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> Protein (NX_Q9NWQ4)
Protein (NX_Q9NWQ4)
Protein
Gene SymbolGPATCH2L to neXtProt (NX_Q9NWQ4)
DescriptionG patch domain-containing protein 2-like
Chromosome14
Location14q24.3 (76618259 ~ 76720685) to Ensembl
Sequene Features : Isoforms 3, Variants 23, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 23 6
2014-09-19protein level
3 43 6
2014-05-27protein level
3 43 6
2014-02-25protein level
3 43 6
2013-12-09protein level
3 37 6
2013-11-01protein level
3 35 6
2013-09-12protein level
3 35 6
2013-08-17protein level
3 35 6
2013-07-15protein level
3 17 6
2013-06-11protein level
3 17 6
2013-02-12protein level
3 10 19
2012-12-20protein level
3 11 19
2012-10-30protein level
3 11 19
2012-10-07protein level
3 11 7
2012-08-24protein level
3 11 7
2012-07-28protein level
3 11 7
2012-06-08protein level
3 16 7
2012-05-07protein level
3 9 7
2012-04-10protein level
3 9 7
2012-01-13protein level
3 8 7
2011-12-20protein level
3 8 7
2011-11-11protein level
3 8 5
2011-08-23protein level
3 5 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NWQ4-1
1 14 0 40025.3617
NX_Q9NWQ4-3
1 21 0 54225.4048
NX_Q9NWQ4-4
2 21 0 53861.2752
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5666657,EBI-744493 ZNF263  
  .negative regulation of transcription, DNA-templated
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.microtubule cytoskeleton
.cytoplasm
.nucleoplasm
.nucleus
2 EBI-5666657,EBI-349968 SUV39H1  
  .cellular response to hypoxia
.rhythmic process
.negative regulation of transcription, DNA-templated
  + 15 more...
.protein N-terminus binding
.histone methyltransferase activity (H3-K9 specific)
.histone methyltransferase activity
  + 5 more...
.rDNA heterochromatin
.chromatin silencing complex
.nucleoplasm
  + 5 more...
3 EBI-5666657,EBI-744864 ZBTB48  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytoplasm
.nucleoplasm
4 EBI-5666657,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
5 EBI-5666657,EBI-2564275 DIP2A  
  .regulation of apoptotic process
.negative regulation of gene expression
.multicellular organismal development
.catalytic activity .cell surface
.nucleus
6 EBI-5666657,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
7 EBI-5666657,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
8 EBI-5666657,EBI-8643207 ZNF398  
  .positive regulation of transcription, DNA-templated
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
9 EBI-5666657,EBI-751409 ZNF473  
  .mRNA 3'-end processing
.gene expression
.histone mRNA metabolic process
  + 4 more...
.metal ion binding
.DNA binding
.Cajal body
.nucleoplasm
10 EBI-5666657,EBI-725997 TRIM41  
  .protein ubiquitination .ligase activity
.zinc ion binding
.cytoplasm
.nucleolus
11 EBI-5666657,EBI-740322 RBPMS  
  .positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
12 EBI-5666657,EBI-742740 ZBTB8A  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
13 EBI-5666657,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
14 EBI-5666657,EBI-739863 KRTAP4-12  
  .N/A .N/A .keratin filament
15 EBI-5666657,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
16 EBI-5666657,EBI-3957793 PRDM14  
  .homeostasis of number of cells within a tissue
.regulation of DNA methylation
.negative regulation of fibroblast growth factor receptor signaling pathway
  + 11 more...
.metal ion binding
.methyltransferase activity
.DNA binding
.nucleoplasm
17 EBI-5666657,EBI-347633 ZNF408  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.identical protein binding
.DNA binding
.nucleus
18 EBI-5666657,EBI-741515 THAP1  
  .regulation of mitotic cell cycle
.cell cycle
.regulation of transcription, DNA-templated
  + 2 more...
.sequence-specific DNA binding
.identical protein binding
.zinc ion binding
.PML body
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
blood40
bone27
bone marrow20
brain25
embryonic tissue37
esophagus49
eye23
intestine47
kidney18
larynx127
liver14
lung29
lymph node11
mammary gland13
mouth30
muscle84
ovary9
pancreas18
placenta38
prostate10
skin9
spleen18
stomach20
testis41
thymus37
thyroid21
trachea38
uterus30
vascular38
Health State
TissuesTPM*
normal26
breast (mammary gland) tumor21
chondrosarcoma24
colorectal tumor62
esophageal tumor57
gastrointestinal tumor25
germ cell tumor11
head and neck tumor44
kidney tumor14
leukemia31
lymphoma27
non-neoplasia41
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS31
prostate cancer19
retinoblastoma21
skin tumor7
Developmental Stage
TissuesTPM*
adult32
blastocyst81
fetus34
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.2
adrenal gland8.9
appendix14.7
bone marrow28
cerebral cortex10
colon8.4
duodenum9
esophagus10.1
gallbladder13.8
heart muscle7.6
kidney8.4
liver4.3
lung9.2
lymph node12.3
ovary10.6
pancreas5.1
placenta11.4
prostate9.6
salivary gland6.2
skin6.8
small intestine8.7
spleen10.8
stomach9.6
testis21.5
thyroid gland11.5
urinary bladder11.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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