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> Protein (NX_Q9H5Z6)
Protein (NX_Q9H5Z6)
Protein
Gene SymbolFAM124B to neXtProt (NX_Q9H5Z6)
DescriptionProtein FAM124B
Chromosome2
Location2q36.2 (225243415 ~ 225266802) to Ensembl
Sequene Features : Isoforms 2, Variants 63, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 63 0
2014-09-19protein level
2 52 0
2014-05-27protein level
2 52 0
2014-02-25protein level
2 50 0
2013-12-09protein level
2 35 0
2013-11-01protein level
2 34 0
2013-09-12protein level
2 34 0
2013-08-17protein level
2 34 0
2013-07-15protein level
2 24 0
2013-06-11protein level
2 24 0
2013-02-12protein level
2 11 2
2012-12-20protein level
2 12 2
2012-10-30protein level
2 17 2
2012-10-07protein level
2 17 1
2012-08-24protein level
2 13 1
2012-07-28protein level
2 13 1
2012-06-08protein level
2 16 1
2012-05-07protein level
2 16 1
2012-04-10protein level
2 16 1
2012-01-13protein level
2 8 1
2011-12-20protein level
2 8 1
2011-11-11protein level
2 8 1
2011-08-23protein level
2 8 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H5Z6-1
10 14 0 50928.491
NX_Q9H5Z6-2
2 14 0 31255.5295
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741626,EBI-742756 KRT19  
  .cell differentiation involved in embryonic placenta development
.sarcomere organization
.response to estrogen
.viral process
.structural constituent of muscle
.structural constituent of cytoskeleton
.cell periphery
.extracellular exosome
.costamere
  + 5 more...
2 EBI-741626,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
3 EBI-741626,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
4 EBI-741626,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
5 EBI-741626,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
6 EBI-741626,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
7 EBI-741626,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
8 EBI-741626,EBI-2340269 MKRN3  
  .protein ubiquitination .ligase activity
.zinc ion binding
.ribonucleoprotein complex
9 EBI-741626,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
10 EBI-741626,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
11 EBI-741626,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
12 EBI-741626,EBI-10173507 ADAMTSL4  
  .cellular protein metabolic process
.post-translational protein modification
.positive regulation of apoptotic process
  + 4 more...
.metalloendopeptidase activity
.protease binding
.endoplasmic reticulum lumen
.interstitial matrix
13 EBI-741626,EBI-4397613 KCTD9  
  .protein homooligomerization .N/A .N/A
14 EBI-741626,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
15 EBI-741626,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
16 EBI-741626,EBI-10181113 KIAA1958  
  .N/A .N/A .N/A
17 EBI-741626,EBI-2511344 KCTD6  
  .protein homooligomerization .ankyrin binding .N/A
18 EBI-741626,EBI-740322 RBPMS  
  .positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
19 EBI-741626,EBI-517623 BIRC7  
  .inhibition of cysteine-type endopeptidase activity involved in apoptotic process
.regulation of natural killer cell apoptotic process
.negative regulation of apoptotic process
  + 4 more...
.cysteine-type endopeptidase inhibitor activity involved in apoptotic process
.enzyme binding
.ligase activity
  + 3 more...
.Golgi apparatus
.cytoplasm
.nucleus
20 EBI-741626,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
21 EBI-741626,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
22 EBI-741626,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
23 EBI-741626,EBI-751319 CARD9  
  .nucleotide-binding oligomerization domain containing signaling pathway
.defense response to virus
.defense response to Gram-positive bacterium
  + 17 more...
.CARD domain binding
.protein homodimerization activity
.plasma membrane
.cytosol
.cytoplasm
24 EBI-741626,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone marrow20
brain4
mouth30
muscle37
pharynx24
placenta31
skin4
umbilical cord72
vascular271
Health State
TissuesTPM*
normal10
leukemia10
Developmental Stage
TissuesTPM*
adult6
neonate32
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.2
appendix1.1
bone marrow2.8
colon1.1
esophagus1.2
gallbladder1.4
heart muscle1.1
lung2.2
placenta6.6
skin1
thyroid gland1
urinary bladder2.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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