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> Protein (NX_Q9NUK0)
Protein (NX_Q9NUK0)
Protein
Gene SymbolMBNL3 to neXtProt (NX_Q9NUK0)
DescriptionMuscleblind-like protein 3
ChromosomeX
LocationXq26.2 (131503345 ~ 131623996) to Ensembl
Sequene Features : Isoforms 5, Variants 40, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of myoblast differentiation
.regulation of RNA splicing
.RNA splicing
  + 2 more...
.metal ion binding
.poly(A) RNA binding
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 40 0
2014-09-19protein level
5 27 0
2014-05-27protein level
5 27 0
2014-02-25protein level
5 27 0
2013-12-09protein level
5 23 0
2013-11-01protein level
5 21 0
2013-09-12protein level
5 21 0
2013-08-17protein level
5 21 0
2013-07-15protein level
5 15 0
2013-06-11protein level
5 15 0
2013-02-12protein level
5 5 0
2012-12-20protein level
5 5 0
2012-10-30protein level
5 7 0
2012-10-07protein level
5 7 0
2012-08-24protein level
4 3 0
2012-07-28protein level
4 3 0
2012-06-08protein level
4 5 0
2012-05-07protein level
4 5 0
2012-04-10protein level
4 5 0
2012-01-13protein level
4 3 0
2011-12-20protein level
4 3 0
2011-11-11protein level
4 3 0
2011-08-23transcript level
4 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NUK0-1
0 8 3 38506.059
NX_Q9NUK0-2
1 6 3 36355.7738
NX_Q9NUK0-3
0 5 2 32920.3596
NX_Q9NUK0-4
1 4 2 31752.7848
NX_Q9NUK0-5
1 4 0 27668.6248
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6661142,EBI-7875264 DAB1  
  .lateral motor column neuron migration
.Golgi localization
.negative regulation of axonogenesis
  + 15 more...
.N/A .perinuclear region of cytoplasm
.apical part of cell
.neuronal cell body
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
blood24
brain3
connective tissue20
embryonic tissue9
eye9
heart11
intestine17
liver43
lung14
lymph node89
mammary gland33
mouth30
muscle18
pancreas42
pharynx24
pituitary gland121
placenta187
prostate21
skin23
stomach31
testis66
thymus12
Health State
TissuesTPM*
normal46
bladder carcinoma56
breast (mammary gland) tumor53
chondrosarcoma24
colorectal tumor26
gastrointestinal tumor8
germ cell tumor56
head and neck tumor22
liver tumor20
non-neoplasia10
pancreatic tumor28
primitive neuroectodermal tumor of the CNS15
retinoblastoma21
skin tumor23
uterine tumor77
Developmental Stage
TissuesTPM*
adult42
embryoid body14
blastocyst16
neonate64
fetus57
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.1
adrenal gland12
appendix9
bone marrow8.5
colon13.3
duodenum9.4
esophagus10.4
gallbladder6
heart muscle7.1
kidney8.2
liver27.2
lung4.5
lymph node12.4
ovary4.6
pancreas4.3
placenta158.6
prostate3.9
salivary gland4.8
skin10.2
small intestine8.5
spleen10.6
stomach12.2
testis52.4
thyroid gland8.1
urinary bladder11.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300413, gene) Muscleblind-like protein 3; MBNL3OMIM


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