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> Protein (NX_Q9NQC1)
Protein (NX_Q9NQC1)
Protein
Gene SymbolJADE2 to neXtProt (NX_Q9NQC1)
DescriptionProtein Jade-2
Chromosome5
Location5q31.1 (133860003 ~ 133918918) to Ensembl
Sequene Features : Isoforms 3, Variants 31, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.SMAD protein signal transduction
.histone H4-K12 acetylation
.histone H4-K8 acetylation
  + 2 more...
.zinc ion binding .extracellular exosome
.nucleoplasm
.histone acetyltransferase complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 31 4
2014-09-19protein level
3 67 4
2014-05-27protein level
3 67 4
2014-02-25protein level
3 67 4
2013-12-09protein level
3 48 4
2013-11-01protein level
3 47 4
2013-09-12protein level
3 47 4
2013-08-17protein level
3 47 4
2013-07-15protein level
3 31 4
2013-06-11protein level
3 31 4
2013-02-12protein level
3 15 12
2012-12-20protein level
3 15 12
2012-10-30protein level
3 24 12
2012-10-07protein level
3 24 4
2012-08-24protein level
3 24 4
2012-07-28protein level
3 24 4
2012-06-08protein level
3 2 4
2012-05-07protein level
3 2 4
2012-04-10protein level
3 2 4
2012-01-13protein level
3 2 4
2011-12-20protein level
3 9 4
2011-11-11protein level
3 9 4
2011-08-23protein level
3 9 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NQC1-1
1 34 3 87409.8607
NX_Q9NQC1-2
1 34 3 87352.8394
NX_Q9NQC1-3
1 25 3 63425.1118
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2796167,EBI-488533 ING5  
  .positive regulation of apoptotic signaling pathway
.negative regulation of growth
.positive regulation of transcription, DNA-templated
  + 7 more...
.methylated histone binding
.zinc ion binding
.chromatin binding
.MOZ/MORF histone acetyltransferase complex
.nucleoplasm
.nucleus
2 EBI-10311936,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
bladder33
blood40
bone97
brain19
cervix20
connective tissue46
embryonic tissue14
eye33
intestine68
kidney18
larynx894
liver24
lung20
lymph90
lymph node167
mammary gland6
mouth60
muscle9
nerve64
ovary49
pancreas51
parathyroid97
pharynx24
pituitary gland60
placenta10
prostate31
salivary gland49
skin75
spleen18
stomach73
testis13
thymus112
thyroid42
trachea38
uterus43
vascular19
Health State
TissuesTPM*
normal23
chondrosarcoma120
colorectal tumor97
gastrointestinal tumor59
germ cell tumor37
glioma65
head and neck tumor194
kidney tumor14
leukemia52
liver tumor10
lung tumor19
lymphoma69
non-neoplasia20
ovarian tumor52
pancreatic tumor57
primitive neuroectodermal tumor of the CNS15
prostate cancer28
skin tumor119
soft tissue/muscle tissue tumor31
uterine tumor22
Developmental Stage
TissuesTPM*
adult49
embryoid body28
neonate64
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.8
adrenal gland17.5
appendix16.7
bone marrow6.6
cerebral cortex11.5
colon11
duodenum10.7
esophagus10.6
gallbladder13.1
heart muscle11.2
kidney17.6
liver1.9
lung14.8
lymph node26.4
ovary24.8
pancreas6.3
placenta8
prostate9.9
salivary gland11.7
skin8.3
small intestine14.6
spleen27.6
stomach13.3
testis11.1
thyroid gland21.6
urinary bladder16.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610515, gene) Phd finger protein 15; PHF15OMIM


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