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> Protein (NX_Q9NRW3)
Protein (NX_Q9NRW3)
Protein
Gene SymbolAPOBEC3C to neXtProt (NX_Q9NRW3)
DescriptionDNA dC->dU-editing enzyme APOBEC-3C
Chromosome22
Location22q13.1 (39410088 ~ 39416357) to Ensembl
Sequene Features : Isoforms 1, Variants 35, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.DNA demethylation
.defense response to virus
.innate immune response
  + 4 more...
.poly(A) RNA binding
.hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
.zinc ion binding
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 35 2
2014-09-19protein level
1 32 2
2014-05-27protein level
1 32 2
2014-02-25protein level
1 31 2
2013-12-09protein level
1 17 2
2013-11-01protein level
1 16 0
2013-09-12protein level
1 16 0
2013-08-17protein level
1 16 0
2013-07-15protein level
1 10 0
2013-06-11protein level
1 10 0
2013-02-12protein level
1 5 0
2012-12-20protein level
1 5 0
2012-10-30protein level
1 6 0
2012-10-07protein level
1 6 0
2012-08-24protein level
1 5 0
2012-07-28protein level
1 5 0
2012-06-08protein level
1 7 0
2012-05-07protein level
1 4 0
2012-04-10protein level
1 4 0
2012-01-13protein level
1 6 0
2011-12-20protein level
1 6 0
2011-11-11protein level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NRW3-1
9 0 1 22810.9005
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1044593,EBI-8638511 RBMY1A1  
  .RNA splicing
.mRNA processing
.regulation of alternative mRNA splicing, via spliceosome
.mRNA binding
.nucleotide binding
.nucleus
2 EBI-1044593,EBI-743526 RBMX  
  .cellular response to interleukin-1
.protein homooligomerization
.positive regulation of mRNA splicing, via spliceosome
  + 10 more...
.poly(A) RNA binding
.mRNA binding
.single-stranded RNA binding
  + 4 more...
.catalytic step 2 spliceosome
.extracellular exosome
.supraspliceosomal complex
  + 6 more...
3 EBI-1044593,EBI-8642021 RBMY1F  
  .RNA splicing
.spermatogenesis
.mRNA processing
.RNA binding
.nucleotide binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland212
ascites200
bladder33
blood81
bone55
bone marrow164
brain12
connective tissue13
embryonic tissue32
esophagus99
eye19
heart22
intestine34
kidney14
larynx213
liver38
lung32
lymph203
lymph node66
mammary gland33
muscle18
ovary19
pancreas32
pharynx98
placenta21
prostate21
salivary gland98
skin61
spleen112
testis66
thymus12
tonsil176
trachea57
uterus77
vascular58
Health State
TissuesTPM*
normal30
adrenal tumor395
breast (mammary gland) tumor42
colorectal tumor62
esophageal tumor115
gastrointestinal tumor67
germ cell tumor11
glioma74
head and neck tumor52
kidney tumor29
leukemia21
liver tumor83
lung tumor38
lymphoma138
non-neoplasia31
pancreatic tumor9
primitive neuroectodermal tumor of the CNS39
skin tumor79
soft tissue/muscle tissue tumor127
Developmental Stage
TissuesTPM*
adult39
embryoid body57
blastocyst32
neonate32
fetus10
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10
adrenal gland28.8
appendix29.5
bone marrow18.9
cerebral cortex2.9
colon22.2
duodenum12.3
esophagus21.9
gallbladder21
heart muscle18
kidney4
liver3.4
lung19.1
lymph node53.3
ovary37.6
pancreas3
placenta10.2
prostate22.8
salivary gland16.7
skin16.8
small intestine10.9
spleen36.1
stomach17.4
testis34.2
thyroid gland15.8
urinary bladder40.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607750, gene) Apolipoprotein b mrna-editing enzyme, catalytic polypeptide-like 3c;OMIM


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