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> Protein (NX_Q9NR56)
Protein (NX_Q9NR56)
Protein
Gene SymbolMBNL1 to neXtProt (NX_Q9NR56)
DescriptionMuscleblind-like protein 1
Chromosome3
Location3q25.1 (151961617 ~ 152183569) to Ensembl
Sequene Features : Isoforms 7, Variants 59, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.myoblast differentiation
.regulation of RNA splicing
.embryonic limb morphogenesis
  + 7 more...
.metal ion binding
.poly(A) RNA binding
.double-stranded RNA binding
.RNA binding
.cytoplasmic stress granule
.centrosome
.cytoplasm
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
7 59 3
2014-09-19protein level
7 42 3
2014-05-27protein level
7 40 3
2014-02-25protein level
7 40 3
2013-12-09protein level
7 28 3
2013-11-01protein level
7 27 3
2013-09-12protein level
7 27 3
2013-08-17protein level
7 27 3
2013-07-15protein level
7 19 1
2013-06-11protein level
7 19 1
2013-02-12protein level
7 4 0
2012-12-20protein level
6 4 0
2012-10-30protein level
6 8 0
2012-10-07protein level
6 8 0
2012-08-24protein level
6 7 0
2012-07-28protein level
6 7 0
2012-06-08protein level
6 9 0
2012-05-07protein level
3 4 0
2012-04-10protein level
3 4 0
2012-01-13protein level
3 1 0
2011-12-20protein level
3 1 0
2011-11-11protein level
3 1 0
2011-08-23protein level
3 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NR56-1
2 5 6 41789.8713
NX_Q9NR56-2
0 6 6 39804.7826
NX_Q9NR56-3
0 6 6 33028.2483
NX_Q9NR56-4
0 6 6 34188.8021
NX_Q9NR56-5
0 6 6 40965.3364
NX_Q9NR56-6
1 5 6 37049.2667
NX_Q9NR56-7
3 4 6 36967.2367
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2805004,EBI-7875264 DAB1  
  .lateral motor column neuron migration
.Golgi localization
.negative regulation of axonogenesis
  + 15 more...
.N/A .perinuclear region of cytoplasm
.apical part of cell
.neuronal cell body
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland121
ascites50
bladder435
blood204
bone83
bone marrow328
brain41
cervix61
connective tissue134
ear124
embryonic tissue23
esophagus99
eye52
heart134
intestine112
kidney156
larynx170
liver121
lung62
lymph22
lymph node479
mammary gland105
mouth136
muscle300
nerve386
ovary78
pancreas84
pharynx24
placenta49
prostate158
salivary gland444
skin170
spleen18
stomach94
testis45
thymus138
thyroid107
trachea77
umbilical cord217
uterus280
vascular542
Health State
TissuesTPM*
normal120
adrenal tumor158
bladder carcinoma454
breast (mammary gland) tumor53
cervical tumor86
chondrosarcoma132
colorectal tumor88
esophageal tumor115
gastrointestinal tumor84
germ cell tumor163
glioma46
head and neck tumor127
kidney tumor217
leukemia148
liver tumor31
lymphoma96
non-neoplasia93
ovarian tumor78
pancreatic tumor85
primitive neuroectodermal tumor of the CNS62
prostate cancer144
skin tumor95
soft tissue/muscle tissue tumor127
uterine tumor166
Developmental Stage
TissuesTPM*
adult96
embryoid body57
neonate193
fetus91
infant42
juvenile197
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue106.6
adrenal gland40.8
appendix111.7
bone marrow156.7
cerebral cortex27.5
colon71.3
duodenum45
esophagus92.3
gallbladder114.1
heart muscle66.4
kidney33.7
liver31.5
lung77.1
lymph node162.8
ovary57.5
pancreas14.7
placenta31.9
prostate54.8
salivary gland30.1
skin57.4
small intestine57.8
spleen84.5
stomach42.3
testis22.6
thyroid gland49.5
urinary bladder117.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#160900, phenotype) Myotonic dystrophy 1; DM1OMIM
2(*606516, gene) Muscleblind-like protein 1; MBNL1OMIM


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