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> Protein (NX_Q9H867)
Protein (NX_Q9H867)
Protein
Gene SymbolVCPKMT to neXtProt (NX_Q9H867)
DescriptionProtein-lysine methyltransferase METTL21D
Chromosome14
Location14q21.3 (50575350 ~ 50583318) to Ensembl
Sequene Features : Isoforms 5, Variants 10, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.peptidyl-lysine trimethylation .protein-lysine N-methyltransferase activity .cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 10 2
2014-09-19protein level
5 15 2
2014-05-27protein level
5 15 2
2014-02-25protein level
5 15 2
2013-12-09protein level
5 9 2
2013-11-01protein level
5 8 2
2013-09-12protein level
5 8 1
2013-08-17protein level
5 8 1
2013-07-15protein level
5 4 0
2013-06-11protein level
5 4 0
2013-02-12protein level
5 4 0
2012-12-20protein level
5 3 0
2012-10-30transcript level
5 5 0
2012-10-07transcript level
5 5 0
2012-08-24transcript level
5 5 0
2012-07-28transcript level
5 6 0
2012-06-08transcript level
5 1 0
2012-05-07transcript level
5 1 0
2012-04-10transcript level
4 1 0
2012-01-13transcript level
4 1 0
2011-12-20transcript level
4 4 0
2011-11-11transcript level
4 4 0
2011-08-23transcript level
4 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H867-1
0 5 0 15555.0628
NX_Q9H867-2
2 3 0 14201.0677
NX_Q9H867-3
1 3 0 9364.7694
NX_Q9H867-4
2 7 0 25790.0224
NX_Q9H867-5
0 7 0 21420.7238
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood139
bone27
brain18
connective tissue13
ear62
embryonic tissue28
esophagus49
eye23
heart11
intestine12
kidney37
liver34
lung14
lymph node89
mammary gland6
mouth15
muscle18
pancreas56
parathyroid97
pituitary gland60
placenta7
prostate10
salivary gland49
skin4
testis34
thymus12
thyroid42
uterus34
Health State
TissuesTPM*
normal21
breast (mammary gland) tumor10
chondrosarcoma12
esophageal tumor57
germ cell tumor18
head and neck tumor22
kidney tumor29
leukemia158
liver tumor62
lymphoma13
non-neoplasia10
pancreatic tumor9
prostate cancer9
retinoblastoma64
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor55
Developmental Stage
TissuesTPM*
adult14
embryoid body28
blastocyst32
fetus16
juvenile125
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.1
adrenal gland6.6
appendix8.8
bone marrow14.8
cerebral cortex5.3
colon4.6
duodenum5.3
esophagus6
gallbladder5.3
heart muscle2.8
kidney4.3
liver2.9
lung5.9
lymph node9.8
ovary4.6
pancreas2.2
placenta4.1
prostate5.5
salivary gland2.6
skin8.8
small intestine7.5
spleen7.6
stomach5.8
testis8.1
thyroid gland5.3
urinary bladder5.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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