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> Protein (NX_Q9UGI0)
Protein (NX_Q9UGI0)
Protein
Gene SymbolZRANB1 to neXtProt (NX_Q9UGI0)
DescriptionUbiquitin thioesterase ZRANB1
Chromosome10
Location10q26.13 (126630692 ~ 126676758) to Ensembl
Sequene Features : Isoforms 1, Variants 58, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein K33-linked deubiquitination
.protein deubiquitination involved in ubiquitin-dependent protein catabolic process
.protein K63-linked deubiquitination
  + 6 more...
.K63-linked polyubiquitin binding
.zinc ion binding
.ubiquitin-specific protease activity
.cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 58 3
2014-09-19protein level
1 44 3
2014-05-27protein level
1 44 3
2014-02-25protein level
1 44 3
2013-12-09protein level
1 39 3
2013-11-01protein level
1 37 3
2013-09-12protein level
1 37 3
2013-08-17protein level
1 37 3
2013-07-15protein level
1 23 2
2013-06-11protein level
1 23 2
2013-02-12protein level
1 9 1
2012-12-20protein level
1 9 1
2012-10-30protein level
1 11 1
2012-10-07protein level
1 11 1
2012-08-24protein level
1 9 1
2012-07-28protein level
1 9 1
2012-06-08protein level
1 19 1
2012-05-07protein level
1 17 1
2012-04-10protein level
1 17 1
2012-01-13protein level
1 13 1
2011-12-20protein level
1 13 1
2011-11-11protein level
1 13 1
2011-08-23protein level
1 13 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UGI0-1
37 0 0 80915.5004
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-527853,EBI-3390054 UBC  
  .programmed necrotic cell death
.apoptotic signaling pathway
.energy homeostasis
  + 90 more...
.poly(A) RNA binding
.protease binding
.extracellular exosome
.endocytic vesicle membrane
.endosome membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bone27
brain25
connective tissue53
embryonic tissue37
eye86
heart44
intestine51
kidney56
liver43
lung47
lymph node11
mammary gland33
mouth30
muscle28
nerve193
ovary68
pancreas14
pharynx24
placenta31
prostate42
skin52
spleen18
stomach10
testis29
thymus37
thyroid85
trachea77
uterus43
vascular19
Health State
TissuesTPM*
normal50
breast (mammary gland) tumor42
chondrosarcoma48
colorectal tumor62
gastrointestinal tumor25
germ cell tumor26
head and neck tumor37
kidney tumor14
liver tumor20
lung tumor19
non-neoplasia31
ovarian tumor65
pancreatic tumor9
primitive neuroectodermal tumor of the CNS39
prostate cancer38
retinoblastoma64
skin tumor15
soft tissue/muscle tissue tumor79
uterine tumor66
Developmental Stage
TissuesTPM*
adult42
embryoid body42
blastocyst16
neonate32
fetus104
infant85
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.9
adrenal gland25
appendix8.7
bone marrow14.6
cerebral cortex16
colon8.9
duodenum7.1
esophagus12.6
gallbladder13.3
heart muscle15.9
kidney10.3
liver11.4
lung11.8
lymph node9.6
ovary21.3
pancreas5.5
placenta11.5
prostate12
salivary gland8.7
skin12.5
small intestine8
spleen9.6
stomach8.4
testis19.7
thyroid gland13.7
urinary bladder12.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611749, gene) Zinc finger- and ran-binding domain-containing protein 1; ZRANB1OMIM


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