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> Protein (NX_Q9HD42)
Protein (NX_Q9HD42)
Protein
Gene SymbolCHMP1A to neXtProt (NX_Q9HD42)
DescriptionCharged multivesicular body protein 1a
Chromosome16
Location16q24.3 (89710839 ~ 89724253) to Ensembl
Sequene Features : Isoforms 2, Variants 16, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of mitotic spindle assembly
.cell division
.negative regulation of transcription, DNA-templated
  + 12 more...
.protein homodimerization activity
.protein domain specific binding
.zinc ion binding
.metallopeptidase activity
.extracellular exosome
.nuclear matrix
.endomembrane system
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 16 3
2014-09-19protein level
2 13 3
2014-05-27protein level
2 13 3
2014-02-25protein level
2 12 3
2013-12-09protein level
2 5 3
2013-11-01protein level
2 5 1
2013-09-12protein level
2 5 1
2013-08-17protein level
2 5 1
2013-07-15protein level
2 1 0
2013-06-11protein level
2 1 0
2013-02-12protein level
2 1 1
2012-12-20protein level
2 1 1
2012-10-30protein level
2 2 1
2012-10-07protein level
2 2 1
2012-08-24protein level
2 2 1
2012-07-28protein level
2 2 1
2012-06-08protein level
2 5 1
2012-05-07protein level
2 5 1
2012-04-10protein level
2 5 1
2012-01-13protein level
2 5 1
2011-12-20protein level
2 5 1
2011-11-11protein level
2 5 1
2011-08-23protein level
2 5 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9HD42-1
6 1 0 21689.1228
NX_Q9HD42-2
1 1 0 7358.5619
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1057156,EBI-396676 STAMBP  
  .negative regulation of Ras protein signal transduction
.negative regulation of neuron apoptotic process
.protein deubiquitination
  + 4 more...
.metal ion binding
.protein domain specific binding
.metallopeptidase activity
.ubiquitin-specific protease activity
.extracellular exosome
.cleavage furrow
.plasma membrane
  + 4 more...
2 EBI-1057156,EBI-1050865 USP8  
  .protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.regulation of proteasomal protein catabolic process
  + 6 more...
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.extrinsic component of endosome membrane
.midbody
.extrinsic component of plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland60
ascites50
blood147
bone41
bone marrow143
brain75
cervix288
connective tissue26
embryonic tissue75
eye114
heart22
intestine129
kidney37
larynx85
liver48
lung80
lymph248
lymph node33
mammary gland46
mouth45
muscle28
nerve64
ovary68
pancreas56
parathyroid48
pharynx98
placenta130
prostate47
salivary gland49
skin80
spleen37
stomach167
testis179
thymus12
tonsil117
trachea19
uterus81
Health State
TissuesTPM*
normal58
adrenal tumor158
breast (mammary gland) tumor75
cervical tumor86
chondrosarcoma48
colorectal tumor177
gastrointestinal tumor126
germ cell tumor34
glioma149
head and neck tumor67
kidney tumor87
leukemia105
liver tumor72
lung tumor77
lymphoma290
non-neoplasia72
ovarian tumor13
pancreatic tumor104
primitive neuroectodermal tumor of the CNS244
prostate cancer48
retinoblastoma107
skin tumor103
soft tissue/muscle tissue tumor95
uterine tumor88
Developmental Stage
TissuesTPM*
adult81
embryoid body42
blastocyst113
fetus46
infant85
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue27.7
adrenal gland23.8
appendix30.8
bone marrow36.1
cerebral cortex30.1
colon40.7
duodenum40.3
esophagus41.1
gallbladder34.5
heart muscle22.5
kidney30.7
liver13.8
lung33.8
lymph node34.5
ovary25.8
pancreas14
placenta30.9
prostate33.9
salivary gland25.1
skin41
small intestine44.4
spleen39.6
stomach46.8
testis42.6
thyroid gland31.1
urinary bladder30.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*164010, gene) Chmp family, member 1a; CHMP1AOMIM


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