Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9NT62)
Protein (NX_Q9NT62)
Protein
Gene SymbolATG3 to neXtProt (NX_Q9NT62)
DescriptionUbiquitin-like-conjugating enzyme ATG3
Chromosome3
Location3q13.2 (112251356 ~ 112280893) to Ensembl
Sequene Features : Isoforms 2, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of cilium assembly
.nucleophagy
.mitochondrial fragmentation involved in apoptotic process
  + 5 more...
.enzyme binding
.ubiquitin-like protein transferase activity
.Atg12 transferase activity
  + 2 more...
.cytosol
.cytoplasmic ubiquitin ligase complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 28 3
2014-09-19protein level
2 24 3
2014-05-27protein level
2 24 3
2014-02-25protein level
2 24 3
2013-12-09protein level
2 19 3
2013-11-01protein level
2 19 3
2013-09-12protein level
2 19 3
2013-08-17protein level
2 19 3
2013-07-15protein level
2 12 1
2013-06-11protein level
2 12 1
2013-02-12protein level
2 6 6
2012-12-20protein level
2 6 6
2012-10-30protein level
2 7 6
2012-10-07protein level
2 7 3
2012-08-24protein level
2 3 3
2012-07-28protein level
2 3 3
2012-06-08protein level
2 4 3
2012-05-07protein level
2 4 3
2012-04-10protein level
2 4 3
2012-01-13protein level
2 9 3
2011-12-20protein level
2 9 3
2011-11-11protein level
2 9 3
2011-08-23protein level
2 9 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NT62-1
2 10 0 35841.3529
NX_Q9NT62-2
2 10 0 35444.3067
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-988094,EBI-712001 GABARAP  
  .membrane fusion
.nucleophagy
.extrinsic apoptotic signaling pathway via death domain receptors
  + 5 more...
.GABA receptor binding
.beta-tubulin binding
.microtubule binding
.perinuclear region of cytoplasm
.cell body
.cytoplasmic vesicle
  + 13 more...
2 EBI-988094,EBI-720116 GABARAPL2  
  .negative regulation of proteasomal protein catabolic process
.membrane fusion
.nucleophagy
  + 7 more...
.ATPase binding
.GABA receptor binding
.beta-tubulin binding
  + 2 more...
.cytoplasmic vesicle
.extrinsic component of membrane
.cytosol
  + 7 more...
3 EBI-988094,EBI-2946676 TECPR1  
  .autophagy
.autophagic vacuole fusion
.phosphatidylinositol-3-phosphate binding .cytoplasmic vesicle
.integral component of membrane
.lysosomal membrane
.autophagic vacuole membrane
4 EBI-988094,EBI-373144 MAP1LC3B  
  .regulation of mitochondrion degradation
.membrane fusion
.nucleophagy
  + 3 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 9 more...
5 EBI-988094,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites100
bladder234
blood73
bone111
bone marrow41
brain72
cervix41
connective tissue556
ear124
embryonic tissue61
esophagus49
eye52
heart44
intestine77
kidney71
liver58
lung68
lymph67
lymph node66
mammary gland105
mouth15
muscle56
ovary49
pancreas42
parathyroid48
pharynx73
pituitary gland60
placenta56
prostate31
salivary gland49
skin66
stomach94
testis80
thymus62
thyroid85
uterus103
vascular58
Health State
TissuesTPM*
normal60
adrenal tumor158
bladder carcinoma341
breast (mammary gland) tumor128
cervical tumor28
chondrosarcoma84
colorectal tumor97
gastrointestinal tumor67
germ cell tumor49
glioma37
head and neck tumor44
kidney tumor87
leukemia74
liver tumor83
lung tumor38
lymphoma69
non-neoplasia10
ovarian tumor52
pancreatic tumor38
primitive neuroectodermal tumor of the CNS31
prostate cancer48
retinoblastoma43
skin tumor103
soft tissue/muscle tissue tumor678
uterine tumor110
Developmental Stage
TissuesTPM*
adult117
embryoid body42
blastocyst81
fetus43
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue28.8
adrenal gland37.1
appendix49.7
bone marrow58
cerebral cortex25.6
colon38.4
duodenum33.5
esophagus42.6
gallbladder28.8
heart muscle30.9
kidney34.3
liver21.2
lung28.1
lymph node51.2
ovary26.3
pancreas22.8
placenta32.2
prostate22.1
salivary gland25
skin25.1
small intestine33.3
spleen42.3
stomach32.8
testis74.1
thyroid gland48.3
urinary bladder41.2
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowMedium
breastLow
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
esophagusLow
fallopian tubeLow
gallbladderMedium
heart muscleLow
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverMedium
lungLow
nasopharynxLow
oral mucosaLow
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateHigh
rectumHigh
salivary glandLow
seminal vesicleLow
skin 1Low
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilLow
urinary bladderLow
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609606, gene) Autophagy 3, s. cerevisiae, homolog of; ATG3OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center