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> Protein (NX_Q9NVC3)
Protein (NX_Q9NVC3)
Protein
Gene SymbolSLC38A7 to neXtProt (NX_Q9NVC3)
DescriptionPutative sodium-coupled neutral amino acid transporter 7
Chromosome16
Location16q21 (58699013 ~ 58719008) to Ensembl
Sequene Features : Isoforms 2, Variants 41, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.L-aspartate transmembrane transport
.L-glutamate transmembrane transport
.L-histidine transmembrane transport
  + 10 more...
.L-serine transmembrane transporter activity
.L-methionine transmembrane transporter activity
.L-leucine transmembrane transporter activity
  + 7 more...
.neuronal cell body
.axon
.integral component of membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 41 0
2014-09-19protein level
2 27 0
2014-05-27protein level
2 27 0
2014-02-25protein level
2 27 0
2013-12-09protein level
2 21 0
2013-11-01protein level
2 21 0
2013-09-12protein level
2 21 1
2013-08-17protein level
2 21 1
2013-07-15transcript level
2 11 1
2013-06-11transcript level
2 11 1
2013-02-12transcript level
2 8 2
2012-12-20transcript level
2 7 2
2012-10-30transcript level
2 9 2
2012-10-07transcript level
2 9 1
2012-08-24transcript level
2 7 1
2012-07-28transcript level
2 7 1
2012-06-08transcript level
2 9 1
2012-05-07transcript level
2 9 1
2012-04-10transcript level
2 9 1
2012-01-13transcript level
2 7 1
2011-12-20transcript level
2 7 1
2011-11-11transcript level
2 7 1
2011-08-23transcript level
2 7 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NVC3-1
5 12 0 49932.809
NX_Q9NVC3-2
0 12 0 36879.6369
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10314552,EBI-348482 RNF5  
  .regulation of autophagic vacuole assembly
.ER-associated misfolded protein catabolic process
.protein K48-linked ubiquitination
  + 5 more...
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.mitochondrial membrane
.integral component of membrane
.endoplasmic reticulum membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites25
bladder33
blood32
bone13
bone marrow20
brain75
connective tissue26
embryonic tissue42
esophagus49
eye33
heart33
intestine30
kidney80
larynx42
liver29
lung29
lymph node22
mammary gland26
mouth166
muscle56
nerve64
ovary98
pancreas37
pituitary gland60
placenta42
prostate52
skin56
spleen56
stomach20
testis158
thymus62
thyroid107
trachea19
uterus56
vascular174
Health State
TissuesTPM*
normal56
adrenal tumor158
breast (mammary gland) tumor42
chondrosarcoma12
colorectal tumor26
gastrointestinal tumor25
germ cell tumor167
glioma37
head and neck tumor104
kidney tumor43
leukemia42
liver tumor52
lung tumor38
non-neoplasia31
ovarian tumor26
pancreatic tumor28
primitive neuroectodermal tumor of the CNS31
prostate cancer96
retinoblastoma107
skin tumor47
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult44
embryoid body42
blastocyst32
neonate160
fetus68
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6
adrenal gland7.8
appendix7.3
bone marrow2.1
cerebral cortex9.7
colon4.9
duodenum5
esophagus4.2
gallbladder6.2
heart muscle10.3
kidney5.8
liver5.8
lung5.6
lymph node4.9
ovary4
pancreas1.9
placenta7.6
prostate4.1
salivary gland3.5
skin5
small intestine4.6
spleen8.6
stomach5.3
testis31.2
thyroid gland9.1
urinary bladder7.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614236, gene) Solute carrier family 38 (amino acid transporter), member 7; SLC38A7OMIM


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