Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9UHB4)
Protein (NX_Q9UHB4)
Protein
Gene SymbolNDOR1 to neXtProt (NX_Q9UHB4)
DescriptionNADPH-dependent diflavin oxidoreductase 1
Chromosome9
Location9q34.3 (140100147 ~ 140111461) to Ensembl
Sequene Features : Isoforms 4, Variants 78, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.oxidation-reduction process
.small molecule metabolic process
.cellular response to menadione
  + 2 more...
.NADP binding
.flavin adenine dinucleotide binding
.oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
  + 4 more...
.perinuclear region of cytoplasm
.intermediate filament cytoskeleton
.cytosol
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 78 1
2014-09-19protein level
4 68 1
2014-05-27protein level
4 68 1
2014-02-25protein level
3 68 1
2013-12-09protein level
3 54 1
2013-11-01protein level
3 52 1
2013-09-12protein level
3 52 1
2013-08-17protein level
3 52 1
2013-07-15protein level
3 37 0
2013-06-11protein level
3 37 0
2013-02-12protein level
2 25 0
2012-12-20protein level
2 23 0
2012-10-30protein level
2 23 0
2012-10-07protein level
2 23 0
2012-08-24protein level
2 23 0
2012-07-28protein level
2 23 0
2012-06-08protein level
2 23 0
2012-05-07protein level
2 22 0
2012-04-10protein level
2 22 0
2012-01-13protein level
2 11 0
2011-12-20protein level
2 11 0
2011-11-11protein level
2 11 0
2011-08-23protein level
2 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UHB4-1
0 26 0 66720.0395
NX_Q9UHB4-2
1 26 0 67644.5438
NX_Q9UHB4-3
2 22 0 58417.9655
NX_Q9UHB4-4
1 24 0 65900.6069
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10249760,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
2 EBI-10249760,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
3 EBI-10249760,EBI-2349927 EFHC2  
  .N/A .calcium ion binding .N/A
4 EBI-10249760,EBI-750511 CIAPIN1  
  .small molecule metabolic process
.negative regulation of apoptotic process
.hemopoiesis
  + 2 more...
.2 iron, 2 sulfur cluster binding
.metal ion binding
.electron carrier activity
.mitochondrial intermembrane space
.cytoplasm
.nucleolus
.nucleoplasm
5 EBI-10249760,EBI-740781 TCHP  
  .negative regulation of cell growth
.apoptotic process
.N/A .apical cortex
.keratin filament
.plasma membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland151
ascites25
bladder100
blood16
bone41
bone marrow20
brain31
cervix20
embryonic tissue56
esophagus49
eye38
intestine21
kidney4
liver14
lung14
lymph node55
mammary gland26
ovary19
pancreas9
placenta10
prostate21
salivary gland49
skin56
spleen74
stomach94
testis20
thymus87
thyroid85
trachea57
uterus30
Health State
TissuesTPM*
normal26
breast (mammary gland) tumor42
chondrosarcoma24
colorectal tumor26
esophageal tumor57
gastrointestinal tumor67
germ cell tumor18
glioma18
head and neck tumor22
leukemia31
liver tumor20
lung tumor29
lymphoma83
non-neoplasia31
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS15
retinoblastoma86
skin tumor87
soft tissue/muscle tissue tumor7
uterine tumor44
Developmental Stage
TissuesTPM*
adult22
embryoid body42
blastocyst81
fetus16
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.1
adrenal gland3.3
appendix6.8
bone marrow7.1
cerebral cortex3.3
colon3.4
duodenum6
esophagus2.3
gallbladder3.5
heart muscle1.8
kidney3.9
lung4.4
lymph node7.5
ovary1.9
pancreas3
placenta3
prostate3.8
salivary gland5
skin5.6
small intestine5.3
spleen7.7
stomach5.2
testis7.9
thyroid gland3.3
urinary bladder3.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606073, gene) Nadph-dependent diflavin oxidoreductase 1; NDOR1OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2020 (C) Yonsei Proteome Research Center