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> Protein (NX_Q9H6L2)
Protein (NX_Q9H6L2)
Protein
Gene SymbolTMEM231 to neXtProt (NX_Q9H6L2)
DescriptionTransmembrane protein 231
Chromosome16
Location16q23.1 (75572015 ~ 75590184) to Ensembl
Sequene Features : Isoforms 3, Variants 27, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cilium assembly
.smoothened signaling pathway
.N/A .ciliary membrane
.TCTN-B9D complex
.ciliary transition zone
.integral component of membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 27 4
2014-09-19protein level
3 23 4
2014-05-27protein level
3 22 4
2014-02-25protein level
3 22 4
2013-12-09protein level
3 13 4
2013-11-01protein level
3 13 4
2013-09-12protein level
3 13 4
2013-08-17protein level
3 13 4
2013-07-15protein level
3 12 3
2013-06-11protein level
3 12 3
2013-02-12protein level
3 8 9
2012-12-20protein level
3 6 9
2012-10-30protein level
3 8 9
2012-10-07protein level
3 8 3
2012-08-24transcript level
3 7 3
2012-07-28transcript level
3 6 3
2012-06-08transcript level
3 8 3
2012-05-07transcript level
3 8 3
2012-04-10transcript level
3 8 3
2012-01-13transcript level
1 2 3
2011-12-20transcript level
1 2 3
2011-11-11transcript level
1 2 3
2011-08-23transcript level
1 2 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H6L2-1
2 11 0 36035.7536
NX_Q9H6L2-2
3 11 0 39092.1255
NX_Q9H6L2-3
0 9 0 22850.9049
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10307654,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
2 EBI-10307654,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
3 EBI-10307654,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
bone13
brain52
cervix20
connective tissue73
ear124
embryonic tissue23
eye33
heart11
intestine25
kidney33
liver9
lung35
lymph90
lymph node44
mammary gland19
mouth15
muscle9
ovary29
pancreas4
placenta10
prostate10
skin37
testis105
trachea135
uterus21
vascular38
Health State
TissuesTPM*
normal35
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma12
colorectal tumor8
gastrointestinal tumor8
germ cell tumor53
glioma46
head and neck tumor7
kidney tumor14
leukemia42
liver tumor20
lung tumor9
lymphoma55
non-neoplasia41
ovarian tumor26
primitive neuroectodermal tumor of the CNS55
prostate cancer9
retinoblastoma43
skin tumor15
soft tissue/muscle tissue tumor71
uterine tumor22
Developmental Stage
TissuesTPM*
adult29
embryoid body28
blastocyst32
neonate64
fetus44
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4
adrenal gland5.4
appendix2.9
bone marrow1.2
cerebral cortex10.1
colon5.3
duodenum4.8
esophagus5.6
gallbladder5.9
heart muscle7.4
kidney6.5
liver1.2
lung10
lymph node2.6
ovary10.9
pancreas1.9
placenta3.7
prostate7.5
salivary gland1.7
skin3.6
small intestine3.5
spleen3.1
stomach4.4
testis13
thyroid gland12.4
urinary bladder4.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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