Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9NQ50)
Protein (NX_Q9NQ50)
Protein
Gene SymbolMRPL40 to neXtProt (NX_Q9NQ50)
Description39S ribosomal protein L40, mitochondrial
Chromosome22
Location22q11.21 (19419425 ~ 19423598) to Ensembl
Sequene Features : Isoforms 1, Variants 32, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mitochondrial translational termination
.mitochondrial translational elongation
.mitochondrial translational initiation
  + 3 more...
.poly(A) RNA binding .mitochondrial ribosome
.mitochondrial inner membrane
.mitochondrion
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 32 1
2014-09-19protein level
1 25 1
2014-05-27protein level
1 25 1
2014-02-25protein level
1 25 1
2013-12-09protein level
1 18 1
2013-11-01protein level
1 18 0
2013-09-12protein level
1 18 0
2013-08-17protein level
1 18 0
2013-07-15protein level
1 13 0
2013-06-11protein level
1 13 0
2013-02-12protein level
1 10 0
2012-12-20protein level
1 10 0
2012-10-30protein level
1 10 0
2012-10-07protein level
1 10 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 10 0
2012-05-07protein level
1 9 0
2012-04-10protein level
1 9 0
2012-01-13protein level
1 5 0
2011-12-20protein level
1 5 0
2011-11-11protein level
1 5 0
2011-08-23protein level
1 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NQ50-1
8 0 0 24475.1166
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1053902,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-1053902,EBI-717422 TFCP2  
  .regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.sequence-specific DNA binding
.protein C-terminus binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
3 EBI-1053902,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
4 EBI-1053902,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
blood73
bone41
brain29
cervix20
connective tissue13
embryonic tissue14
eye52
heart78
intestine43
kidney47
liver4
lung65
lymph22
lymph node33
mammary gland19
mouth90
muscle84
ovary29
pancreas89
parathyroid145
pharynx24
placenta14
prostate26
salivary gland148
skin52
stomach10
testis11
thyroid42
umbilical cord145
uterus56
vascular58
Health State
TissuesTPM*
normal38
breast (mammary gland) tumor10
chondrosarcoma36
colorectal tumor26
gastrointestinal tumor16
germ cell tumor11
glioma55
head and neck tumor29
kidney tumor29
leukemia31
lung tumor19
lymphoma13
non-neoplasia20
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS70
prostate cancer28
retinoblastoma21
skin tumor79
soft tissue/muscle tissue tumor31
uterine tumor44
Developmental Stage
TissuesTPM*
adult31
embryoid body28
neonate64
fetus64
infant85
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.3
adrenal gland30.8
appendix16.4
bone marrow12.8
cerebral cortex13.3
colon18
duodenum12.7
esophagus15.2
gallbladder16.9
heart muscle39.7
kidney27.4
liver29.9
lung15
lymph node19.3
ovary23.9
pancreas13.6
placenta15
prostate24.5
salivary gland28.7
skin15.3
small intestine12.8
spleen15.9
stomach15.9
testis21.2
thyroid gland40.9
urinary bladder21
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowLow
breastLow
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisMedium
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyMedium
lateral ventricleMedium
liverHigh
lungHigh
lymph nodeHigh
nasopharynxMedium
oral mucosaLow
pancreasMedium
parathyroid glandHigh
placentaMedium
prostateLow
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleMedium
skin 1Medium
skin 2Low
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Low
spleenLow
stomach 1High
stomach 2High
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605089, gene) Mitochondrial ribosomal protein l40; MRPL40OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center