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> Protein (NX_Q9NQZ2)
Protein (NX_Q9NQZ2)
Protein
Gene SymbolUTP3 to neXtProt (NX_Q9NQZ2)
DescriptionSomething about silencing protein 10
Chromosome4
Location4q13.3 (71554196 ~ 71556267) to Ensembl
Sequene Features : Isoforms 1, Variants 57, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.chromatin modification
.brain development
.maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
.poly(A) RNA binding .small-subunit processome
.nucleolus
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 57 8
2014-09-19protein level
1 47 8
2014-05-27protein level
1 47 8
2014-02-25protein level
1 48 6
2013-12-09protein level
1 38 6
2013-11-01protein level
1 37 6
2013-09-12protein level
1 37 6
2013-08-17protein level
1 37 6
2013-07-15protein level
1 27 5
2013-06-11protein level
1 27 5
2013-02-12protein level
1 14 7
2012-12-20protein level
1 13 7
2012-10-30protein level
1 17 7
2012-10-07protein level
1 17 7
2012-08-24protein level
1 15 7
2012-07-28protein level
1 14 7
2012-06-08protein level
1 16 7
2012-05-07protein level
1 14 7
2012-04-10protein level
1 14 7
2012-01-13protein level
1 6 7
2011-12-20protein level
1 6 7
2011-11-11protein level
1 6 7
2011-08-23protein level
1 6 7
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NQZ2-1
14 0 0 54524.9372
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-714067,EBI-739789 DVL3  
  .positive regulation of canonical Wnt signaling pathway
.planar cell polarity pathway involved in neural tube closure
.cochlea morphogenesis
  + 12 more...
.protein heterodimerization activity
.beta-catenin binding
.frizzled binding
  + 2 more...
.cytosol
2 EBI-714067,EBI-5278764 CDCA7L  
  .positive regulation of cell proliferation
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .cytoplasm
.nucleolus
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites50
bladder33
blood8
bone55
bone marrow61
brain21
cervix20
connective tissue40
embryonic tissue65
esophagus99
eye47
heart67
intestine38
kidney37
liver48
lung68
lymph22
lymph node33
mammary gland33
mouth15
muscle18
ovary29
pancreas14
placenta35
prostate15
salivary gland49
skin14
spleen74
stomach83
testis6
thyroid64
uterus17
Health State
TissuesTPM*
normal28
adrenal tumor79
breast (mammary gland) tumor53
cervical tumor28
chondrosarcoma72
colorectal tumor26
esophageal tumor115
gastrointestinal tumor50
germ cell tumor37
glioma9
head and neck tumor22
kidney tumor29
leukemia21
liver tumor83
lung tumor9
lymphoma13
non-neoplasia72
ovarian tumor39
pancreatic tumor19
primitive neuroectodermal tumor of the CNS23
prostate cancer19
retinoblastoma21
skin tumor23
soft tissue/muscle tissue tumor31
Developmental Stage
TissuesTPM*
adult40
embryoid body100
blastocyst48
fetus32
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.8
adrenal gland22.5
appendix25.1
bone marrow11.6
cerebral cortex15.9
colon16.6
duodenum13.7
esophagus16
gallbladder15.7
heart muscle13
kidney20.7
liver15.1
lung17.4
lymph node30
ovary14.6
pancreas5.8
placenta14.8
prostate13.5
salivary gland11.4
skin14.8
small intestine14.2
spleen27.6
stomach16.1
testis12.7
thyroid gland16.5
urinary bladder17.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611614, gene) Utp3, s. cerevisiae, homolog of; UTP3OMIM


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