Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9HBL0)
Protein (NX_Q9HBL0)
Protein
Gene SymbolTNS1 to neXtProt (NX_Q9HBL0)
DescriptionTensin-1
Chromosome2
Location2q35 (218664512 ~ 218867718) to Ensembl
Sequene Features : Isoforms 2, Variants 299, PTMs 39 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.fibroblast migration
.cell-substrate junction assembly
.poly(A) RNA binding .cell surface
.focal adhesion
.cytoskeleton
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 299 39
2014-09-19protein level
1 232 39
2014-05-27protein level
1 232 39
2014-02-25protein level
1 231 39
2013-12-09protein level
1 172 39
2013-11-01protein level
1 164 39
2013-09-12protein level
1 164 39
2013-08-17protein level
1 164 39
2013-07-15protein level
1 123 39
2013-06-11protein level
1 123 39
2013-02-12protein level
1 71 32
2012-12-20protein level
1 70 32
2012-10-30protein level
1 84 32
2012-10-07protein level
1 84 32
2012-08-24protein level
1 65 32
2012-07-28protein level
1 63 32
2012-06-08protein level
1 66 32
2012-05-07protein level
1 68 32
2012-04-10protein level
1 68 32
2012-01-13protein level
1 35 32
2011-12-20protein level
1 35 32
2011-11-11protein level
1 35 30
2011-08-23protein level
1 35 30
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9HBL0-1
63 16 2 185585.7712
NX_Q9HBL0-2
4 16 0 47209.2884
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3389814,EBI-1039152 MET  
  .positive regulation of endothelial cell chemotaxis
.negative regulation of hydrogen peroxide-mediated programmed cell death
.semaphorin-plexin signaling pathway
  + 22 more...
.protein phosphatase binding
.ATP binding
.hepatocyte growth factor-activated receptor activity
.protein tyrosine kinase activity
.integral component of membrane
.cell surface
.basal plasma membrane
  + 3 more...
2 EBI-3389814,EBI-608057 AR  
  .negative regulation of extrinsic apoptotic signaling pathway
.regulation of establishment of protein localization to plasma membrane
.protein oligomerization
  + 21 more...
.ATPase binding
.protein dimerization activity
.transcription regulatory region DNA binding
  + 14 more...
.protein complex
.cytosol
.cytoplasm
  + 3 more...
3 EBI-3389814,EBI-1379503 KIT  
  .melanocyte adhesion
.melanocyte migration
.cellular response to thyroid hormone stimulus
  + 69 more...
.metal ion binding
.protein homodimerization activity
.cytokine binding
  + 5 more...
.mast cell granule
.integral component of membrane
.cytoplasmic side of plasma membrane
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue388
bladder33
blood8
bone209
brain37
connective tissue73
embryonic tissue23
esophagus49
eye114
heart111
intestine146
kidney42
larynx85
liver24
lung128
mammary gland125
mouth60
muscle141
nerve128
ovary108
pancreas28
placenta88
prostate121
skin94
spleen131
stomach83
testis39
thymus62
thyroid214
trachea57
umbilical cord72
uterus90
vascular38
Health State
TissuesTPM*
normal77
breast (mammary gland) tumor64
chondrosarcoma120
colorectal tumor186
gastrointestinal tumor33
germ cell tumor11
glioma74
head and neck tumor74
kidney tumor72
leukemia10
lung tumor48
non-neoplasia113
ovarian tumor131
pancreatic tumor47
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor119
soft tissue/muscle tissue tumor15
uterine tumor55
Developmental Stage
TissuesTPM*
adult118
embryoid body42
neonate32
fetus80
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue194.9
adrenal gland62.3
appendix43.3
bone marrow30.4
cerebral cortex16.7
colon51.6
duodenum19.8
esophagus107.9
gallbladder90.7
heart muscle132.3
kidney85.6
liver21.3
lung119.4
lymph node11.9
ovary130.6
pancreas30.1
placenta57.7
prostate100
salivary gland42.6
skin16.3
small intestine21.7
spleen70.3
stomach16.1
testis31.4
thyroid gland55.6
urinary bladder102.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600076, gene) Tensin 1; TNS1OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2020 (C) Yonsei Proteome Research Center