrointestinal tumor50
germ cell tumor91
glioma37
head and neck tumor29
kidney tumor87
leukemia21
liver tumor52
lung tumor29
lymphoma27
non-neoplasia41
ovarian tumor26
pancreatic tumor19
primitive neuroectodermal tumor of the CNS15
prostate cancer38
retinoblastoma43
skin tumor39
soft tissue/muscle tissue tumor7
uterine tumor44
Developmental Stage
TissuesTPM*
adult52
embryoid body28
blastocyst16
neonate32
fetus39
infant85
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13.2
adrenal gland19.2
appendix26.3
bone marrow28.6
cerebral cortex33.4
colon23.6
duodenum24.8
esophagus18.9
gallbladder22.4
heart muscle15.1
kidney15.8
liver10.7
lung21.8
lymph node35.7
ovary19.4
pancreas5.9
placenta13.1
prostate27.5
salivary gland11.4
skin16.4
small intestine26.6
spleen26.3
stomach24
testis13.8
thyroid gland22.8
urinary bladder26.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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