Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9NRS4)
Protein (NX_Q9NRS4)
Protein
Gene SymbolTMPRSS4 to neXtProt (NX_Q9NRS4)
DescriptionTransmembrane protease serine 4
Chromosome11
Location11q23.3 (117947753 ~ 117992605) to Ensembl
Sequene Features : Isoforms 4, Variants 65, PTMs 10 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.proteolysis .scavenger receptor activity
.serine-type endopeptidase activity
.integral component of membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 65 10
2014-09-19protein level
4 55 10
2014-05-27protein level
4 54 10
2014-02-25protein level
3 53 10
2013-12-09protein level
3 35 10
2013-11-01protein level
3 29 10
2013-09-12protein level
3 29 10
2013-08-17protein level
3 29 10
2013-07-15transcript level
3 26 10
2013-06-11transcript level
3 26 10
2013-02-12transcript level
3 18 28
2012-12-20transcript level
3 20 28
2012-10-30transcript level
3 23 28
2012-10-07transcript level
3 23 10
2012-08-24transcript level
3 21 10
2012-07-28transcript level
3 21 10
2012-06-08transcript level
3 22 10
2012-05-07transcript level
3 18 10
2012-04-10transcript level
3 18 10
2012-01-13transcript level
3 8 10
2011-12-20transcript level
3 8 10
2011-11-11transcript level
3 8 10
2011-08-23transcript level
3 8 10
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NRS4-1
0 20 0 48214.9772
NX_Q9NRS4-2
0 19 0 47654.6829
NX_Q9NRS4-3
1 19 0 47973.8353
NX_Q9NRS4-4
1 18 0 43757.2127
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10312990,EBI-7131783 SYNE4  
  .establishment of epithelial cell apical/basal polarity .N/A .LINC complex
.integral component of nuclear outer membrane
2 EBI-10313040,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
3 EBI-10313040,EBI-8649725 TMEM79  
  .cornification
.establishment of skin barrier
.positive regulation of epidermis development
  + 4 more...
.N/A .trans-Golgi network membrane
.integral component of membrane
.lysosomal membrane
4 EBI-10312990,EBI-3939278 CLEC7A  
  .innate immune response
.defense response to protozoan
.T cell activation
  + 6 more...
.metal ion binding
.MHC protein binding
.carbohydrate binding
.signaling pattern recognition receptor activity
.integral component of membrane
.plasma membrane
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites200
bladder167
blood8
brain2
cervix41
embryonic tissue9
esophagus942
eye28
intestine301
kidney66
larynx127
liver38
lung50
mammary gland46
mouth725
muscle9
ovary68
pancreas93
pharynx24
placenta7
prostate31
stomach177
thymus25
trachea270
uterus47
Health State
TissuesTPM*
normal19
breast (mammary gland) tumor75
cervical tumor57
colorectal tumor275
esophageal tumor1101
gastrointestinal tumor177
germ cell tumor3
head and neck tumor388
kidney tumor14
leukemia31
lung tumor9
non-neoplasia41
ovarian tumor91
pancreatic tumor190
prostate cancer9
uterine tumor99
Developmental Stage
TissuesTPM*
adult46
embryoid body14
fetus17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix10.4
colon80.4
duodenum59.4
esophagus85
gallbladder35.4
heart muscle1.2
kidney14
lung1.3
prostate2.1
skin7.2
small intestine40.3
stomach47.7
testis2.7
urinary bladder87.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606565, gene) Transmembrane protease, serine 4; TMPRSS4OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center