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> Protein (NX_Q9P2H0)
Protein (NX_Q9P2H0)
Protein
Gene SymbolKIAA1377 to neXtProt (NX_Q9P2H0)
DescriptionUncharacterized protein KIAA1377
Chromosome11
Location11q22.1 (101785746 ~ 101871789) to Ensembl
Sequene Features : Isoforms 1, Variants 178, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cilium assembly
.cytoplasmic microtubule organization
.mitotic spindle organization
.N/A .ciliary base
.midbody
.centrosome
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 178 0
2014-09-19protein level
1 131 0
2014-05-27protein level
1 131 0
2014-02-25protein level
1 130 0
2013-12-09protein level
1 105 0
2013-11-01protein level
1 102 0
2013-09-12protein level
1 102 0
2013-08-17protein level
1 102 0
2013-07-15protein level
1 76 0
2013-06-11protein level
1 76 0
2013-02-12protein level
1 45 0
2012-12-20protein level
1 45 0
2012-10-30protein level
1 52 0
2012-10-07protein level
1 52 0
2012-08-24protein level
1 47 0
2012-07-28protein level
1 47 0
2012-06-08protein level
1 48 0
2012-05-07protein level
1 37 0
2012-04-10protein level
1 37 0
2012-01-13protein level
1 22 0
2011-12-20protein level
1 22 0
2011-11-11protein level
1 22 0
2011-08-23protein level
1 22 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9P2H0-1
50 0 0 125792.4533
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-473176,EBI-473199 KAT7  
  .histone H4-K12 acetylation
.histone H4-K8 acetylation
.histone H4-K5 acetylation
  + 5 more...
.zinc ion binding
.histone acetyltransferase activity
.sequence-specific DNA binding transcription factor activity
.cytoplasm
.nucleoplasm
.histone acetyltransferase complex
2 EBI-473176,EBI-448202 GADD45G  
  .positive regulation of p38MAPK cascade
.regulation of cell cycle
.positive regulation of JNK cascade
  + 8 more...
.N/A .cytoplasm
.nucleus
3 EBI-473176,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
4 EBI-473176,EBI-399080 KAT5  
  .positive regulation of protein acetylation
.cellular response to estradiol stimulus
.positive regulation of transcription from RNA polymerase II promoter
  + 14 more...
.repressing transcription factor binding
.androgen receptor binding
.metal ion binding
  + 2 more...
.perinuclear region of cytoplasm
.NuA4 histone acetyltransferase complex
.Piccolo NuA4 histone acetyltransferase complex
  + 6 more...
5 EBI-473176,EBI-396435 FEZ1  
  .cellular response to growth factor stimulus
.establishment of mitochondrion localization
.positive regulation of neuron projection development
  + 4 more...
.N/A .dendrite
.axon
.microtubule cytoskeleton
  + 5 more...
6 EBI-473176,EBI-473181 BARD1  
  .protein K6-linked ubiquitination
.negative regulation of protein export from nucleus
.positive regulation of protein catabolic process
  + 9 more...
.protein heterodimerization activity
.protein homodimerization activity
.kinase binding
  + 4 more...
.BRCA1-A complex
.intracellular membrane-bounded organelle
.BRCA1-BARD1 complex
  + 5 more...
7 EBI-473176,EBI-466061 GIT1  
  .ephrin receptor signaling pathway
.regulation of cytokinesis
.regulation of G-protein coupled receptor protein signaling pathway
.axon guidance
.zinc ion binding
.GTPase activator activity
.aggresome
.membrane
.focal adhesion
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone27
brain19
connective tissue20
embryonic tissue28
eye23
heart11
intestine8
lung32
mouth15
muscle37
ovary9
pancreas70
parathyroid48
pituitary gland181
testis57
trachea77
uterus12
Health State
TissuesTPM*
normal21
chondrosarcoma12
colorectal tumor8
germ cell tumor3
head and neck tumor7
pancreatic tumor28
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult14
embryoid body28
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.7
adrenal gland5.9
appendix1.4
cerebral cortex5.7
colon2
esophagus3.4
gallbladder3.8
heart muscle1.4
kidney2.1
lung4.5
lymph node1.7
ovary7.8
placenta1.1
prostate2
salivary gland1.1
skin2.5
small intestine1.3
spleen1.4
stomach2.6
testis18.6
thyroid gland4.5
urinary bladder2.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614634, gene) Kiaa1377 gene; KIAA1377OMIM


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