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> Protein (NX_Q9HBM1)
Protein (NX_Q9HBM1)
Protein
Gene SymbolSPC25 to neXtProt (NX_Q9HBM1)
DescriptionKinetochore protein Spc25
Chromosome2
Location2q24.3 (169690642 ~ 169769881) to Ensembl
Sequene Features : Isoforms 1, Variants 26, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.small GTPase mediated signal transduction
.mitotic nuclear division
  + 3 more...
.N/A .Ndc80 complex
.cytosol
.nucleus
.condensed chromosome kinetochore
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 26 2
2014-09-19protein level
1 16 2
2014-05-27protein level
1 16 2
2014-02-25protein level
1 16 2
2013-12-09protein level
1 14 2
2013-11-01protein level
1 14 1
2013-09-12protein level
1 14 1
2013-08-17protein level
1 14 1
2013-07-15protein level
1 11 1
2013-06-11protein level
1 11 1
2013-02-12protein level
1 4 2
2012-12-20protein level
1 4 2
2012-10-30protein level
1 4 2
2012-10-07protein level
1 4 2
2012-08-24protein level
1 2 2
2012-07-28protein level
1 2 2
2012-06-08protein level
1 2 2
2012-05-07protein level
1 2 2
2012-04-10protein level
1 2 2
2012-01-13protein level
1 1 2
2011-12-20protein level
1 1 2
2011-11-11protein level
1 1 1
2011-08-23protein level
1 1 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9HBM1-1
11 0 0 26136.4466
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-999909,EBI-715849 NDC80  
  .attachment of mitotic spindle microtubules to kinetochore
.cell division
.attachment of spindle microtubules to kinetochore
  + 7 more...
.identical protein binding
.structural constituent of cytoskeleton
.Ndc80 complex
.membrane
.cytosol
  + 5 more...
2 EBI-999909,EBI-999900 SPC24  
  .cell division
.small GTPase mediated signal transduction
.mitotic nuclear division
.mitotic cell cycle
.N/A .Ndc80 complex
.cytosol
.nucleolus
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
bladder33
blood32
bone27
bone marrow41
brain11
embryonic tissue23
eye4
intestine4
kidney4
liver4
lung5
lymph45
lymph node66
mammary gland13
ovary9
pancreas28
pharynx24
placenta3
prostate5
skin14
testis4
Health State
TissuesTPM*
normal12
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor21
chondrosarcoma24
germ cell tumor34
glioma111
kidney tumor14
leukemia42
liver tumor10
lung tumor19
lymphoma41
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS31
prostate cancer9
skin tumor23
Developmental Stage
TissuesTPM*
adult5
embryoid body28
blastocyst16
fetus25
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland1.8
appendix6.6
bone marrow7.8
cerebral cortex2.9
colon5.5
duodenum4.6
esophagus3.5
lymph node11.9
pancreas1
placenta4
skin2.6
small intestine3.9
spleen1.5
stomach3
testis4.3
urinary bladder1.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609395, gene) Spindle pole body component 25, s. cerevisiae, homolog of; SPBC25OMIM


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