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> Protein (NX_Q9H8E8)
Protein (NX_Q9H8E8)
Protein
Gene SymbolCSRP2BP to neXtProt (NX_Q9H8E8)
DescriptionCysteine-rich protein 2-binding protein
Chromosome20
Location20p11.23 (18118762 ~ 18169031) to Ensembl
Sequene Features : Isoforms 2, Variants 110, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.histone H3 acetylation
.chromatin organization
.G2/M transition of mitotic cell cycle
.LIM domain binding
.histone acetyltransferase activity
.cytoplasm
.Ada2/Gcn5/Ada3 transcription activator complex
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 110 2
2014-09-19protein level
2 82 2
2014-05-27protein level
2 82 2
2014-02-25protein level
2 82 1
2013-12-09protein level
2 60 1
2013-11-01protein level
2 59 1
2013-09-12protein level
2 59 1
2013-08-17protein level
2 59 1
2013-07-15protein level
2 34 1
2013-06-11protein level
2 34 1
2013-02-12protein level
2 17 4
2012-12-20protein level
2 19 4
2012-10-30protein level
2 22 4
2012-10-07protein level
2 22 2
2012-08-24protein level
2 22 2
2012-07-28protein level
2 22 2
2012-06-08protein level
2 23 2
2012-05-07protein level
2 16 2
2012-04-10protein level
2 16 2
2012-01-13protein level
2 11 2
2011-12-20protein level
2 11 2
2011-11-11protein level
2 11 2
2011-08-23protein level
2 11 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H8E8-1
5 29 0 88787.4633
NX_Q9H8E8-2
1 29 0 74276.8384
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-750907,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-750907,EBI-741953 MBIP  
  .histone H3 acetylation
.chromatin organization
.inactivation of MAPK activity involved in osmosensory signaling pathway
.identical protein binding
.protein kinase inhibitor activity
.cytoplasm
.nucleolus
.Ada2/Gcn5/Ada3 transcription activator complex
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
blood24
bone13
bone marrow20
brain19
cervix41
embryonic tissue14
eye43
intestine25
kidney18
liver14
lung38
lymph node11
muscle9
ovary9
pancreas65
parathyroid97
placenta10
prostate21
skin4
testis16
thymus12
uterus8
Health State
TissuesTPM*
normal12
cervical tumor57
chondrosarcoma60
colorectal tumor8
gastrointestinal tumor8
germ cell tumor15
glioma37
leukemia31
liver tumor20
lung tumor38
non-neoplasia51
ovarian tumor13
pancreatic tumor123
primitive neuroectodermal tumor of the CNS7
prostate cancer9
retinoblastoma150
skin tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult16
embryoid body28
blastocyst16
fetus10
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.2
adrenal gland8.2
appendix5.5
bone marrow1.6
cerebral cortex10.6
colon9
duodenum10.7
esophagus7.6
gallbladder6.5
heart muscle6.6
kidney9.6
liver4.7
lung5.4
lymph node7.9
ovary11.5
pancreas3.7
placenta10.2
prostate7.1
salivary gland6
skin8.2
small intestine9.1
spleen7.8
stomach12.9
testis10.4
thyroid gland10.1
urinary bladder6.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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