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> Protein (NX_Q9NZZ3)
Protein (NX_Q9NZZ3)
Protein
Gene SymbolCHMP5 to neXtProt (NX_Q9NZZ3)
DescriptionCharged multivesicular body protein 5
Chromosome9
Location9p13.3 (33264940 ~ 33281977) to Ensembl
Sequene Features : Isoforms 2, Variants 19, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of mitotic spindle assembly
.multivesicular body sorting pathway
.membrane organization
  + 12 more...
.N/A .extracellular exosome
.endosome membrane
.cytosol
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 19 4
2014-09-19protein level
2 16 4
2014-05-27protein level
2 16 4
2014-02-25protein level
2 16 4
2013-12-09protein level
2 13 4
2013-11-01protein level
2 13 2
2013-09-12protein level
2 13 2
2013-08-17protein level
2 13 2
2013-07-15protein level
2 9 1
2013-06-11protein level
2 9 1
2013-02-12protein level
2 2 3
2012-12-20protein level
2 2 3
2012-10-30protein level
2 3 3
2012-10-07protein level
2 3 2
2012-08-24protein level
2 3 2
2012-07-28protein level
2 3 2
2012-06-08protein level
2 7 2
2012-05-07protein level
2 7 2
2012-04-10protein level
2 7 2
2012-01-13protein level
1 7 2
2011-12-20protein level
1 7 2
2011-11-11protein level
1 7 1
2011-08-23protein level
1 7 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9NZZ3-1
2 3 0 24555.2847
NX_Q9NZZ3-2
1 3 0 19507.8172
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751303,EBI-2514459 VPS4B  
  .positive regulation of viral life cycle
.positive regulation of centriole elongation
.positive regulation of exosomal secretion
  + 27 more...
.protein homodimerization activity
.identical protein binding
.ATPase activity, coupled
  + 3 more...
.Flemming body
.extracellular exosome
.late endosome membrane
  + 7 more...
2 EBI-751303,EBI-396676 STAMBP  
  .negative regulation of Ras protein signal transduction
.negative regulation of neuron apoptotic process
.protein deubiquitination
  + 4 more...
.metal ion binding
.protein domain specific binding
.metallopeptidase activity
.ubiquitin-specific protease activity
.extracellular exosome
.cleavage furrow
.plasma membrane
  + 4 more...
3 EBI-751303,EBI-2691489 MITD1  
  .negative regulation of protein binding
.transport
.cell separation after cytokinesis
.mitotic cytokinesis
.protein homodimerization activity
.phosphatidylinositol binding
.protein domain specific binding
.extracellular exosome
.intracellular membrane-bounded organelle
.late endosome membrane
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland182
ascites100
bladder1004
blood57
bone125
bone marrow636
brain136
cervix82
connective tissue100
ear124
embryonic tissue126
eye90
heart78
intestine56
kidney147
larynx127
liver63
lung80
lymph67
lymph node44
mammary gland52
mouth15
muscle84
nerve64
ovary39
pancreas121
parathyroid97
pharynx245
pituitary gland121
placenta77
prostate211
salivary gland592
skin128
spleen37
stomach20
testis156
thyroid64
trachea19
uterus86
vascular154
Health State
TissuesTPM*
normal85
adrenal tumor395
bladder carcinoma1876
breast (mammary gland) tumor32
cervical tumor57
chondrosarcoma120
colorectal tumor44
gastrointestinal tumor50
germ cell tumor155
glioma251
head and neck tumor52
kidney tumor217
leukemia306
liver tumor52
lung tumor19
lymphoma83
non-neoplasia20
ovarian tumor26
pancreatic tumor104
primitive neuroectodermal tumor of the CNS23
prostate cancer260
retinoblastoma150
skin tumor191
soft tissue/muscle tissue tumor175
uterine tumor77
Developmental Stage
TissuesTPM*
adult77
embryoid body171
blastocyst65
fetus55
infant42
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue44.2
adrenal gland64.5
appendix46.8
bone marrow23.1
cerebral cortex58.8
colon69.3
duodenum60.5
esophagus60.9
gallbladder57.9
heart muscle48.9
kidney75.5
liver33.4
lung57.4
lymph node50.2
ovary39.6
pancreas17
placenta69.5
prostate64.5
salivary gland35.6
skin38.5
small intestine66
spleen46.1
stomach58.1
testis37.5
thyroid gland70.9
urinary bladder66.9
Tissues
TissuesExpression level
adrenal glandLow
appendixMedium
breastLow
bronchusHigh
cerebral cortexLow
colonMedium
duodenumHigh
fallopian tubeLow
gallbladderHigh
heart muscleLow
kidneyMedium
lateral ventricleMedium
pancreasMedium
placentaLow
prostateLow
rectumMedium
seminal vesicleMedium
small intestineHigh
stomach 1Medium
stomach 2Medium
testisLow
thyroid glandLow
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610900, gene) Chmp family, member 5; CHMP5OMIM


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