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> Protein (NX_Q9NX01)
Protein (NX_Q9NX01)
Protein
Gene SymbolTXNL4B to neXtProt (NX_Q9NX01)
DescriptionThioredoxin-like protein 4B
Chromosome16
Location16q22.2 (72078188 ~ 72128330) to Ensembl
Sequene Features : Isoforms 1, Variants 20, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mitotic nuclear division
.spliceosomal complex assembly
.N/A .U4/U6 x U5 tri-snRNP complex
.U5 snRNP
.spliceosomal complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 20 1
2014-09-19protein level
1 16 1
2014-05-27protein level
1 16 1
2014-02-25protein level
1 16 1
2013-12-09protein level
1 13 1
2013-11-01protein level
1 12 1
2013-09-12protein level
1 12 1
2013-08-17protein level
1 12 1
2013-07-15protein level
1 9 1
2013-06-11protein level
1 9 1
2013-02-12protein level
1 5 1
2012-12-20protein level
1 4 1
2012-10-30protein level
1 6 1
2012-10-07protein level
1 6 1
2012-08-24protein level
1 3 1
2012-07-28protein level
1 3 1
2012-06-08protein level
1 3 1
2012-05-07protein level
1 3 1
2012-04-10protein level
1 3 1
2012-01-13protein level
1 1 1
2011-12-20protein level
1 1 1
2011-11-11protein level
1 1 1
2011-08-23protein level
1 1 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NX01-1
6 0 0 17003.7573
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10309345,EBI-711810 BHLHE40  
  .negative regulation of transcription, DNA-templated
.negative regulation of sequence-specific DNA binding transcription factor activity
.entrainment of circadian clock by photoperiod
  + 4 more...
.E-box binding
.protein heterodimerization activity
.MRF binding
  + 10 more...
.Golgi apparatus
.nucleolus
.nucleoplasm
.nucleus
2 EBI-10309345,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
3 EBI-10309345,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
4 EBI-10309345,EBI-10171633 PNMA5  
  .positive regulation of apoptotic process .identical protein binding .N/A
5 EBI-10309345,EBI-742388 PLEKHF2  
  .protein transport .metal ion binding .early endosome membrane
.transport vesicle
.endoplasmic reticulum
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
bladder33
blood65
bone27
bone marrow20
brain44
cervix20
connective tissue33
embryonic tissue32
esophagus49
eye19
heart44
intestine43
kidney71
liver19
lung17
lymph node66
mammary gland19
mouth30
muscle9
ovary19
pharynx49
placenta17
prostate26
salivary gland49
skin23
spleen74
stomach41
testis27
thymus25
thyroid21
trachea57
uterus25
vascular38
Health State
TissuesTPM*
normal33
breast (mammary gland) tumor32
cervical tumor28
chondrosarcoma48
colorectal tumor53
esophageal tumor57
gastrointestinal tumor59
germ cell tumor79
glioma9
head and neck tumor29
kidney tumor43
leukemia84
liver tumor41
lung tumor9
non-neoplasia10
ovarian tumor26
primitive neuroectodermal tumor of the CNS7
prostate cancer19
skin tumor39
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult26
blastocyst48
fetus50
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.8
adrenal gland6.4
appendix8.2
bone marrow7.3
cerebral cortex8.6
colon6.5
duodenum7.4
esophagus6
gallbladder7.1
heart muscle5
kidney6.4
liver6.5
lung5.6
lymph node9.2
ovary17
pancreas3.8
placenta6.1
prostate6.6
salivary gland5.2
skin5.7
small intestine7
spleen6.7
stomach7.4
testis14.5
thyroid gland6.7
urinary bladder6.4
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)


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