Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9HB09)
Protein (NX_Q9HB09)
Protein
Gene SymbolBCL2L12 to neXtProt (NX_Q9HB09)
DescriptionBcl-2-like protein 12
Chromosome19
Location19q13.33 (50168823 ~ 50177173) to Ensembl
Sequene Features : Isoforms 3, Variants 51, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of cellular senescence
.inhibition of cysteine-type endopeptidase activity involved in apoptotic process
.negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.positive regulation of transcription from RNA polymerase II promoter
.N/A .membrane
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 51 7
2014-09-19protein level
3 36 7
2014-05-27protein level
3 32 7
2014-02-25protein level
3 32 6
2013-12-09protein level
3 21 6
2013-11-01protein level
3 18 6
2013-09-12protein level
3 18 6
2013-08-17protein level
3 18 7
2013-07-15protein level
3 17 6
2013-06-11protein level
3 17 6
2013-02-12protein level
3 12 20
2012-12-20protein level
3 13 13
2012-10-30protein level
3 14 13
2012-10-07protein level
3 14 6
2012-08-24protein level
3 14 6
2012-07-28protein level
3 14 6
2012-06-08protein level
3 15 6
2012-05-07protein level
3 13 6
2012-04-10protein level
2 13 6
2012-01-13protein level
2 5 6
2011-12-20protein level
2 5 6
2011-11-11protein level
2 5 6
2011-08-23protein level
2 5 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9HB09-1
2 16 0 36798.1709
NX_Q9HB09-2
5 4 0 19120.8904
NX_Q9HB09-3
1 16 0 36642.0704
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6969019,EBI-629985 HSPA1A  
  .N/A .N/A .N/A
2 EBI-6968951,EBI-3390054 UBC  
  .programmed necrotic cell death
.apoptotic signaling pathway
.energy homeostasis
  + 90 more...
.poly(A) RNA binding
.protease binding
.extracellular exosome
.endocytic vesicle membrane
.endosome membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites100
bladder33
blood32
bone153
brain22
cervix41
connective tissue33
embryonic tissue75
esophagus49
eye19
heart78
intestine73
kidney23
liver24
lung44
lymph45
lymph node356
mammary gland66
mouth45
muscle65
ovary39
pancreas37
placenta74
prostate52
skin33
spleen374
stomach73
testis9
thymus426
trachea57
uterus68
Health State
TissuesTPM*
normal55
bladder carcinoma56
breast (mammary gland) tumor64
cervical tumor57
chondrosarcoma96
colorectal tumor26
gastrointestinal tumor101
germ cell tumor56
glioma46
head and neck tumor14
kidney tumor29
leukemia10
liver tumor10
lung tumor19
lymphoma41
non-neoplasia31
pancreatic tumor66
primitive neuroectodermal tumor of the CNS7
prostate cancer28
skin tumor47
soft tissue/muscle tissue tumor87
uterine tumor11
Developmental Stage
TissuesTPM*
adult39
embryoid body14
blastocyst179
fetus46
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.6
adrenal gland4.5
appendix12
bone marrow9.6
cerebral cortex1.6
colon8.2
duodenum7.2
esophagus4.4
gallbladder6.5
heart muscle4.9
kidney5.5
liver6.3
lung6.4
lymph node13.4
ovary6.2
pancreas3.7
placenta9.5
prostate8.1
salivary gland6.1
skin4
small intestine8.1
spleen9.5
stomach7
testis6.1
thyroid gland3.2
urinary bladder5.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610837, gene) Bcl2-like 12; BCL2L12OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2020 (C) Yonsei Proteome Research Center