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> Protein (NX_Q9NYP9)
Protein (NX_Q9NYP9)
Protein
Gene SymbolMIS18A to neXtProt (NX_Q9NYP9)
DescriptionProtein Mis18-alpha
Chromosome21
Location21q22.11 (33640530 ~ 33651380) to Ensembl
Sequene Features : Isoforms 1, Variants 17, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of protein targeting to mitochondrion
.cell division
.regulation of DNA methylation
  + 4 more...
.N/A .cytoplasm
.nucleoplasm
.nucleus
.chromosome, centromeric region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 17 8
2014-09-19protein level
1 14 8
2014-05-27protein level
1 14 8
2014-02-25protein level
1 14 8
2013-12-09protein level
1 9 8
2013-11-01protein level
1 9 8
2013-09-12protein level
1 9 8
2013-08-17protein level
1 9 8
2013-07-15protein level
1 6 3
2013-06-11protein level
1 6 3
2013-02-12protein level
1 4 2
2012-12-20protein level
1 3 2
2012-10-30protein level
1 5 2
2012-10-07protein level
1 5 2
2012-08-24protein level
1 4 2
2012-07-28protein level
1 4 2
2012-06-08protein level
1 9 2
2012-05-07protein level
1 9 2
2012-04-10protein level
1 9 2
2012-01-13protein level
1 8 2
2011-12-20protein level
1 8 2
2011-11-11protein level
1 8 2
2011-08-23protein level
1 8 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NYP9-1
10 0 0 25846.3789
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1104552,EBI-536879 OIP5  
  .cell division
.CENP-A containing nucleosome assembly
.cell communication
  + 2 more...
.N/A .Cajal body
.chromocenter
.cytoplasm
  + 4 more...
2 EBI-1104552,EBI-745226 AIMP2  
  .Type II pneumocyte differentiation
.positive regulation of protein ubiquitination
.gene expression
  + 3 more...
.N/A .membrane
.cytosol
.nucleus
3 EBI-1104552,EBI-10304361 BRD8  
  .histone H2A acetylation
.histone H4 acetylation
.regulation of growth
  + 6 more...
.thyroid hormone receptor activity
.sequence-specific DNA binding transcription factor activity
.NuA4 histone acetyltransferase complex
.mitochondrion
.nucleoplasm
  + 2 more...
4 EBI-1104552,EBI-10182361 MBIP  
  .histone H3 acetylation
.chromatin organization
.inactivation of MAPK activity involved in osmosensory signaling pathway
.identical protein binding
.protein kinase inhibitor activity
.cytoplasm
.nucleolus
.Ada2/Gcn5/Ada3 transcription activator complex
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites100
blood32
bone69
bone marrow41
brain1
connective tissue20
ear62
embryonic tissue28
esophagus49
eye33
heart111
intestine25
kidney14
liver14
lung56
lymph135
lymph node167
mammary gland13
mouth15
muscle9
ovary19
pancreas14
parathyroid145
placenta10
prostate68
salivary gland49
skin47
stomach31
testis43
tonsil58
uterus12
vascular19
Health State
TissuesTPM*
normal28
breast (mammary gland) tumor21
chondrosarcoma96
colorectal tumor17
esophageal tumor57
gastrointestinal tumor50
germ cell tumor22
glioma9
head and neck tumor7
kidney tumor29
leukemia31
liver tumor31
lung tumor9
lymphoma83
non-neoplasia10
ovarian tumor26
pancreatic tumor9
prostate cancer9
retinoblastoma43
skin tumor79
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult19
embryoid body28
blastocyst16
fetus50
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.4
adrenal gland5
appendix8.2
bone marrow9.9
cerebral cortex3.4
colon9.7
duodenum6.9
esophagus5.5
gallbladder3.4
heart muscle2.8
kidney5.6
liver3
lung3.7
lymph node10.2
ovary8.9
pancreas1.6
placenta6.7
prostate5.6
salivary gland3.8
skin7
small intestine7.8
spleen5.4
stomach5.6
testis20.3
thyroid gland3.2
urinary bladder5.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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