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> Protein (NX_Q9NWW6)
Protein (NX_Q9NWW6)
Protein
Gene SymbolNMRK1 to neXtProt (NX_Q9NWW6)
DescriptionNicotinamide riboside kinase 1
Chromosome9
Location9q21.13 (77675489 ~ 77703133) to Ensembl
Sequene Features : Isoforms 2, Variants 12, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.NAD biosynthetic process .ribosylnicotinamide kinase activity
.metal ion binding
.ATP binding
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 12 0
2014-09-19protein level
2 16 0
2014-05-27protein level
2 16 0
2014-02-25protein level
2 16 0
2013-12-09protein level
2 12 0
2013-11-01protein level
2 12 0
2013-09-12protein level
2 12 0
2013-08-17protein level
2 12 0
2013-07-15protein level
2 9 0
2013-06-11protein level
2 9 0
2013-02-12protein level
2 5 0
2012-12-20protein level
2 5 0
2012-10-30protein level
2 6 0
2012-10-07protein level
2 6 0
2012-08-24protein level
2 6 0
2012-07-28protein level
2 6 0
2012-06-08protein level
2 11 0
2012-05-07protein level
2 11 0
2012-04-10protein level
2 11 0
2012-01-13protein level
2 9 0
2011-12-20protein level
2 9 0
2011-11-11protein level
2 9 0
2011-08-23protein level
2 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NWW6-1
2 7 0 23178.3886
NX_Q9NWW6-2
1 7 0 20139.8061
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10315485,EBI-529518 TAX1BP1  
  .innate immune response
.negative regulation of apoptotic process
.negative regulation of type I interferon production
  + 2 more...
.metal ion binding
.kinase binding
.extracellular exosome
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
blood16
bone41
brain16
cervix82
connective tissue20
embryonic tissue4
eye62
heart11
intestine30
kidney23
larynx42
liver14
lung35
mammary gland79
muscle9
nerve64
ovary19
pancreas18
parathyroid145
placenta17
prostate21
skin4
spleen74
stomach41
testis29
thymus25
thyroid21
uterus17
vascular19
Health State
TissuesTPM*
normal24
breast (mammary gland) tumor96
chondrosarcoma48
colorectal tumor17
gastrointestinal tumor33
germ cell tumor3
glioma9
head and neck tumor14
kidney tumor14
leukemia10
liver tumor20
lung tumor9
non-neoplasia31
ovarian tumor52
pancreatic tumor9
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult31
fetus25
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue22.9
adrenal gland16.3
appendix21.9
bone marrow10.3
cerebral cortex11.3
colon20
duodenum23.4
esophagus36.7
gallbladder24.9
heart muscle11.1
kidney36.1
liver36.1
lung27.8
lymph node26.1
ovary27.5
pancreas25.5
placenta22.1
prostate21.2
salivary gland33.8
skin36.8
small intestine29.4
spleen28.3
stomach24.8
testis11.6
thyroid gland37.5
urinary bladder29
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608704, gene) Nicotinamide riboside kinase 1OMIM


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