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> Protein (NX_Q9NTW7)
Protein (NX_Q9NTW7)
Protein
Gene SymbolZFP64 to neXtProt (NX_Q9NTW7)
DescriptionZinc finger protein 64 homolog, isoforms 3 and 4
Chromosome20
Location20q13.2 (50668202 ~ 50820847) to Ensembl
Sequene Features : Isoforms 4, Variants 174, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 174 0
2014-09-19protein level
4 127 0
2014-05-27transcript level
4 127 0
2014-02-25transcript level
4 124 0
2013-12-09transcript level
4 105 0
2013-11-01transcript level
4 95 0
2013-09-12transcript level
4 95 0
2013-08-17protein level
4 95 0
2013-07-15protein level
3 34 1
2013-06-11protein level
3 34 1
2013-02-12protein level
3 16 2
2012-12-20protein level
3 16 2
2012-10-30protein level
3 19 2
2012-10-07protein level
3 19 2
2012-08-24transcript level
3 16 2
2012-07-28transcript level
3 16 2
2012-06-08transcript level
3 18 2
2012-05-07transcript level
3 18 2
2012-04-10transcript level
3 18 2
2012-01-13transcript level
3 12 2
2011-12-20transcript level
3 12 2
2011-11-11transcript level
3 12 0
2011-08-23transcript level
3 12 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NTW7-1
0 21 14 72169.8624
NX_Q9NTW7-2
2 20 2 48133.256
NX_Q9NTW7-3
1 10 14 46222.1673
NX_Q9NTW7-4
1 0 26 74415.4773
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-745730,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
2 EBI-745730,EBI-1048159 MFAP1  
  .extracellular matrix organization .poly(A) RNA binding .extracellular region
.microfibril
3 EBI-745730,EBI-358049 BYSL  
  .cell proliferation
.female pregnancy
.cell adhesion
  + 2 more...
.poly(A) RNA binding .apical part of cell
.intracellular membrane-bounded organelle
.membrane
  + 3 more...
4 EBI-745730,EBI-701903 FHL2  
  .heart trabecula formation
.ventricular cardiac muscle cell development
.atrial cardiac muscle cell development
  + 9 more...
.androgen receptor binding
.identical protein binding
.zinc ion binding
  + 2 more...
.M band
.Z disc
.actin cytoskeleton
  + 3 more...
5 EBI-745730,EBI-744506 FAM124A  
  .N/A .N/A .N/A
6 EBI-745730,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
7 EBI-745730,EBI-8637627 AEN  
  .nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation
.exonuclease activity
.nucleic acid binding
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus
8 EBI-745730,EBI-725997 TRIM41  
  .protein ubiquitination .ligase activity
.zinc ion binding
.cytoplasm
.nucleolus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
bladder33
blood8
brain37
cervix123
connective tissue33
embryonic tissue37
esophagus49
eye14
heart22
intestine34
kidney28
liver4
lung29
lymph180
mammary gland19
mouth166
muscle18
ovary78
pancreas14
parathyroid242
pharynx24
placenta42
prostate42
skin23
spleen56
stomach20
testis68
thymus37
thyroid21
uterus34
Health State
TissuesTPM*
normal27
breast (mammary gland) tumor21
cervical tumor28
chondrosarcoma48
colorectal tumor53
esophageal tumor57
gastrointestinal tumor16
germ cell tumor106
glioma46
head and neck tumor89
leukemia21
lung tumor29
lymphoma110
non-neoplasia51
ovarian tumor105
primitive neuroectodermal tumor of the CNS55
prostate cancer38
retinoblastoma21
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult36
embryoid body57
blastocyst32
fetus48
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.5
adrenal gland5.2
appendix5.6
bone marrow1.9
cerebral cortex5.5
colon7.1
duodenum7
esophagus6.3
gallbladder5.3
heart muscle4.4
kidney5.4
liver3.3
lung5.8
lymph node6
ovary8.9
pancreas2.6
placenta4.4
prostate6.9
salivary gland4.5
skin8.1
small intestine5
spleen6
stomach6.7
testis12.4
thyroid gland6.7
urinary bladder8.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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