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> Protein (NX_Q9P2N2)
Protein (NX_Q9P2N2)
Protein
Gene SymbolARHGAP28 to neXtProt (NX_Q9P2N2)
DescriptionRho GTPase-activating protein 28
Chromosome18
Location18p11.31 (6729717 ~ 6915715) to Ensembl
Sequene Features : Isoforms 4, Variants 133, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of small GTPase mediated signal transduction
.small GTPase mediated signal transduction
.GTPase activator activity .cell junction
.cytosol
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 133 2
2014-09-19protein level
4 101 2
2014-05-27protein level
4 100 2
2014-02-25protein level
4 99 2
2013-12-09protein level
4 81 2
2013-11-01protein level
4 75 2
2013-09-12protein level
4 75 4
2013-08-17protein level
4 75 4
2013-07-15protein level
4 52 4
2013-06-11protein level
4 52 4
2013-02-12protein level
4 29 8
2012-12-20protein level
4 34 8
2012-10-30protein level
4 35 8
2012-10-07protein level
4 35 4
2012-08-24protein level
4 33 4
2012-07-28protein level
4 33 4
2012-06-08protein level
4 4 4
2012-05-07protein level
4 4 4
2012-04-10protein level
4 4 4
2012-01-13protein level
4 4 4
2011-12-20protein level
4 4 4
2011-11-11protein level
4 4 4
2011-08-23protein level
4 4 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9P2N2-1
3 28 1 82007.8557
NX_Q9P2N2-2
0 28 1 75721.9616
NX_Q9P2N2-3
0 22 0 61916.3388
NX_Q9P2N2-5
0 23 0 64574.4965
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
brain10
connective tissue13
embryonic tissue56
eye9
heart44
kidney18
liver9
lung5
mouth15
muscle9
ovary9
pancreas4
placenta38
prostate5
skin4
spleen18
stomach10
testis259
Health State
TissuesTPM*
normal42
chondrosarcoma24
germ cell tumor18
liver tumor10
pancreatic tumor9
prostate cancer9
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult16
embryoid body128
blastocyst48
fetus62
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.4
adrenal gland2
appendix2.2
colon2.3
duodenum1.9
esophagus3.5
gallbladder8.8
heart muscle2
kidney9.1
lung5.5
lymph node2
ovary12
pancreas2.2
placenta21.2
prostate3.7
skin2
small intestine2.3
spleen13.8
stomach2
testis65.8
thyroid gland3.7
urinary bladder8.7
Tissues
TissuesExpression level
heart muscleLow
kidneyLow
skeletal muscleLow
skin 1Low
testisMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610592, gene) Rho gtpase-activating protein 28; ARHGAP28OMIM


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