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> Protein (NX_Q9NV56)
Protein (NX_Q9NV56)
Protein
Gene SymbolMRGBP to neXtProt (NX_Q9NV56)
DescriptionMRG/MORF4L-binding protein
Chromosome20
Location20q13.33 (61427805 ~ 61431945) to Ensembl
Sequene Features : Isoforms 1, Variants 2, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of growth
.chromatin modification
.regulation of transcription, DNA-templated
  + 2 more...
.N/A .H4/H2A histone acetyltransferase complex
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 2 5
2014-09-19protein level
1 15 5
2014-05-27protein level
1 15 5
2014-02-25protein level
1 15 5
2013-12-09protein level
1 13 5
2013-11-01protein level
1 13 4
2013-09-12protein level
1 13 4
2013-08-17protein level
1 13 4
2013-07-15protein level
1 10 3
2013-06-11protein level
1 10 3
2013-02-12protein level
1 2 4
2012-12-20protein level
1 2 4
2012-10-30protein level
1 3 4
2012-10-07protein level
1 3 4
2012-08-24protein level
1 2 4
2012-07-28protein level
1 2 4
2012-06-08protein level
1 2 4
2012-05-07protein level
1 1 4
2012-04-10protein level
1 1 4
2012-01-13protein level
1 1 4
2011-12-20protein level
1 1 4
2011-11-11protein level
1 1 4
2011-08-23protein level
1 1 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NV56-1
9 0 0 22402.9185
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-399076,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
2 EBI-399076,EBI-399257 MORF4L2  
  .positive regulation of striated muscle cell differentiation
.positive regulation of transcription from RNA polymerase II promoter
.regulation of growth
  + 4 more...
.N/A .nucleolus
.nucleoplasm
3 EBI-399076,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
4 EBI-399076,EBI-399246 MORF4L1  
  .histone H2A acetylation
.histone H4 acetylation
.regulation of growth
  + 6 more...
.protein N-terminus binding
.chromatin binding
.NuA4 histone acetyltransferase complex
.Sin3 complex
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood73
bone27
brain20
cervix103
connective tissue13
embryonic tissue37
eye23
heart67
intestine25
kidney4
larynx42
liver53
lung44
lymph node77
mammary gland46
muscle18
nerve64
ovary78
pancreas60
parathyroid97
placenta28
prostate21
skin33
spleen18
stomach10
testis126
thymus12
uterus60
Health State
TissuesTPM*
normal33
breast (mammary gland) tumor64
chondrosarcoma24
colorectal tumor26
gastrointestinal tumor42
germ cell tumor41
glioma18
head and neck tumor7
kidney tumor14
leukemia42
liver tumor104
lung tumor9
ovarian tumor78
pancreatic tumor28
primitive neuroectodermal tumor of the CNS31
prostate cancer19
retinoblastoma64
skin tumor47
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult42
embryoid body14
blastocyst32
fetus21
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.3
adrenal gland8.2
appendix8.8
bone marrow6.4
cerebral cortex5.7
colon8.1
duodenum11
esophagus6.1
gallbladder8
heart muscle10.3
kidney7.9
liver4.2
lung6.8
lymph node12.2
ovary12
pancreas4.6
placenta11.5
prostate7.5
salivary gland8.8
skin7.1
small intestine9.2
spleen10.4
stomach8.9
testis65.6
thyroid gland7.5
urinary bladder9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611157, gene) Chromosome 20 open reading frame 20; C20ORF20OMIM


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