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> Protein (NX_Q9UFD9)
Protein (NX_Q9UFD9)
Protein
Gene SymbolRIMBP3 to neXtProt (NX_Q9UFD9)
DescriptionRIMS-binding protein 3A
Chromosome22
Location22q11.21 (20456003 ~ 20461786) to Ensembl
Sequene Features : Isoforms 1, Variants 57, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 57 0
2014-09-19protein level
1 40 0
2014-05-27protein level
1 40 1
2014-02-25protein level
1 40 1
2013-12-09protein level
1 33 1
2013-11-01protein level
1 33 1
2013-09-12protein level
1 33 1
2013-08-17protein level
1 33 1
2013-07-15protein level
1 22 0
2013-06-11protein level
1 22 0
2013-02-12protein level
1 11 0
2012-12-20protein level
1 11 0
2012-10-30protein level
1 14 0
2012-10-07protein level
1 14 0
2012-08-24protein level
1 13 0
2012-07-28protein level
1 14 0
2012-06-08protein level
1 23 0
2012-05-07protein level
1 22 0
2012-04-10protein level
1 22 0
2012-01-13protein level
1 35 0
2011-12-20protein level
1 35 0
2011-11-11protein level
1 35 0
2011-08-23protein level
1 35 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UFD9-1
8 0 62 180604.1545
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10182375,EBI-1055079 POLR1C  
  .negative regulation of gene expression, epigenetic
.innate immune response
.regulation of gene expression, epigenetic
  + 9 more...
.DNA-directed RNA polymerase activity
.DNA binding
.cytosol
.DNA-directed RNA polymerase I complex
.DNA-directed RNA polymerase III complex
.nucleoplasm
2 EBI-10182375,EBI-744798 TRAF3IP2  
  .immunoglobulin secretion
.positive regulation of I-kappaB kinase/NF-kappaB signaling
.intracellular signal transduction
  + 3 more...
.N/A .N/A
3 EBI-10182375,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
4 EBI-10182375,EBI-745213 AQP1  
  .cation transmembrane transport
.maintenance of symbiont-containing vacuole by host
.ammonium transmembrane transport
  + 60 more...
.carbon dioxide transmembrane transporter activity
.nitric oxide transmembrane transporter activity
.transmembrane transporter activity
  + 8 more...
.extracellular exosome
.apical part of cell
.axon terminus
  + 12 more...
5 EBI-10182375,EBI-10192698 CREB5  
  .adipose tissue development
.positive regulation of transcription, DNA-templated
.fat cell differentiation
.transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.extracellular exosome
.nucleus
6 EBI-10182375,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
7 EBI-10182375,EBI-1181405 PRKAA1  
  .negative regulation of glucose import in response to insulin stimulus
.regulation of energy homeostasis
.response to camptothecin
  + 42 more...
.[acetyl-CoA carboxylase] kinase activity
.tau-protein kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
  + 7 more...
.AMP-activated protein kinase complex
.apical plasma membrane
.cytosol
  + 4 more...
8 EBI-10182375,EBI-949814 NOXA1  
  .regulation of respiratory burst
.regulation of hydrogen peroxide metabolic process
.small GTPase mediated signal transduction
.superoxide metabolic process
.Rac GTPase binding
.enzyme binding
.SH3 domain binding
.superoxide-generating NADPH oxidase activator activity
.NADPH oxidase complex
.cytosol
9 EBI-10182375,EBI-744545 CATSPER1  
  .membrane depolarization during action potential
.calcium ion import
.regulation of cilium beat frequency involved in ciliary motility
  + 9 more...
.voltage-gated calcium channel activity
.calcium activated cation channel activity
.CatSper complex
.motile cilium
.plasma membrane
10 EBI-10182375,EBI-948288 ZNF488  
  .positive regulation of oligodendrocyte differentiation
.negative regulation of transcription, DNA-templated
.oligodendrocyte development
  + 2 more...
.metal ion binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
11 EBI-10182375,EBI-742953 DGCR6L  
  .N/A .N/A .nucleus
12 EBI-10182375,EBI-2339898 FANCL  
  .regulation of cell proliferation
.gamete generation
.cellular response to DNA damage stimulus
  + 3 more...
.ubiquitin protein ligase activity
.ubiquitin protein ligase binding
.ligase activity
  + 2 more...
.Fanconi anaemia nuclear complex
.cytoplasm
.nucleoplasm
.nuclear envelope
13 EBI-10182375,EBI-2557649 PPIL1  
  .protein folding
.protein peptidyl-prolyl isomerization
.mRNA splicing, via spliceosome
.peptidyl-prolyl cis-trans isomerase activity .catalytic step 2 spliceosome
.extracellular exosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
eye4
lung8
testis66
uterus4
Health State
TissuesTPM*
normal5
leukemia10
lung tumor9
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult2
fetus7
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis23.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612699, gene) Rims-binding protein 3; RIMBP3OMIM


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