Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9H4L4)
Protein (NX_Q9H4L4)
Protein
Gene SymbolSENP3 to neXtProt (NX_Q9H4L4)
DescriptionSentrin-specific protease 3
Chromosome17
Location17p13.1 (7465192 ~ 7475287) to Ensembl
Sequene Features : Isoforms 1, Variants 32, PTMs 10 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .cysteine-type peptidase activity .MLL1 complex
.cytoplasm
.nucleolus
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 32 10
2014-09-19protein level
1 17 10
2014-05-27protein level
1 17 10
2014-02-25protein level
1 17 10
2013-12-09protein level
1 11 10
2013-11-01protein level
1 11 9
2013-09-12protein level
1 11 9
2013-08-17protein level
1 11 9
2013-07-15protein level
1 7 8
2013-06-11protein level
1 7 8
2013-02-12protein level
1 3 11
2012-12-20protein level
1 5 11
2012-10-30protein level
1 5 11
2012-10-07protein level
1 5 11
2012-08-24protein level
1 5 11
2012-07-28protein level
1 5 11
2012-06-08protein level
1 14 11
2012-05-07protein level
1 12 11
2012-04-10protein level
1 12 11
2012-01-13protein level
1 14 11
2011-12-20protein level
1 14 11
2011-11-11protein level
1 14 11
2011-08-23protein level
1 14 11
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H4L4-1
24 0 0 64968.5026
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2880236,EBI-78579 NPM1  
  .regulation of eIF2 alpha phosphorylation by dsRNA
.regulation of endoribonuclease activity
.protein oligomerization
  + 20 more...
.unfolded protein binding
.NF-kappaB binding
.protein heterodimerization activity
  + 10 more...
.spindle pole centrosome
.ribonucleoprotein complex
.membrane
  + 7 more...
2 EBI-2880236,EBI-3390054 UBC  
  .programmed necrotic cell death
.apoptotic signaling pathway
.energy homeostasis
  + 90 more...
.poly(A) RNA binding
.protease binding
.extracellular exosome
.endocytic vesicle membrane
.endosome membrane
  + 3 more...
3 EBI-2880236,EBI-716449 PELP1  
  .cellular response to estrogen stimulus
.positive regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.poly(A) RNA binding
.transcription factor binding
.chromatin binding
.MLL1 complex
.transcriptionally active chromatin
.membrane
  + 4 more...
4 EBI-2880236,EBI-727429 WDR18  
  .multicellular organismal development .N/A .cytoplasm
.nucleoplasm
5 EBI-2880236,EBI-2371062 TEX10  
  .N/A .N/A .MLL1 complex
.nuclear membrane
.integral component of membrane
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
blood16
bone125
brain2
cervix20
connective tissue33
embryonic tissue28
eye14
heart33
intestine34
kidney33
liver4
lung5
lymph45
lymph node11
mammary gland39
mouth30
muscle9
nerve64
ovary19
pancreas4
parathyroid48
pituitary gland121
placenta3
prostate26
skin23
spleen18
stomach41
testis18
thyroid21
uterus17
Health State
TissuesTPM*
normal21
adrenal tumor79
breast (mammary gland) tumor64
cervical tumor57
chondrosarcoma156
colorectal tumor44
gastrointestinal tumor16
germ cell tumor7
glioma74
head and neck tumor29
kidney tumor14
leukemia52
lung tumor19
lymphoma69
non-neoplasia10
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS47
prostate cancer28
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult33
embryoid body14
blastocyst81
fetus5
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue20.7
adrenal gland26.7
appendix27.5
bone marrow23.5
cerebral cortex29.6
colon26.3
duodenum27
esophagus33
gallbladder29.3
heart muscle24.5
kidney24.1
liver10.3
lung30.9
lymph node36.8
ovary30.5
pancreas15
placenta28.7
prostate22
salivary gland27.2
skin34.3
small intestine25.7
spleen26.1
stomach19.9
testis39.1
thyroid gland35.6
urinary bladder32.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612844, gene) Sentrin-specific protease family, member 3; SENP3OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2020 (C) Yonsei Proteome Research Center