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> Protein (NX_Q9NX58)
Protein (NX_Q9NX58)
Protein
Gene SymbolLYAR to neXtProt (NX_Q9NX58)
DescriptionCell growth-regulating nucleolar protein
Chromosome4
Location4p16.3 (4269428 ~ 4291896) to Ensembl
Sequene Features : Isoforms 1, Variants 53, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .metal ion binding
.poly(A) RNA binding
.nucleolus
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 53 5
2014-09-19protein level
1 42 5
2014-05-27protein level
1 42 5
2014-02-25protein level
1 42 5
2013-12-09protein level
1 32 5
2013-11-01protein level
1 32 5
2013-09-12protein level
1 32 5
2013-08-17protein level
1 32 5
2013-07-15protein level
1 24 5
2013-06-11protein level
1 24 5
2013-02-12protein level
1 20 6
2012-12-20protein level
1 19 6
2012-10-30protein level
1 23 6
2012-10-07protein level
1 23 6
2012-08-24protein level
1 21 6
2012-07-28protein level
1 21 6
2012-06-08protein level
1 22 6
2012-05-07protein level
1 22 6
2012-04-10protein level
1 22 6
2012-01-13protein level
1 12 6
2011-12-20protein level
1 12 6
2011-11-11protein level
1 12 4
2011-08-23protein level
1 12 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NX58-1
15 0 0 43587.7352
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-713507,EBI-713955 PRKRA  
  .positive regulation of intrinsic apoptotic signaling pathway
.skeletal system morphogenesis
.positive regulation of catalytic activity
  + 11 more...
.poly(A) RNA binding
.protein homodimerization activity
.identical protein binding
  + 3 more...
.perinuclear region of cytoplasm
.membrane
.cytosol
  + 2 more...
2 EBI-713507,EBI-10181188 BEND7  
  .N/A .N/A .extracellular exosome
3 EBI-713507,EBI-742426 SDCBP2  
  .intracellular transport
.intracellular signal transduction
.nervous system development
.protein heterodimerization activity
.protein homodimerization activity
.protein C-terminus binding
.extracellular exosome
.plasma membrane
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites125
bladder33
blood16
bone83
bone marrow41
brain5
cervix20
connective tissue60
embryonic tissue14
esophagus99
eye14
heart22
intestine30
kidney28
liver19
lung11
lymph22
lymph node11
mammary gland26
ovary9
pancreas9
pharynx24
placenta24
prostate10
skin9
stomach10
testis87
uterus30
vascular38
Health State
TissuesTPM*
normal18
bladder carcinoma56
breast (mammary gland) tumor42
cervical tumor28
chondrosarcoma60
colorectal tumor35
esophageal tumor115
gastrointestinal tumor42
germ cell tumor22
glioma9
kidney tumor14
leukemia42
liver tumor20
lymphoma13
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS39
prostate cancer9
retinoblastoma43
skin tumor7
soft tissue/muscle tissue tumor87
uterine tumor11
Developmental Stage
TissuesTPM*
adult26
embryoid body14
blastocyst16
fetus35
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.3
adrenal gland9.3
appendix20.6
bone marrow12.8
cerebral cortex5
colon11.5
duodenum7.9
esophagus13.9
gallbladder8.9
heart muscle12.1
kidney5.3
liver6.2
lung11.8
lymph node23.3
ovary11.5
pancreas4.2
placenta10.2
prostate9
salivary gland4.7
skin8.6
small intestine7.6
spleen18.6
stomach8.3
testis101.2
thyroid gland6.4
urinary bladder11.2
Tissues
TissuesExpression level
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderMedium
hippocampusMedium
kidneyHigh
lateral ventricleHigh
liverMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleLow
skeletal muscleMedium
skin 1High
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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