Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9P2M4)
Protein (NX_Q9P2M4)
Protein
Gene SymbolTBC1D14 to neXtProt (NX_Q9P2M4)
DescriptionTBC1 domain family member 14
Chromosome4
Location4p16.1 (6910969 ~ 7034845) to Ensembl
Sequene Features : Isoforms 2, Variants 75, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of autophagic vacuole assembly
.recycling endosome to Golgi transport
.negative regulation of autophagy
.protein kinase binding
.GTPase activator activity
.recycling endosome
.Golgi apparatus
.autophagic vacuole
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 75 2
2014-09-19protein level
2 60 2
2014-05-27protein level
2 59 2
2014-02-25protein level
2 58 2
2013-12-09protein level
2 50 2
2013-11-01protein level
2 47 2
2013-09-12protein level
2 47 2
2013-08-17protein level
2 47 2
2013-07-15protein level
2 32 2
2013-06-11protein level
2 32 2
2013-02-12protein level
2 17 0
2012-12-20protein level
2 15 0
2012-10-30protein level
2 17 0
2012-10-07protein level
2 17 0
2012-08-24protein level
2 17 0
2012-07-28protein level
2 17 0
2012-06-08protein level
2 17 0
2012-05-07protein level
2 14 0
2012-04-10protein level
2 15 0
2012-01-13protein level
2 7 0
2011-12-20protein level
2 7 0
2011-11-11protein level
2 7 0
2011-08-23protein level
2 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9P2M4-1
8 14 3 78087.702
NX_Q9P2M4-2
0 14 3 47660.1659
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2797718,EBI-908831 ULK1  
  .regulation of neurotrophin TRK receptor signaling pathway
.axon extension
.negative regulation of collateral sprouting
  + 15 more...
.protein complex binding
.Rab GTPase binding
.ATP binding
.protein serine/threonine kinase activity
.extrinsic component of autophagic vacuole membrane
.extrinsic component of pre-autophagosomal structure membrane
.extrinsic component of omegasome membrane
  + 9 more...
2 EBI-2797718,EBI-722234 RAB11B  
  .regulation of endocytic recycling
.regulation of protein localization to cell surface
.retrograde transport, endosome to plasma membrane
  + 11 more...
.myosin V binding
.GDP binding
.GTP binding
.GTPase activity
.extracellular exosome
.recycling endosome membrane
.recycling endosome
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
blood57
bone83
brain64
connective tissue53
embryonic tissue65
esophagus49
eye23
heart11
intestine30
kidney61
lung38
lymph node167
mouth30
muscle28
nerve64
ovary39
pancreas42
parathyroid194
pharynx24
placenta42
prostate121
skin28
stomach41
testis82
thymus75
trachea96
uterus81
Health State
TissuesTPM*
normal57
chondrosarcoma108
colorectal tumor35
esophageal tumor57
gastrointestinal tumor42
germ cell tumor110
glioma65
head and neck tumor14
kidney tumor29
leukemia84
lung tumor9
lymphoma13
non-neoplasia31
ovarian tumor65
pancreatic tumor57
primitive neuroectodermal tumor of the CNS7
prostate cancer96
skin tumor23
soft tissue/muscle tissue tumor15
uterine tumor77
Developmental Stage
TissuesTPM*
adult53
embryoid body100
blastocyst81
fetus75
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.3
adrenal gland32.6
appendix28.2
bone marrow8.8
cerebral cortex34.7
colon25.8
duodenum17.9
esophagus27.6
gallbladder16.8
heart muscle21.5
kidney39.9
liver5.4
lung22.3
lymph node26.5
ovary25.4
pancreas8.5
placenta19.8
prostate22
salivary gland21.8
skin34.9
small intestine21
spleen25.4
stomach26.9
testis34.1
thyroid gland19.7
urinary bladder22.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614855, gene) Tbc1 domain family, member 14; TBC1D14OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center