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> Protein (NX_Q9P1A6)
Protein (NX_Q9P1A6)
Protein
Gene SymbolDLGAP2 to neXtProt (NX_Q9P1A6)
DescriptionDisks large-associated protein 2
Chromosome8
Location8p23.3 (1449532 ~ 1656642) to Ensembl
Sequene Features : Isoforms 3, Variants 177, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.neuron-neuron synaptic transmission .N/A .postsynaptic membrane
.cell junction
.postsynaptic density
.neurofilament
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 177 1
2014-09-19protein level
3 134 1
2014-05-27protein level
3 134 1
2014-02-25protein level
3 132 1
2013-12-09protein level
3 108 1
2013-11-01protein level
3 107 1
2013-09-12protein level
3 107 10
2013-08-17protein level
3 107 10
2013-07-15protein level
3 73 10
2013-06-11protein level
3 73 10
2013-02-12protein level
3 22 30
2012-12-20protein level
3 22 30
2012-10-30protein level
3 28 30
2012-10-07protein level
3 28 10
2012-08-24protein level
3 24 10
2012-07-28protein level
3 24 10
2012-06-08protein level
3 3 10
2012-05-07protein level
3 3 10
2012-04-10protein level
3 3 10
2012-01-13protein level
3 3 10
2011-12-20protein level
3 3 10
2011-11-11protein level
3 3 10
2011-08-23protein level
3 3 10
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9P1A6-1
0 40 2 117545.9511
NX_Q9P1A6-2
1 38 2 115861.2437
NX_Q9P1A6-3
0 37 2 108839.9863
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1753397,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
2 EBI-1753397,EBI-401755 GRB2  
  .positive regulation of reactive oxygen species metabolic process
.cellular response to ionizing radiation
.branching involved in labyrinthine layer morphogenesis
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.insulin receptor substrate binding
  + 6 more...
.Grb2-EGFR complex
.extracellular exosome
.vesicle membrane
  + 10 more...
3 EBI-1753397,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
4 EBI-1753397,EBI-10172511 KRTAP4-2  
  .N/A .N/A .keratin filament
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
brain6
kidney4
lung8
mouth45
testis18
uterus4
Health State
TissuesTPM*
normal7
germ cell tumor15
head and neck tumor22
leukemia10
lung tumor9
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult5
fetus16
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
cerebral cortex3.2
kidney2.1
testis8.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605438, gene) Discs large-associated protein 2; DLGAP2OMIM


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