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> Protein (NX_Q9UBK9)
Protein (NX_Q9UBK9)
Protein
Gene SymbolUXT to neXtProt (NX_Q9UBK9)
DescriptionProtein UXT
ChromosomeX
LocationXp11.23 (47511197 ~ 47518560) to Ensembl
Sequene Features : Isoforms 1, Variants 13, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.centrosome organization
.mitochondrion transport along microtubule
.microtubule cytoskeleton organization
.negative regulation of transcription from RNA polymerase II promoter
.beta-tubulin binding
.microtubule binding
.chromatin binding
.RNA polymerase II transcription corepressor activity
.cytoskeleton
.centrosome
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 13 6
2014-09-19protein level
1 9 6
2014-05-27protein level
1 9 6
2014-02-25protein level
1 9 6
2013-12-09protein level
1 5 6
2013-11-01protein level
1 5 4
2013-09-12protein level
1 5 4
2013-08-17protein level
1 5 4
2013-07-15protein level
1 4 1
2013-06-11protein level
1 4 1
2013-02-12protein level
1 2 1
2012-12-20protein level
1 2 1
2012-10-30protein level
1 2 1
2012-10-07protein level
1 2 1
2012-08-24protein level
1 2 1
2012-07-28protein level
1 2 1
2012-06-08protein level
1 4 1
2012-05-07protein level
1 4 1
2012-04-10protein level
1 4 1
2012-01-13protein level
1 2 1
2011-12-20protein level
1 2 1
2011-11-11protein level
1 2 1
2011-08-23protein level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UBK9-1
7 0 0 18234.5577
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-357355,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
2 EBI-357355,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
3 EBI-357355,EBI-1384862 MECOM  
  .renal system development
.hematopoietic stem cell proliferation
.pericardium development
  + 19 more...
.metal ion binding
.protein homodimerization activity
.sequence-specific DNA binding transcription factor activity
.DNA binding
.intracellular membrane-bounded organelle
.nuclear speck
.aggresome
  + 5 more...
4 EBI-357355,EBI-73886 RELA  
  .negative regulation of extrinsic apoptotic signaling pathway
.positive regulation of miRNA metabolic process
.negative regulation of NIK/NF-kappaB signaling
  + 64 more...
.repressing transcription factor binding
.NF-kappaB binding
.protein N-terminus binding
  + 20 more...
.NF-kappaB complex
.I-kappaB/NF-kappaB complex
.cytosol
  + 4 more...
5 EBI-357355,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
6 EBI-357355,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
7 EBI-357355,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
8 EBI-357355,EBI-747107 SIAH1  
  .positive regulation of intrinsic apoptotic signaling pathway
.neuron apoptotic process
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 11 more...
.ubiquitin protein ligase activity
.identical protein binding
.ligase activity
  + 3 more...
.beta-catenin destruction complex
.plasma membrane
.cytosol
  + 3 more...
9 EBI-357355,EBI-356928 RPAP3  
  .N/A .N/A .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites75
blood24
bone13
bone marrow82
brain18
cervix41
embryonic tissue61
eye23
heart22
intestine47
kidney18
liver53
lung35
lymph45
lymph node33
mammary gland52
mouth30
muscle28
ovary29
pancreas9
pharynx98
placenta24
prostate26
skin61
stomach20
testis22
thymus25
thyroid42
tonsil58
trachea38
uterus34
vascular38
Health State
TissuesTPM*
normal29
adrenal tumor79
breast (mammary gland) tumor85
cervical tumor57
chondrosarcoma12
colorectal tumor62
gastrointestinal tumor33
germ cell tumor26
glioma74
head and neck tumor29
kidney tumor14
leukemia42
liver tumor20
lung tumor9
lymphoma55
non-neoplasia10
ovarian tumor26
primitive neuroectodermal tumor of the CNS7
prostate cancer19
skin tumor87
soft tissue/muscle tissue tumor31
uterine tumor22
Developmental Stage
TissuesTPM*
adult27
embryoid body57
blastocyst48
fetus30
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue48.9
adrenal gland106.8
appendix75.7
bone marrow121.3
cerebral cortex30
colon86.6
duodenum66.7
esophagus62.2
gallbladder67.6
heart muscle85.6
kidney67.4
liver52
lung56.3
lymph node130.2
ovary129.8
pancreas68.3
placenta63.1
prostate60
salivary gland84.7
skin60.8
small intestine73.8
spleen80.8
stomach71.7
testis39.6
thyroid gland84.4
urinary bladder81.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300234, gene) Ubiquitously expressed transcript; UXTOMIM


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