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> Protein (NX_Q9HAF1)
Protein (NX_Q9HAF1)
Protein
Gene SymbolMEAF6 to neXtProt (NX_Q9HAF1)
DescriptionChromatin modification-related protein MEAF6
Chromosome1
Location1p34.3 (37958176 ~ 37980375) to Ensembl
Sequene Features : Isoforms 4, Variants 26, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.histone H3-K14 acetylation
.histone H4-K12 acetylation
.histone H4-K8 acetylation
  + 5 more...
.N/A .MOZ/MORF histone acetyltransferase complex
.NuA4 histone acetyltransferase complex
.centrosome
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 26 8
2014-09-19protein level
4 22 8
2014-05-27protein level
4 22 8
2014-02-25protein level
4 22 6
2013-12-09protein level
4 18 6
2013-11-01protein level
4 16 5
2013-09-12protein level
4 16 5
2013-08-17protein level
4 16 5
2013-07-15protein level
3 8 4
2013-06-11protein level
3 8 4
2013-02-12protein level
3 2 24
2012-12-20protein level
3 2 24
2012-10-30protein level
3 2 24
2012-10-07protein level
3 2 8
2012-08-24protein level
3 0 8
2012-07-28protein level
3 0 8
2012-06-08protein level
3 2 8
2012-05-07protein level
3 2 8
2012-04-10protein level
3 2 8
2012-01-13protein level
3 2 8
2011-12-20protein level
3 3 8
2011-11-11protein level
3 3 8
2011-08-23protein level
3 3 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9HAF1-1
0 6 0 21621.8168
NX_Q9HAF1-2
1 6 0 21611.4994
NX_Q9HAF1-3
1 6 0 22741.1888
NX_Q9HAF1-4
1 6 0 21695.7532
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-399266,EBI-740738 LDOC1  
  .negative regulation of cell proliferation .N/A .nucleolus
.nucleus
2 EBI-399266,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
3 EBI-399266,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
4 EBI-399266,EBI-742388 PLEKHF2  
  .protein transport .metal ion binding .early endosome membrane
.transport vesicle
.endoplasmic reticulum
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
bladder133
blood8
bone111
bone marrow41
brain97
cervix144
connective tissue46
ear124
embryonic tissue70
esophagus99
eye114
heart33
intestine47
kidney47
liver77
lung98
lymph45
lymph node77
mammary gland66
muscle94
nerve64
ovary49
pancreas117
pituitary gland60
placenta84
prostate116
salivary gland197
skin33
spleen18
stomach20
testis71
thymus50
thyroid21
tonsil58
trachea19
uterus77
vascular503
Health State
TissuesTPM*
normal82
bladder carcinoma113
breast (mammary gland) tumor42
cervical tumor86
chondrosarcoma108
colorectal tumor26
esophageal tumor115
gastrointestinal tumor42
germ cell tumor75
glioma74
kidney tumor72
leukemia21
liver tumor114
lung tumor9
lymphoma41
non-neoplasia31
ovarian tumor52
pancreatic tumor104
primitive neuroectodermal tumor of the CNS125
prostate cancer125
retinoblastoma107
skin tumor15
soft tissue/muscle tissue tumor39
uterine tumor77
Developmental Stage
TissuesTPM*
adult71
embryoid body71
blastocyst32
fetus82
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue29.9
adrenal gland44.8
appendix33.9
bone marrow32
cerebral cortex47.9
colon34.6
duodenum31.4
esophagus40
gallbladder48.1
heart muscle35.5
kidney34.2
liver34.4
lung44.8
lymph node46.1
ovary55.4
pancreas20.4
placenta34
prostate90.8
salivary gland30.5
skin37.7
small intestine33.8
spleen42
stomach34.8
testis67
thyroid gland49
urinary bladder49.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611001, gene) Chromosome 1 open reading frame 149; C1ORF149OMIM


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