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> Protein (NX_Q9P127)
Protein (NX_Q9P127)
Protein
Gene SymbolLUZP4 to neXtProt (NX_Q9P127)
DescriptionLeucine zipper protein 4
ChromosomeX
LocationXq23 (114524293 ~ 114542121) to Ensembl
Sequene Features : Isoforms 2, Variants 81, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 81 0
2014-09-19protein level
2 62 0
2014-05-27protein level
2 57 0
2014-02-25protein level
1 56 0
2013-12-09protein level
1 47 0
2013-11-01protein level
1 40 0
2013-09-12protein level
1 40 0
2013-08-17protein level
1 40 0
2013-07-15transcript level
1 26 0
2013-06-11transcript level
1 26 0
2013-02-12transcript level
1 17 0
2012-12-20transcript level
1 14 0
2012-10-30transcript level
1 20 0
2012-10-07transcript level
1 20 0
2012-08-24transcript level
1 20 0
2012-07-28transcript level
1 20 0
2012-06-08transcript level
1 17 0
2012-05-07transcript level
1 17 0
2012-04-10transcript level
1 17 0
2012-01-13transcript level
1 3 0
2011-12-20transcript level
1 3 0
2011-11-11transcript level
1 3 0
2011-08-23transcript level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9P127-1
6 5 0 35915.5326
NX_Q9P127-2
1 5 0 26518.0503
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10198848,EBI-3893419 FOSL2  
  .response to cAMP
.response to corticosterone
.positive regulation of fibroblast proliferation
  + 9 more...
.sequence-specific DNA binding transcription factor activity
.double-stranded DNA binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleoplasm
.nucleus
2 EBI-10198848,EBI-750020 CLK2  
  .protein autophosphorylation
.negative regulation of gluconeogenesis
.regulation of RNA splicing
  + 3 more...
.ATP binding
.protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity
.nuclear speck
.nucleoplasm
.nucleus
3 EBI-10198848,EBI-489887 EMD  
  .cellular response to growth factor stimulus
.regulation of canonical Wnt signaling pathway
.negative regulation of fibroblast proliferation
  + 8 more...
.beta-tubulin binding
.actin binding
.nuclear membrane
.integral component of membrane
.membrane
  + 5 more...
4 EBI-10198848,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
5 EBI-10198848,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
6 EBI-10198848,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
7 EBI-10198848,EBI-593303 SRPK2  
  .regulation of mRNA splicing, via spliceosome
.positive regulation of cell cycle
.innate immune response
  + 12 more...
.14-3-3 protein binding
.poly(A) RNA binding
.ATP binding
  + 2 more...
.cytoplasm
.nucleolus
.nucleoplasm
.nucleus
8 EBI-10198848,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
9 EBI-10198848,EBI-743428 RCOR3  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.chromatin binding
.DNA binding
.nucleus
10 EBI-10198848,EBI-740492 TLK1  
  .intracellular signal transduction
.chromatin modification
.cell cycle
  + 4 more...
.ATP binding
.protein serine/threonine kinase activity
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
testis16
Health State
TissuesTPM*
normal2
Developmental Stage
TissuesTPM*
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis8.5
Tissues
TissuesExpression level
testisMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300616, gene) Leucine zipper protein 4; LUZP4OMIM


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