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> Protein (NX_Q9NZM4)
Protein (NX_Q9NZM4)
Protein
Gene SymbolGLTSCR1 to neXtProt (NX_Q9NZM4)
DescriptionGlioma tumor suppressor candidate region gene 1 protein
Chromosome19
Location19q13.33 (48111453 ~ 48206533) to Ensembl
Sequene Features : Isoforms 2, Variants 80, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 80 3
2014-09-19protein level
2 65 3
2014-05-27protein level
2 65 3
2014-02-25protein level
2 65 3
2013-12-09protein level
2 49 3
2013-11-01protein level
2 49 3
2013-09-12protein level
2 49 3
2013-08-17protein level
2 49 3
2013-07-15protein level
2 31 3
2013-06-11protein level
2 31 3
2013-02-12protein level
2 13 4
2012-12-20protein level
2 16 4
2012-10-30protein level
2 17 4
2012-10-07protein level
2 17 2
2012-08-24protein level
2 17 2
2012-07-28protein level
2 17 2
2012-06-08protein level
2 17 2
2012-05-07protein level
2 12 2
2012-04-10protein level
2 12 2
2012-01-13protein level
2 12 2
2011-12-20protein level
2 12 2
2011-11-11protein level
2 12 2
2011-08-23protein level
2 12 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NZM4-1
3 41 0 158392.3879
NX_Q9NZM4-2
1 41 0 134123.504
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1754943,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood16
bone13
brain11
cervix41
embryonic tissue56
eye9
lung5
lymph67
lymph node11
mammary gland13
muscle9
ovary19
pancreas32
placenta10
prostate10
spleen18
testis4
uterus12
Health State
TissuesTPM*
normal14
germ cell tumor3
glioma46
leukemia10
lymphoma41
ovarian tumor26
pancreatic tumor9
primitive neuroectodermal tumor of the CNS15
prostate cancer19
soft tissue/muscle tissue tumor15
uterine tumor22
Developmental Stage
TissuesTPM*
adult8
embryoid body71
blastocyst32
fetus21
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.5
adrenal gland4.8
appendix6.7
bone marrow4.5
cerebral cortex4.5
colon5.5
duodenum8.5
esophagus6.1
gallbladder5.6
heart muscle3.7
kidney4.5
liver1.9
lung5.2
lymph node7.8
ovary11.3
pancreas1.6
placenta6.8
prostate6.1
salivary gland3.8
skin5.3
small intestine7.6
spleen7.4
stomach5
testis4.4
thyroid gland6.4
urinary bladder6.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605690, gene) Glioma tumor suppressor candidate region gene 1; GLTSCR1OMIM


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