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> Protein (NX_Q9H8V3)
Protein (NX_Q9H8V3)
Protein
Gene SymbolECT2 to neXtProt (NX_Q9H8V3)
DescriptionProtein ECT2
Chromosome3
Location3q26.31 (172468472 ~ 172539264) to Ensembl
Sequene Features : Isoforms 4, Variants 106, PTMs 15 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.apoptotic signaling pathway
.activation of GTPase activity
.cellular response to ionizing radiation
  + 19 more...
.protein homodimerization activity
.GTPase activator activity
.Rho guanyl-nucleotide exchange factor activity
.signal transducer activity
.centralspindlin complex
.mitotic spindle
.intracellular membrane-bounded organelle
  + 8 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 106 15
2014-09-19protein level
4 75 15
2014-05-27protein level
4 75 15
2014-02-25protein level
4 75 15
2013-12-09protein level
4 69 15
2013-11-01protein level
4 66 15
2013-09-12protein level
4 66 14
2013-08-17protein level
4 66 14
2013-07-15protein level
4 40 14
2013-06-11protein level
4 40 14
2013-02-12protein level
3 24 32
2012-12-20protein level
3 23 32
2012-10-30protein level
3 27 32
2012-10-07protein level
3 27 11
2012-08-24protein level
3 24 11
2012-07-28protein level
3 23 11
2012-06-08protein level
3 17 11
2012-05-07protein level
3 17 11
2012-04-10protein level
3 17 11
2012-01-13protein level
3 17 11
2011-12-20protein level
3 22 11
2011-11-11protein level
3 22 10
2011-08-23protein level
2 9 9
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H8V3-1
0 47 0 103438.8987
NX_Q9H8V3-2
1 44 0 99857.9445
NX_Q9H8V3-3
3 46 0 108460.3695
NX_Q9H8V3-4
0 45 0 99986.9868
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1054039,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
2 EBI-1054039,EBI-717233 RACGAP1  
  .regulation of attachment of spindle microtubules to kinetochore
.mitotic spindle midzone assembly
.regulation of small GTPase mediated signal transduction
  + 12 more...
.beta-tubulin binding
.metal ion binding
.gamma-tubulin binding
  + 5 more...
.centralspindlin complex
.mitotic spindle
.extracellular exosome
  + 9 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites200
bladder133
blood16
bone13
bone marrow123
brain23
cervix82
connective tissue46
embryonic tissue84
esophagus198
eye28
heart11
intestine103
kidney28
larynx42
liver24
lung26
lymph node89
mammary gland112
mouth241
muscle9
nerve128
ovary9
pancreas9
parathyroid48
pharynx24
placenta17
prostate10
salivary gland98
skin33
stomach31
testis101
thymus87
thyroid64
trachea96
uterus30
Health State
TissuesTPM*
normal22
adrenal tumor79
bladder carcinoma227
breast (mammary gland) tumor96
cervical tumor115
chondrosarcoma60
colorectal tumor159
esophageal tumor231
gastrointestinal tumor109
germ cell tumor132
glioma37
head and neck tumor156
kidney tumor58
leukemia52
liver tumor52
lung tumor38
lymphoma55
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
prostate cancer9
retinoblastoma129
skin tumor31
soft tissue/muscle tissue tumor47
uterine tumor22
Developmental Stage
TissuesTPM*
adult47
embryoid body28
blastocyst146
neonate96
fetus28
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.2
adrenal gland3.5
appendix8.9
bone marrow11.7
cerebral cortex4.8
colon12.9
duodenum9.9
esophagus9.1
gallbladder5.7
heart muscle2.6
kidney4.2
liver1.7
lung4.7
lymph node10.5
ovary1
pancreas1.2
placenta8.6
prostate3.6
salivary gland2.7
skin5.4
small intestine7.5
spleen3.8
stomach10.3
testis16.2
thyroid gland3.7
urinary bladder10.2
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*600586, gene) Epithelial cell transforming sequence 2 oncogene; ECT2OMIM


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