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> Protein (NX_Q9H9G7)
Protein (NX_Q9H9G7)
Protein
Gene SymbolAGO3 to neXtProt (NX_Q9H9G7)
DescriptionProtein argonaute-3
Chromosome1
Location1p34.3 (36396319 ~ 36538101) to Ensembl
Sequene Features : Isoforms 2, Variants 6, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of stem cell proliferation
.phosphatidylinositol-mediated signaling
.neurotrophin TRK receptor signaling pathway
  + 13 more...
.pre-miRNA binding
.poly(A) RNA binding
.miRNA binding
  + 2 more...
.RISC-loading complex
.micro-ribonucleoprotein complex
.RISC complex
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 6 1
2014-09-19protein level
2 58 1
2014-05-27protein level
2 58 2
2014-02-25protein level
2 57 2
2013-12-09protein level
2 53 2
2013-11-01protein level
2 49 2
2013-09-12protein level
2 49 1
2013-08-17protein level
2 49 1
2013-07-15protein level
2 28 0
2013-06-11protein level
2 28 0
2013-02-12protein level
2 12 0
2012-12-20protein level
2 12 0
2012-10-30protein level
2 11 0
2012-10-07protein level
2 11 0
2012-08-24protein level
2 10 0
2012-07-28protein level
2 10 0
2012-06-08protein level
2 11 0
2012-05-07protein level
2 2 0
2012-04-10protein level
2 2 0
2012-01-13protein level
2 6 0
2011-12-20protein level
2 6 0
2011-11-11protein level
2 6 0
2011-08-23protein level
2 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9H9G7-1
10 16 15 97297.713
NX_Q9H9G7-2
1 16 13 71165.1554
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2267883,EBI-358808 IPO8  
  .gene expression
.signal transduction
.intracellular protein transport
.Ran GTPase binding .cytosol
.nucleoplasm
2 EBI-2267883,EBI-2269715 TNRC6A  
  .phosphatidylinositol-mediated signaling
.neurotrophin TRK receptor signaling pathway
.innate immune response
  + 9 more...
.poly(A) RNA binding
.nucleotide binding
.micro-ribonucleoprotein complex
.cytosol
.nucleoplasm
.cytoplasmic mRNA processing body
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
bladder33
blood16
bone27
brain5
connective tissue13
embryonic tissue18
heart11
intestine4
kidney14
liver4
lung2
lymph22
lymph node66
mammary gland13
mouth15
muscle9
pancreas32
placenta10
prostate5
skin9
stomach31
testis34
thymus37
thyroid21
trachea38
uterus8
vascular19
Health State
TissuesTPM*
normal11
breast (mammary gland) tumor10
chondrosarcoma24
colorectal tumor8
gastrointestinal tumor42
germ cell tumor26
glioma9
head and neck tumor14
leukemia10
lymphoma13
non-neoplasia10
pancreatic tumor57
primitive neuroectodermal tumor of the CNS31
prostate cancer9
skin tumor15
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult13
embryoid body28
blastocyst16
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.3
adrenal gland4.3
appendix6.2
bone marrow9.1
cerebral cortex2.9
colon3.1
duodenum2.8
esophagus3.6
gallbladder4.2
heart muscle2.8
kidney3.7
liver2.5
lung4
lymph node5.1
ovary4.6
pancreas3
placenta6.1
prostate3.7
salivary gland1.9
skin3.4
small intestine2.5
spleen3.8
stomach3.9
testis12.3
thyroid gland4.9
urinary bladder4.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607355, gene) Eukaryotic translation initiation factor 2c, subunit 3; EIF2C3OMIM


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