Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9NQZ6)
Protein (NX_Q9NQZ6)
Protein
Gene SymbolZC4H2 to neXtProt (NX_Q9NQZ6)
DescriptionZinc finger C4H2 domain-containing protein
ChromosomeX
LocationXq11.2 (64136250 ~ 64254593) to Ensembl
Sequene Features : Isoforms 5, Variants 55, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.spinal cord motor neuron differentiation
.neuromuscular junction development
.nervous system development
.metal ion binding .postsynaptic membrane
.cell junction
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 55 0
2014-09-19protein level
5 42 0
2014-05-27protein level
5 40 0
2014-02-25protein level
5 39 0
2013-12-09protein level
5 35 0
2013-11-01protein level
5 33 0
2013-09-12protein level
5 33 0
2013-08-17protein level
5 33 0
2013-07-15transcript level
4 22 0
2013-06-11transcript level
4 22 0
2013-02-12transcript level
4 6 0
2012-12-20transcript level
4 6 0
2012-10-30transcript level
4 7 0
2012-10-07transcript level
4 7 0
2012-08-24transcript level
4 3 0
2012-07-28transcript level
4 3 0
2012-06-08transcript level
4 5 0
2012-05-07transcript level
4 5 0
2012-04-10transcript level
4 5 0
2012-01-13transcript level
3 2 0
2011-12-20transcript level
3 2 0
2011-11-11transcript level
3 2 0
2011-08-23protein level
3 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NQZ6-1
0 12 0 26227.3761
NX_Q9NQZ6-2
0 8 0 15876.0949
NX_Q9NQZ6-3
0 11 0 23496.0132
NX_Q9NQZ6-4
2 8 0 20629.4826
NX_Q9NQZ6-5
1 11 0 25721.2363
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-747993,EBI-741237 SORBS3  
  .positive regulation of stress fiber assembly
.positive regulation of cytoskeleton organization
.positive regulation of MAPK cascade
  + 5 more...
.vinculin binding
.structural constituent of cytoskeleton
.focal adhesion
.cytoskeleton
.cytosol
.nucleus
2 EBI-747993,EBI-10177272 ZNF250  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
3 EBI-747993,EBI-10283126 ZNF524  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
4 EBI-747993,EBI-10322867 ZNF223  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
5 EBI-747993,EBI-1105370 ZNF490  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
blood40
bone27
brain72
cervix20
connective tissue20
embryonic tissue28
eye14
heart78
intestine17
kidney37
liver9
lung11
lymph135
lymph node11
mammary gland52
muscle37
ovary9
pancreas9
parathyroid48
prostate15
skin9
spleen18
stomach10
testis85
thymus276
uterus56
vascular38
Health State
TissuesTPM*
normal38
adrenal tumor79
breast (mammary gland) tumor21
chondrosarcoma24
gastrointestinal tumor8
germ cell tumor292
glioma83
kidney tumor72
leukemia31
liver tumor20
lung tumor9
lymphoma138
non-neoplasia20
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS125
prostate cancer19
soft tissue/muscle tissue tumor23
uterine tumor22
Developmental Stage
TissuesTPM*
adult52
embryoid body14
blastocyst32
neonate32
fetus86
infant127
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.8
adrenal gland7
appendix4.8
bone marrow2.7
cerebral cortex10.9
colon6.3
duodenum5
esophagus3.8
gallbladder6.8
heart muscle6.3
kidney7.7
liver3.9
lung5.2
lymph node4.6
ovary11.5
pancreas3
prostate7.2
salivary gland4.3
skin2.3
small intestine5.6
spleen3.9
stomach7.2
testis2.5
thyroid gland8.4
urinary bladder6.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(%314580, phenotype) Wieacker syndromeOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2020 (C) Yonsei Proteome Research Center