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> Protein (NX_Q9H6L4)
Protein (NX_Q9H6L4)
Protein
Gene SymbolARMC7 to neXtProt (NX_Q9H6L4)
DescriptionArmadillo repeat-containing protein 7
Chromosome17
Location17q25.1 (73106047 ~ 73126360) to Ensembl
Sequene Features : Isoforms 2, Variants 29, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 29 1
2014-09-19protein level
1 21 1
2014-05-27protein level
1 20 1
2014-02-25protein level
1 21 1
2013-12-09protein level
1 14 1
2013-11-01protein level
1 14 1
2013-09-12protein level
1 14 1
2013-08-17protein level
1 14 1
2013-07-15protein level
1 11 1
2013-06-11protein level
1 11 1
2013-02-12protein level
1 7 1
2012-12-20protein level
1 6 1
2012-10-30protein level
1 8 1
2012-10-07protein level
1 8 1
2012-08-24protein level
1 8 1
2012-07-28protein level
1 8 1
2012-06-08protein level
1 7 1
2012-05-07protein level
1 7 1
2012-04-10protein level
1 7 1
2012-01-13protein level
1 3 1
2011-12-20protein level
1 3 1
2011-11-11transcript level
1 3 0
2011-08-23transcript level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H6L4-1
6 2 0 21910.1939
NX_Q9H6L4-2
2 2 0 11409.3883
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-742909,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-742909,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
3 EBI-742909,EBI-6509505 INCA1  
  .positive regulation of apoptotic signaling pathway
.negative regulation of cyclin-dependent protein serine/threonine kinase activity
.negative regulation of cell proliferation
.cyclin binding
.cyclin-dependent protein serine/threonine kinase inhibitor activity
.cytoplasm
.nucleus
4 EBI-742909,EBI-745305 IKZF1  
  .retina development in camera-type eye
.positive regulation of NK T cell differentiation
.Peyer's patch development
  + 17 more...
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.protein complex
.cytoplasm
.pericentric heterochromatin
.nucleus
5 EBI-742909,EBI-2505861 TNFAIP1  
  .protein homooligomerization
.positive regulation of DNA replication
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 8 more...
.GTP-Rho binding .Cul3-RING ubiquitin ligase complex
.endosome
.cytoplasm
.nucleolus
6 EBI-742909,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
7 EBI-742909,EBI-358410 CPSF6  
  .protein tetramerization
.mRNA processing
.mRNA polyadenylation
.poly(A) RNA binding
.mRNA binding
.nucleotide binding
.paraspeckles
.ribonucleoprotein complex
.membrane
  + 3 more...
8 EBI-742909,EBI-747225 RUNDC3A  
  .small GTPase mediated signal transduction .GTPase regulator activity
.guanylate cyclase activator activity
.plasma membrane
.cytosol
9 EBI-742909,EBI-2349927 EFHC2  
  .N/A .calcium ion binding .N/A
10 EBI-742909,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
11 EBI-742909,EBI-746909 CPSF7  
  .protein tetramerization
.mRNA 3'-end processing
.gene expression
  + 4 more...
.poly(A) RNA binding
.nucleotide binding
.membrane
.mRNA cleavage factor complex
.nucleoplasm
.nucleus
12 EBI-742909,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
13 EBI-742909,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
14 EBI-742909,EBI-372911 SPATC1L  
  .N/A .N/A .N/A
15 EBI-742909,EBI-743598 ABI2  
  .positive regulation of Arp2/3 complex-mediated actin nucleation
.peptidyl-tyrosine phosphorylation
.Rac protein signal transduction
  + 5 more...
.proline-rich region binding
.protein complex binding
.ubiquitin protein ligase binding
  + 4 more...
.SCAR complex
.filopodium
.lamellipodium
  + 3 more...
16 EBI-742909,EBI-742038 ABI3  
  .regulation of cell migration
.movement of cell or subcellular component
.N/A .lamellipodium
.membrane
.cytoplasm
.intracellular
17 EBI-742909,EBI-747204 IKZF3  
  .regulation of lymphocyte differentiation
.regulation of B cell differentiation
.regulation of apoptotic process
  + 5 more...
.protein heterodimerization activity
.metal ion binding
.sequence-specific DNA binding
  + 2 more...
.plasma membrane
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites552
bladder33
blood24
bone27
bone marrow20
brain31
cervix82
connective tissue26
embryonic tissue18
esophagus148
eye38
heart22
intestine21
kidney61
liver9
lung41
lymph45
mammary gland13
muscle18
ovary49
pancreas4
placenta28
prostate58
salivary gland98
skin33
spleen74
stomach10
testis13
thymus62
uterus17
Health State
TissuesTPM*
normal36
breast (mammary gland) tumor10
chondrosarcoma36
colorectal tumor8
esophageal tumor173
gastrointestinal tumor185
germ cell tumor56
glioma93
kidney tumor14
leukemia10
lung tumor19
lymphoma27
non-neoplasia31
ovarian tumor39
pancreatic tumor9
primitive neuroectodermal tumor of the CNS86
prostate cancer9
skin tumor39
soft tissue/muscle tissue tumor31
uterine tumor22
Developmental Stage
TissuesTPM*
adult39
blastocyst32
neonate96
fetus25
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.3
adrenal gland3.3
appendix5.6
bone marrow2.5
cerebral cortex4.7
colon8.6
duodenum8.3
esophagus4
gallbladder5
heart muscle4.8
kidney10.1
liver5.4
lung8.8
lymph node6.5
ovary3.5
pancreas2.5
placenta5.7
prostate6.9
salivary gland5.3
skin6.3
small intestine7.4
spleen7.7
stomach9.7
testis4.4
thyroid gland7.3
urinary bladder6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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