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> Protein (NX_Q9UHA4)
Protein (NX_Q9UHA4)
Protein
Gene SymbolLAMTOR3 to neXtProt (NX_Q9UHA4)
DescriptionRagulator complex protein LAMTOR3
Chromosome4
Location4q23 (100799493 ~ 100815647) to Ensembl
Sequene Features : Isoforms 2, Variants 7, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to amino acid stimulus
.positive regulation of GTPase activity
.cellular protein localization
.positive regulation of TOR signaling
.N/A .Ragulator complex
.extracellular exosome
.focal adhesion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 7 1
2014-09-19protein level
2 6 1
2014-05-27protein level
2 6 1
2014-02-25protein level
2 6 1
2013-12-09protein level
2 2 1
2013-11-01protein level
2 2 0
2013-09-12protein level
2 2 0
2013-08-17protein level
2 2 0
2013-07-15protein level
2 2 0
2013-06-11protein level
2 2 0
2013-02-12protein level
1 0 0
2012-12-20protein level
1 0 0
2012-10-30protein level
1 0 0
2012-10-07protein level
1 0 0
2012-08-24protein level
1 0 0
2012-07-28protein level
1 0 0
2012-06-08protein level
1 1 0
2012-05-07protein level
1 4 0
2012-04-10protein level
1 4 0
2012-01-13protein level
1 2 0
2011-12-20protein level
1 2 0
2011-11-11protein level
1 2 0
2011-08-23protein level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UHA4-1
1 4 0 13614.2183
NX_Q9UHA4-2
1 4 0 12932.912
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1038192,EBI-9978316 SLC38A9  
  .cellular response to amino acid stimulus
.positive regulation of TOR signaling
.amino acid transmembrane transport
.amino acid transmembrane transporter activity .late endosome membrane
.integral component of membrane
.late endosome
  + 2 more...
2 EBI-1038192,EBI-740897 NIF3L1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription, DNA-templated
.neuron differentiation
.identical protein binding
.transcription factor binding
.mitochondrion
.cytoplasm
.nucleus
3 EBI-1038192,EBI-2643704 LAMTOR2  
  .cellular response to amino acid stimulus
.positive regulation of GTPase activity
.cellular protein localization
  + 3 more...
.N/A .Ragulator complex
.extracellular exosome
.late endosome
.lysosomal membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland151
bladder368
blood73
bone69
bone marrow266
brain80
connective tissue26
ear62
embryonic tissue46
eye62
heart78
intestine30
kidney90
larynx42
liver19
lung65
lymph node55
mammary gland119
mouth60
muscle18
nerve193
ovary29
pancreas168
parathyroid388
pharynx49
pituitary gland181
placenta91
prostate84
salivary gland345
skin56
spleen18
stomach114
testis66
thymus25
trachea193
uterus103
vascular116
Health State
TissuesTPM*
normal84
adrenal tumor316
bladder carcinoma625
breast (mammary gland) tumor64
chondrosarcoma84
colorectal tumor35
gastrointestinal tumor33
germ cell tumor68
glioma65
head and neck tumor37
kidney tumor101
leukemia158
lung tumor48
non-neoplasia10
ovarian tumor26
pancreatic tumor28
primitive neuroectodermal tumor of the CNS31
prostate cancer115
retinoblastoma43
skin tumor71
soft tissue/muscle tissue tumor87
Developmental Stage
TissuesTPM*
adult83
embryoid body28
blastocyst32
fetus66
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue24.1
adrenal gland47.3
appendix33
bone marrow41
cerebral cortex33.1
colon45
duodenum36.7
esophagus51
gallbladder40.7
heart muscle35.3
kidney50.2
liver17.4
lung30.4
lymph node36.5
ovary46.3
pancreas16
placenta39.8
prostate43
salivary gland32.6
skin33.4
small intestine37.2
spleen25
stomach36.4
testis30.6
thyroid gland60
urinary bladder46.6
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowLow
breastLow
bronchusMedium
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleHigh
lungHigh
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandHigh
placentaMedium
prostateHigh
rectumMedium
salivary glandMedium
seminal vesicleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Low
spleenLow
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandHigh
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603296, gene) Late endosomal/lysosomal adaptor, mitogen-activated protein kinaseOMIM


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